RLF13_ARATH
ID RLF13_ARATH Reviewed; 72 AA.
AC F4ISE2;
DT 28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 48.
DE RecName: Full=Protein RALF-like 13;
DE Flags: Precursor;
GN Name=RALFL13; OrderedLocusNames=At2g19045; ORFNames=T20K24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12611624;
RA Olsen A.N., Mundy J., Skriver K.;
RT "Peptomics, identification of novel cationic Arabidopsis peptides with
RT conserved sequence motifs.";
RL In Silico Biol. 2:441-451(2002).
CC -!- FUNCTION: Cell signaling peptide that may regulate plant stress,
CC growth, and development. Mediates a rapid alkalinization of
CC extracellular space by mediating a transient increase in the
CC cytoplasmic Ca(2+) concentration leading to a calcium-dependent
CC signaling events through a cell surface receptor and a concomitant
CC activation of some intracellular mitogen-activated protein kinases (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the plant rapid alkalinization factor (RALF)
CC family. {ECO:0000305}.
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DR EMBL; AC002392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC06842.1; -; Genomic_DNA.
DR RefSeq; NP_001077916.1; NM_001084447.2.
DR AlphaFoldDB; F4ISE2; -.
DR STRING; 3702.AT2G19045.1; -.
DR PaxDb; F4ISE2; -.
DR PRIDE; F4ISE2; -.
DR ProteomicsDB; 228089; -.
DR EnsemblPlants; AT2G19045.1; AT2G19045.1; AT2G19045.
DR GeneID; 5007885; -.
DR Gramene; AT2G19045.1; AT2G19045.1; AT2G19045.
DR KEGG; ath:AT2G19045; -.
DR Araport; AT2G19045; -.
DR TAIR; locus:4010713632; AT2G19045.
DR eggNOG; ENOG502SYWJ; Eukaryota.
DR HOGENOM; CLU_200725_0_0_1; -.
DR InParanoid; F4ISE2; -.
DR OrthoDB; 1644686at2759; -.
DR PRO; PR:F4ISE2; -.
DR Proteomes; UP000006548; Chromosome 2.
DR Genevisible; F4ISE2; AT.
DR GO; GO:0048046; C:apoplast; ISS:TAIR.
DR GO; GO:0005179; F:hormone activity; ISS:UniProtKB.
DR GO; GO:0019722; P:calcium-mediated signaling; ISS:UniProtKB.
DR GO; GO:0007267; P:cell-cell signaling; ISS:TAIR.
DR InterPro; IPR008801; RALF.
DR Pfam; PF05498; RALF; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Hormone; Reference proteome; Secreted; Signal.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..72
FT /note="Protein RALF-like 13"
FT /id="PRO_0000420304"
FT DISULFID 34..43
FT /evidence="ECO:0000250"
FT DISULFID 63..69
FT /evidence="ECO:0000250"
SQ SEQUENCE 72 AA; 7881 MW; 951609FCA2F41D05 CRC64;
MKAWVICLLV ICAAVIAEPV ESRNYIEYGA INKCAGPNPP PGCNPPGAEQ KNPNPVNEYS
RGCSKIHRCR RD