ID   RLGP1_ORYSJ             Reviewed;         226 AA.
AC   P25766; Q6ENK7;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   27-JUN-2006, sequence version 2.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=Ras-related protein RGP1;
DE   AltName: Full=GTP-binding regulatory protein RGP1;
GN   Name=RGP1; OrderedLocusNames=Os09g0281700, LOC_Os09g10940;
GN   ORFNames=P0645D04.22-1;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Gimbozu;
RX   PubMed=1715972; DOI=10.1007/bf00282470;
RA   Sano H., Youssefian S.;
RT   "A novel ras-related rgp1 gene encoding a GTP-binding protein has reduced
RT   expression in 5-azacytidine-induced dwarf rice.";
RL   Mol. Gen. Genet. 228:227-232(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
CC   -!- FUNCTION: May play an important role in plant growth and development.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: During seedling RGP1 expression was first observed
CC       14 days after germination, reaching a maximum level between 28 and 42
CC       days, and gradually decreased thereafter until 63 days when it attained
CC       the same level of expression as in 14-day old seedlings.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC       {ECO:0000305}.
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DR   EMBL; X59276; CAA41966.1; -; mRNA.
DR   EMBL; AP006727; BAD29646.1; -; Genomic_DNA.
DR   EMBL; AP014965; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; S16554; S16554.
DR   RefSeq; XP_015612602.1; XM_015757116.1.
DR   AlphaFoldDB; P25766; -.
DR   SMR; P25766; -.
DR   STRING; 4530.OS09T0281700-01; -.
DR   PaxDb; P25766; -.
DR   PRIDE; P25766; -.
DR   GeneID; 4346614; -.
DR   KEGG; osa:4346614; -.
DR   InParanoid; P25766; -.
DR   OrthoDB; 1133775at2759; -.
DR   Proteomes; UP000000763; Chromosome 9.
DR   Proteomes; UP000059680; Chromosome 9.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR   GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF00071; Ras; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51419; RAB; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding;
KW   Prenylation; Reference proteome.
FT   CHAIN           1..226
FT                   /note="Ras-related protein RGP1"
FT                   /id="PRO_0000121296"
FT   MOTIF           47..55
FT                   /note="Effector region"
FT                   /evidence="ECO:0000255"
FT   BINDING         25..32
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         73..77
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         131..134
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   LIPID           223
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
FT   LIPID           224
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        37
FT                   /note="R -> G (in Ref. 1; CAA41966)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        71..72
FT                   /note="IW -> TR (in Ref. 1; CAA41966)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        168
FT                   /note="V -> L (in Ref. 1; CAA41966)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   226 AA;  24979 MW;  87B70EC90EFFBD69 CRC64;
     MSRGGGSYGE VGQKIDYVFK VVLIGDSAVG KSQLLARFAR NEFNLDSKAT IGVEFQTRTL
     HIDARTVKAQ IWDTAGQERY RAVTSAYYRG AVGAMLVYDI TKRQSFDHVA RWLEELRGHA
     DKNIVIMLIG NKSDLGTLRV VPTEDAKEFA ERENLFFMET SALESTNVEN AFMTVLTEIY
     RIVSKKNLVA NEEVDSSGNS SLLKGTKIVV PGQEPAPPTK ASCCMS