ID   RLF10_ARATH             Reviewed;          73 AA.
AC   O65919;
DT   28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Protein RALF-like 10;
DE   Flags: Precursor;
GN   Name=RALFL10; OrderedLocusNames=At2g19020; ORFNames=F19F24, T20K24.3;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=12611624;
RA   Olsen A.N., Mundy J., Skriver K.;
RT   "Peptomics, identification of novel cationic Arabidopsis peptides with
RT   conserved sequence motifs.";
RL   In Silico Biol. 2:441-451(2002).
CC   -!- FUNCTION: Cell signaling peptide that may regulate plant stress,
CC       growth, and development. Mediates a rapid alkalinization of
CC       extracellular space by mediating a transient increase in the
CC       cytoplasmic Ca(2+) concentration leading to a calcium-dependent
CC       signaling events through a cell surface receptor and a concomitant
CC       activation of some intracellular mitogen-activated protein kinases (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in flowers.
CC       {ECO:0000269|PubMed:12611624}.
CC   -!- SIMILARITY: Belongs to the plant rapid alkalinization factor (RALF)
CC       family. {ECO:0000305}.
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DR   EMBL; AC002392; AAD12020.1; -; Genomic_DNA.
DR   EMBL; AC003673; AAM14886.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06839.1; -; Genomic_DNA.
DR   PIR; T01630; T01630.
DR   RefSeq; NP_179492.1; NM_127459.2.
DR   AlphaFoldDB; O65919; -.
DR   SMR; O65919; -.
DR   STRING; 3702.AT2G19020.1; -.
DR   PaxDb; O65919; -.
DR   PRIDE; O65919; -.
DR   EnsemblPlants; AT2G19020.1; AT2G19020.1; AT2G19020.
DR   GeneID; 816419; -.
DR   Gramene; AT2G19020.1; AT2G19020.1; AT2G19020.
DR   KEGG; ath:AT2G19020; -.
DR   Araport; AT2G19020; -.
DR   TAIR; locus:2044435; AT2G19020.
DR   eggNOG; ENOG502SYWJ; Eukaryota.
DR   HOGENOM; CLU_200725_0_0_1; -.
DR   InParanoid; O65919; -.
DR   OrthoDB; 1644686at2759; -.
DR   PhylomeDB; O65919; -.
DR   PRO; PR:O65919; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; O65919; baseline.
DR   GO; GO:0048046; C:apoplast; ISS:TAIR.
DR   GO; GO:0005179; F:hormone activity; ISS:UniProtKB.
DR   GO; GO:0019722; P:calcium-mediated signaling; ISS:UniProtKB.
DR   GO; GO:0007267; P:cell-cell signaling; ISS:TAIR.
DR   InterPro; IPR008801; RALF.
DR   Pfam; PF05498; RALF; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Hormone; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..73
FT                   /note="Protein RALF-like 10"
FT                   /id="PRO_0000420301"
FT   DISULFID        35..44
FT                   /evidence="ECO:0000250"
FT   DISULFID        64..70
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   73 AA;  7979 MW;  9E106570B649C904 CRC64;
     MKALVICLLV IFAAVIAVPV ESRRKHLDYG VITKCAGPNP PPGCYPPGAQ QKNPTPANEY
     RRGCSKITRC KRD