RLF14_ARATH
ID RLF14_ARATH Reviewed; 101 AA.
AC Q9SIU6;
DT 28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Protein RALF-like 14;
DE Flags: Precursor;
GN Name=RALFL14; OrderedLocusNames=At2g20660; ORFNames=F23N11.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12611624;
RA Olsen A.N., Mundy J., Skriver K.;
RT "Peptomics, identification of novel cationic Arabidopsis peptides with
RT conserved sequence motifs.";
RL In Silico Biol. 2:441-451(2002).
CC -!- FUNCTION: Cell signaling peptide that may regulate plant stress,
CC growth, and development. Mediates a rapid alkalinization of
CC extracellular space by mediating a transient increase in the
CC cytoplasmic Ca(2+) concentration leading to a calcium-dependent
CC signaling events through a cell surface receptor and a concomitant
CC activation of some intracellular mitogen-activated protein kinases (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- PTM: Proteolytically cleaved, probably by S1P, a subtilisin-like serine
CC protease (subtilase). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the plant rapid alkalinization factor (RALF)
CC family. {ECO:0000305}.
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DR EMBL; AC007048; AAD21703.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07054.1; -; Genomic_DNA.
DR EMBL; DQ056538; AAY78690.1; -; mRNA.
DR PIR; G84591; G84591.
DR RefSeq; NP_179658.1; NM_127630.1.
DR AlphaFoldDB; Q9SIU6; -.
DR STRING; 3702.AT2G20660.1; -.
DR PaxDb; Q9SIU6; -.
DR PRIDE; Q9SIU6; -.
DR EnsemblPlants; AT2G20660.1; AT2G20660.1; AT2G20660.
DR GeneID; 816594; -.
DR Gramene; AT2G20660.1; AT2G20660.1; AT2G20660.
DR KEGG; ath:AT2G20660; -.
DR Araport; AT2G20660; -.
DR TAIR; locus:2046031; AT2G20660.
DR HOGENOM; CLU_2295534_0_0_1; -.
DR InParanoid; Q9SIU6; -.
DR OMA; QGTRYIN; -.
DR OrthoDB; 1512493at2759; -.
DR PhylomeDB; Q9SIU6; -.
DR PRO; PR:Q9SIU6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIU6; baseline and differential.
DR Genevisible; Q9SIU6; AT.
DR GO; GO:0048046; C:apoplast; ISS:TAIR.
DR GO; GO:0005179; F:hormone activity; ISS:UniProtKB.
DR GO; GO:0019722; P:calcium-mediated signaling; ISS:UniProtKB.
DR GO; GO:0007267; P:cell-cell signaling; ISS:TAIR.
DR InterPro; IPR008801; RALF.
DR Pfam; PF05498; RALF; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Hormone; Reference proteome; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT PROPEP 22..56
FT /note="Removed in mature form"
FT /evidence="ECO:0000250"
FT /id="PRO_0000420305"
FT CHAIN 57..101
FT /note="Protein RALF-like 14"
FT /evidence="ECO:0000250"
FT /id="PRO_0000420306"
FT SITE 53..54
FT /note="Required for proteolytic cleavage"
FT /evidence="ECO:0000250"
FT DISULFID 90..96
FT /evidence="ECO:0000250"
SQ SEQUENCE 101 AA; 11719 MW; 6459A1D04AF914D6 CRC64;
MKLLIFAVII SVVLFPVLVS SRTIKCDQLS GKCINGEEKE IMNMRLGLDV SSRRILQASR
YISYEALKKN LPDNRRGEPD QRDNPYRRSC DVHSHCYRFT N