AB12I_ARATH
ID AB12I_ARATH Reviewed; 391 AA.
AC Q944H2; Q3EB30; Q9LVE8;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Protein ABCI12, chloroplastic;
DE AltName: Full=ABC transporter I family member 12;
DE Short=ABC transporter ABCI.12;
DE Short=AtABCI12;
DE Flags: Precursor;
GN Name=ABCI12; OrderedLocusNames=At3g21580; ORFNames=MIL23.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 187-391.
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RX PubMed=18431481; DOI=10.1371/journal.pone.0001994;
RA Zybailov B., Rutschow H., Friso G., Rudella A., Emanuelsson O., Sun Q.,
RA van Wijk K.J.;
RT "Sorting signals, N-terminal modifications and abundance of the chloroplast
RT proteome.";
RL PLoS ONE 3:E1994-E1994(2008).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:18431481}. Membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- CAUTION: Was originally thought to belong to the ABC transporter family
CC (PubMed:18299247). Lacks the conserved ABC domain, which is one of the
CC features of the ABC transporter family. {ECO:0000305|PubMed:18299247}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB02353.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAB02353.1; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB019232; BAB02353.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76525.1; -; Genomic_DNA.
DR EMBL; AK118139; BAC42764.1; -; mRNA.
DR EMBL; AF428451; AAL16220.1; -; mRNA.
DR EMBL; BT029502; ABL66758.1; -; mRNA.
DR RefSeq; NP_566688.4; NM_113053.7.
DR AlphaFoldDB; Q944H2; -.
DR SMR; Q944H2; -.
DR BioGRID; 7044; 63.
DR IntAct; Q944H2; 64.
DR STRING; 3702.AT3G21580.1; -.
DR TCDB; 3.A.1.26.12; the atp-binding cassette (abc) superfamily.
DR PaxDb; Q944H2; -.
DR PRIDE; Q944H2; -.
DR ProteomicsDB; 245129; -.
DR EnsemblPlants; AT3G21580.1; AT3G21580.1; AT3G21580.
DR GeneID; 821712; -.
DR Gramene; AT3G21580.1; AT3G21580.1; AT3G21580.
DR KEGG; ath:AT3G21580; -.
DR Araport; AT3G21580; -.
DR TAIR; locus:2089910; AT3G21580.
DR eggNOG; ENOG502QTQ5; Eukaryota.
DR HOGENOM; CLU_056469_0_1_1; -.
DR InParanoid; Q944H2; -.
DR OMA; MTRAINW; -.
DR OrthoDB; 1073007at2759; -.
DR PhylomeDB; Q944H2; -.
DR PRO; PR:Q944H2; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q944H2; baseline and differential.
DR Genevisible; Q944H2; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR InterPro; IPR003339; ABC/ECF_trnsptr_transmembrane.
DR Pfam; PF02361; CbiQ; 1.
PE 1: Evidence at protein level;
KW Chloroplast; Membrane; Plastid; Reference proteome; Transit peptide;
KW Transmembrane; Transmembrane helix.
FT TRANSIT 1..63
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 64..391
FT /note="Protein ABCI12, chloroplastic"
FT /id="PRO_0000379143"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 370..390
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 391 AA; 42938 MW; 6FD5ED106D0AD339 CRC64;
MNHSNLANPT VSLTVTLIPK HPIRHLTSPI PNRNFTNPKL LFPLRLNETP SSSLAAKRVF
IVRATVDGDG KTGNWVNRLP IPGLGAENVF RLISSATGSP IGQFISSPVT FLHSVDPRIK
LVWLLTLVVL PARANLVVRL GLVLCTALLS ILVLPRQVWI DQLARVSLLS GILFITLGLG
SDGAPPMLQS RTPPSSITSL PNLPMSLSGY SYMLLKLGPL QFTRKGLSVG STAACLTFII
FQSASICLAT TTPEQLALAL RWFLFPLTYI GVPVSEIILT LLLSLRFINL VFDEVRSVSL
GIVSRRVNWQ QLTVLETLDI FASFIRRIFK NIFRHAEQIS QAMIVRGFRG ESSSHKIYFF
SGSSNKFADF ASVLCLIGVI STALLSEYFL V
