AB15G_ARATH
ID AB15G_ARATH Reviewed; 691 AA.
AC Q8RWI9; Q9LJC3;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 2.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=ABC transporter G family member 15;
DE Short=ABC transporter ABCG.15;
DE Short=AtABCG15;
DE AltName: Full=White-brown complex homolog protein 15;
DE Short=AtWBC15;
DE AltName: Full=White-brown complex homolog protein 22;
DE Short=AtWBC22;
GN Name=ABCG15; Synonyms=WBC15, WBC22; OrderedLocusNames=At3g21090;
GN ORFNames=MSA6.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11346655; DOI=10.1074/jbc.m103104200;
RA Sanchez-Fernandez R., Davies T.G., Coleman J.O., Rea P.A.;
RT "The Arabidopsis thaliana ABC protein superfamily, a complete inventory.";
RL J. Biol. Chem. 276:30231-30244(2001).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18299247; DOI=10.1016/j.tplants.2008.02.001;
RA Verrier P.J., Bird D., Burla B., Dassa E., Forestier C., Geisler M.,
RA Klein M., Kolukisaoglu H.U., Lee Y., Martinoia E., Murphy A., Rea P.A.,
RA Samuels L., Schulz B., Spalding E.J., Yazaki K., Theodoulou F.L.;
RT "Plant ABC proteins - a unified nomenclature and updated inventory.";
RL Trends Plant Sci. 13:151-159(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC Eye pigment precursor importer (TC 3.A.1.204) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB01452.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP000604; BAB01452.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76459.1; -; Genomic_DNA.
DR EMBL; AY093054; AAM13053.1; -; mRNA.
DR EMBL; BT000405; AAN15724.1; -; mRNA.
DR RefSeq; NP_188746.2; NM_113003.5.
DR AlphaFoldDB; Q8RWI9; -.
DR SMR; Q8RWI9; -.
DR BioGRID; 6993; 26.
DR IntAct; Q8RWI9; 26.
DR STRING; 3702.AT3G21090.1; -.
DR iPTMnet; Q8RWI9; -.
DR PaxDb; Q8RWI9; -.
DR PRIDE; Q8RWI9; -.
DR ProteomicsDB; 244560; -.
DR EnsemblPlants; AT3G21090.1; AT3G21090.1; AT3G21090.
DR GeneID; 821661; -.
DR Gramene; AT3G21090.1; AT3G21090.1; AT3G21090.
DR KEGG; ath:AT3G21090; -.
DR Araport; AT3G21090; -.
DR TAIR; locus:2092960; AT3G21090.
DR eggNOG; KOG0061; Eukaryota.
DR HOGENOM; CLU_000604_57_7_1; -.
DR InParanoid; Q8RWI9; -.
DR OMA; VIGNWHA; -.
DR OrthoDB; 806939at2759; -.
DR PhylomeDB; Q8RWI9; -.
DR PRO; PR:Q8RWI9; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8RWI9; baseline and differential.
DR Genevisible; Q8RWI9; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC_2_trans.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Membrane; Nucleotide-binding; Phosphoprotein;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..691
FT /note="ABC transporter G family member 15"
FT /id="PRO_0000240687"
FT TRANSMEM 384..404
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 414..434
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 453..473
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 491..511
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 514..534
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 548..565
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 607..627
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 25..269
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT DOMAIN 360..572
FT /note="ABC transmembrane type-2"
FT REGION 657..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..691
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 63..70
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT MOD_RES 664
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9C8K2"
FT MOD_RES 670
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8RXN0"
FT CONFLICT 149
FT /note="M -> I (in Ref. 3; AAM13053/AAN15724)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 691 AA; 77237 MW; A0D1FE00B440D61A CRC64;
MELEGSSSGR RQLPSKLEMS RGAYLAWEDL TVVIPNFSDG PTRRLLQRLN GYAEPGRIMA
IMGPSGSGKS TLLDSLAGRL ARNVVMTGNL LLNGKKARLD YGLVAYVTQE DVLLGTLTVR
ETITYSAHLR LPSDMSKEEV SDIVEGTIME LGLQDCSDRV IGNWHARGVS GGERKRVSIA
LEILTRPQIL FLDEPTSGLD SASAFFVIQA LRNIARDGRT VISSVHQPSS EVFALFDDLF
LLSSGESVYF GEAKSAVEFF AESGFPCPKK RNPSDHFLRC INSDFDTVTA TLKGSQRIQE
TPATSDPLMN LATSVIKARL VENYKRSKYA KSAKSRIREL SNIEGLEMEI RKGSEATWWK
QLRTLTARSF INMCRDVGYY WTRIISYIVV SISVGTIFYD VGYSYTSILA RVSCGGFITG
FMTFMSIGGF PSFLEEMKVF YKERLSGYYG VSVYILSNYI SSFPFLVAIS VITGTITYNL
VKFRPGFSHY AFFCLNIFFS VSVIESLMMV VASVVPNFLM GLITGAGLIG IIMMTSGFFR
LLPDLPKIFW RYPVSYISYG SWAIQGGYKN DFLGLEFEPL FPGEPKMTGE EVIEKVFGVK
VTYSKWWDLA AVVAILVCYR LLFFVVLKLR ERAGPALKAI QAKRTMRNLD RRPSFKRMPS
LSLSLSSMSS RRHQPLRSLS SQEGLNSPIH Y
