RLK10_ORYSJ
ID RLK10_ORYSJ Reviewed; 605 AA.
AC D7UPN3; A0A0P0XNY3; A0A0P0XPR6; A3C0J5; B7E6S3; C7J6F9;
DT 09-JAN-2013, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=LysM domain receptor-like kinase 10 {ECO:0000303|PubMed:21070404};
DE Short=OsLysM-RLK10 {ECO:0000303|PubMed:21070404};
DE EC=2.7.11.1 {ECO:0000305};
DE AltName: Full=LysM-containing receptor-like kinase 10 {ECO:0000305};
DE AltName: Full=Receptor-like cytoplasmic kinase 276 {ECO:0000303|PubMed:19825577};
DE Short=OsRLCK276 {ECO:0000303|PubMed:19825577};
DE Flags: Precursor;
GN Name=RLK10 {ECO:0000303|PubMed:21070404};
GN Synonyms=RLCK276 {ECO:0000303|PubMed:19825577};
GN OrderedLocusNames=Os09g0511000 {ECO:0000312|EMBL:BAT08907.1},
GN LOC_Os09g33630 {ECO:0000305};
GN ORFNames=OsJ_29979 {ECO:0000312|EMBL:EAZ45334.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RC STRAIN=cv. Nipponbare;
RX PubMed=21070404; DOI=10.1111/j.1365-313x.2010.04324.x;
RA Shimizu T., Nakano T., Takamizawa D., Desaki Y., Ishii-Minami N.,
RA Nishizawa Y., Minami E., Okada K., Yamane H., Kaku H., Shibuya N.;
RT "Two LysM receptor molecules, CEBiP and OsCERK1, cooperatively regulate
RT chitin elicitor signaling in rice.";
RL Plant J. 64:204-214(2010).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19825577; DOI=10.1093/mp/ssn047;
RA Vij S., Giri J., Dansana P.K., Kapoor S., Tyagi A.K.;
RT "The receptor-like cytoplasmic kinase (OsRLCK) gene family in rice:
RT organization, phylogenetic relationship, and expression during development
RT and stress.";
RL Mol. Plant 1:732-750(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1;
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass membrane
CC protein {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=D7UPN3-1; Sequence=Displayed;
CC Name=2;
CC IsoId=D7UPN3-2; Sequence=VSP_044681;
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAH94662.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAT08907.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAT08908.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EAZ45334.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB510402; BAJ09794.1; -; mRNA.
DR EMBL; AP008215; BAH94662.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014965; BAT08907.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014965; BAT08908.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CM000146; EAZ45334.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK061724; BAG88070.1; -; mRNA.
DR RefSeq; XP_015611968.1; XM_015756482.1. [D7UPN3-1]
DR AlphaFoldDB; D7UPN3; -.
DR SMR; D7UPN3; -.
DR STRING; 4530.OS09T0511000-02; -.
DR PaxDb; D7UPN3; -.
DR PRIDE; D7UPN3; -.
DR GeneID; 9270778; -.
DR KEGG; osa:9270778; -.
DR eggNOG; ENOG502QPX8; Eukaryota.
DR HOGENOM; CLU_000288_21_4_1; -.
DR InParanoid; D7UPN3; -.
DR OrthoDB; 684563at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000007752; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR Genevisible; D7UPN3; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008061; F:chitin binding; IDA:UniProtKB.
DR GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0019199; F:transmembrane receptor protein kinase activity; IEA:InterPro.
DR GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR GO; GO:0010200; P:response to chitin; IDA:UniProtKB.
DR InterPro; IPR044812; CERK1/LYK3-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR46204; PTHR46204; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; ATP-binding; Cell membrane; Chitin-binding;
KW Disulfide bond; Glycoprotein; Kinase; Membrane; Nucleotide-binding;
KW Phosphoprotein; Plant defense; Receptor; Reference proteome;
KW Serine/threonine-protein kinase; Signal; Transferase; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..605
FT /note="LysM domain receptor-like kinase 10"
FT /id="PRO_0000420827"
FT TOPO_DOM 21..245
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 246..266
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 267..605
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 174..221
FT /note="LysM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01118"
FT DOMAIN 317..591
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT ACT_SITE 436
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING 115..121
FT /ligand="chitin"
FT /ligand_id="ChEBI:CHEBI:17029"
FT /evidence="ECO:0000250"
FT BINDING 142..148
FT /ligand="chitin"
FT /ligand_id="ChEBI:CHEBI:17029"
FT /evidence="ECO:0000250"
FT BINDING 323..331
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 344
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT MOD_RES 278
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
FT CARBOHYD 44
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 154
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 158
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 226
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 26..89
FT /evidence="ECO:0000250|UniProtKB:A8R7E6"
FT DISULFID 30..161
FT /evidence="ECO:0000250|UniProtKB:A8R7E6"
FT DISULFID 87..159
FT /evidence="ECO:0000250|UniProtKB:A8R7E6"
FT VAR_SEQ 1..318
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_044681"
SQ SEQUENCE 605 AA; 65205 MW; 951BE9DE32C91E6E CRC64;
MFSLPALLIG ACAFAAAAVA ASGDGCRAGC SLAIAAYYFS EGSNLTFIAT IFAIGGGGYQ
ALLPYNPAIT NPDYVVTGDR VLVPFPCSCL GLPAAPASTF LAGAIPYPLP LPRGGGDTYD
AVAANYADLT TAAWLEATNA YPPGRIPGGD GRVNVTINCS CGDERVSPRY GLFLTYPLWD
GETLESVAAQ YGFSSPAEME LIRRYNPGMG GVSGKGIVFI PVKDPNGSYH PLKSGGMGNS
LSGGAIAGIV IACIAIFIVA IWLIIMFYRW QKFRKATSRP SPEETSHLDD ASQAEGIKVE
RSIEFSYEEI FNATQGFSME HKIGQGGFGS VYYAELRGEK TAIKKMGMQA TQEFLAELKV
LTHVHHLNLV RLIGYCVENC LFLVYEFIDN GNLSQHLQRT GYAPLSWATR VQIALDSARG
LEYLHEHVVP VYVHRDIKSA NILLDKDFRA KIADFGLAKL TEVGSMSQSL STRVAGTFGY
MPPEARYGEV SPKVDVYAFG VVLYELLSAK QAIVRSSESV SESKGLVFLF EEALSAPNPT
EALDELIDPS LQGDYPVDSA LKIASLAKSC THEEPGMRPT MRSVVVALMA LTANTDLRDM
DYHPF
