AB13G_ARATH
ID AB13G_ARATH Reviewed; 678 AA.
AC Q9C8J8; Q8GX48;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=ABC transporter G family member 13;
DE Short=ABC transporter ABCG.13;
DE Short=AtABCG13;
DE AltName: Full=White-brown complex homolog protein 13;
DE Short=AtWBC13;
GN Name=ABCG13; Synonyms=WBC13; OrderedLocusNames=At1g51460; ORFNames=F5D21.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [5]
RP INDUCTION BY SALT.
RX PubMed=17951461; DOI=10.1104/pp.107.105676;
RA Panikashvili D., Savaldi-Goldstein S., Mandel T., Yifhar T., Franke R.B.,
RA Hoefer R., Schreiber L., Chory J., Aharoni A.;
RT "The Arabidopsis DESPERADO/AtWBC11 transporter is required for cutin and
RT wax secretion.";
RL Plant Physiol. 145:1345-1360(2007).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- INDUCTION: By NaCl. {ECO:0000269|PubMed:17951461}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC Eye pigment precursor importer (TC 3.A.1.204) subfamily. {ECO:0000305}.
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DR EMBL; AC024261; AAG52631.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32670.1; -; Genomic_DNA.
DR EMBL; AK118438; BAC43047.1; -; mRNA.
DR PIR; H96552; H96552.
DR RefSeq; NP_175557.1; NM_104024.3.
DR AlphaFoldDB; Q9C8J8; -.
DR SMR; Q9C8J8; -.
DR BioGRID; 26796; 44.
DR IntAct; Q9C8J8; 43.
DR STRING; 3702.AT1G51460.1; -.
DR TCDB; 3.A.1.204.24; the atp-binding cassette (abc) superfamily.
DR iPTMnet; Q9C8J8; -.
DR PaxDb; Q9C8J8; -.
DR PRIDE; Q9C8J8; -.
DR ProteomicsDB; 243295; -.
DR EnsemblPlants; AT1G51460.1; AT1G51460.1; AT1G51460.
DR GeneID; 841571; -.
DR Gramene; AT1G51460.1; AT1G51460.1; AT1G51460.
DR KEGG; ath:AT1G51460; -.
DR Araport; AT1G51460; -.
DR TAIR; locus:2033939; AT1G51460.
DR eggNOG; KOG0061; Eukaryota.
DR HOGENOM; CLU_000604_57_7_1; -.
DR InParanoid; Q9C8J8; -.
DR OMA; MIGVEYD; -.
DR OrthoDB; 806939at2759; -.
DR PhylomeDB; Q9C8J8; -.
DR PRO; PR:Q9C8J8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C8J8; baseline and differential.
DR Genevisible; Q9C8J8; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0080051; P:cutin transport; IMP:TAIR.
DR GO; GO:0080172; P:petal epidermis patterning; IMP:TAIR.
DR GO; GO:0009651; P:response to salt stress; IDA:UniProtKB.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Membrane; Nucleotide-binding; Phosphoprotein;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..678
FT /note="ABC transporter G family member 13"
FT /id="PRO_0000240685"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 409..429
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 446..466
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 490..510
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 513..533
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 602..622
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 10..254
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 355..567
FT /note="ABC transmembrane type-2"
FT BINDING 48..55
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT MOD_RES 658
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8RXN0"
FT CONFLICT 13
FT /note="E -> K (in Ref. 3; BAC43047)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 678 AA; 75220 MW; C36C33DF7741F63F CRC64;
MTTPEGAMYV AWEDLTVVIP NFGEGATKRL LNGVNGCGEP NRILAIMGPS GSGKSTLLDA
LAGRLAGNVV MSGKVLVNGK KRRLDFGAAA YVTQEDVLLG TLTVRESISY SAHLRLPSKL
TREEISDIVE ATITDMGLEE CSDRTIGNWH LRGISGGEKK RLSIALEVLT KPSLLFLDEP
TSGLDSASAF FVVQILRNIA SSGKTVVSSI HQPSGEVFAL FDDLLLLSGG ETVYFGEAES
ATKFFGEAGF PCPSRRNPSD HFLRCVNSDF DNVTAALVES RRINDSSFSL HQLHETTNTL
DPLDDIPTAE IRTTLVRKFK CSLYAAASRA RIQEIASIVG IVTERKKGSQ TNWWKQLRIL
TQRSFINMSR DLGYYWMRIA VYIVLSICVG SIFFNVGRNH TNVMSTAACG GFMAGFMTFM
SIGGFQSFIE EMKVFSRERL NGHYGVAVYT VSNLLSSLPF IILMCLSTSS ITIYMVRFQS
GGSHFFYNCL DLICAITTVE SCMMMIASVV PNFLMGVMLG AGYIGIMVLS AGFFRFFPDL
PMVFWRYPVS YINYGAWALQ GAYKNEMIGV EYDSPLPLVP KMKGELILQT VLGINPESSK
WLDLAVVMMI LIGYRIAFFA ILKFREKVFP VIHMLYTKRT LSHIQKRPSF RRMTPFPSRR
YPVHHALSSQ EGLNSPLH
