RLGP2_ORYSJ
ID RLGP2_ORYSJ Reviewed; 217 AA.
AC Q40723; Q75IH2;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 2.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Ras-related protein RGP2;
DE AltName: Full=GTP-binding regulatory protein RGP2;
GN Name=RGP2; OrderedLocusNames=Os05g0280200, LOC_Os05g20050;
GN ORFNames=P0048F12.8;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Gimbozu;
RX PubMed=8455556; DOI=10.1007/bf00282800;
RA Youssefian S., Nakamura M., Sano H.;
RT "Molecular characterization of rgp2, a gene encoding a small GTP-binding
RT protein from rice.";
RL Mol. Gen. Genet. 237:187-192(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000305}.
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DR EMBL; D13152; BAA02437.1; -; mRNA.
DR EMBL; AC130609; AAS98506.1; -; Genomic_DNA.
DR EMBL; AP014961; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; S30273; S30273.
DR RefSeq; XP_015637295.1; XM_015781809.1.
DR AlphaFoldDB; Q40723; -.
DR SMR; Q40723; -.
DR STRING; 4530.OS05T0280200-01; -.
DR PaxDb; Q40723; -.
DR PRIDE; Q40723; -.
DR GeneID; 4338288; -.
DR KEGG; osa:4338288; -.
DR InParanoid; Q40723; -.
DR OrthoDB; 1133775at2759; -.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR Pfam; PF00071; Ras; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00231; small_GTP; 1.
DR PROSITE; PS51419; RAB; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding;
KW Prenylation; Reference proteome.
FT CHAIN 1..217
FT /note="Ras-related protein RGP2"
FT /id="PRO_0000121173"
FT BINDING 19..26
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 67..71
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT BINDING 125..128
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000250"
FT LIPID 214
FT /note="S-geranylgeranyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 215
FT /note="S-geranylgeranyl cysteine"
FT /evidence="ECO:0000250"
FT CONFLICT 21
FT /note="S -> T (in Ref. 1; BAA02437)"
FT /evidence="ECO:0000305"
FT CONFLICT 192
FT /note="A -> R (in Ref. 1; BAA02437)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 217 AA; 23790 MW; C0729E458B48D9F0 CRC64;
MGGRVDHEYS YLFKMVLIGD SGVGKSNILS RFTRNHFSLD SKSTIGVEFA TKSLQMEGKT
IKAQIWDTAG QERYRAITSA YYRGAVGALL VYDITKRQSF DNVHRWLREL RDHADSSIVI
MMVGNKSDLI HLRAVSEDEG KALAEKEGLF FLETSAMEAV NVEEAFQTII TEVYGIVNRK
ALAAKEAAAA SAPLPSQGKT ISIDSAAGNT KRACCSA