RLP1_ARATH
ID RLP1_ARATH Reviewed; 1077 AA.
AC Q9LNV9; A0A1P8AUZ2; F4HQM6; Q0WVH1; Q9LNV8;
DT 28-FEB-2018, integrated into UniProtKB/Swiss-Prot.
DT 28-FEB-2018, sequence version 2.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Receptor-like protein 1 {ECO:0000303|PubMed:18434605};
DE Short=AtRLP1 {ECO:0000303|PubMed:18434605};
DE AltName: Full=Receptor of eMax {ECO:0000303|PubMed:23898033};
DE Flags: Precursor;
GN Name=RLP1 {ECO:0000303|PubMed:18434605};
GN Synonyms=REMAX {ECO:0000303|PubMed:23898033};
GN OrderedLocusNames=At1g07390 {ECO:0000312|Araport:AT1G07390};
GN ORFNames=F22G5.27/F22G5.26 {ECO:0000312|EMBL:AAF79567.1,
GN ECO:0000312|EMBL:AAF79568.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=15955925; DOI=10.1104/pp.104.054452;
RA Fritz-Laylin L.K., Krishnamurthy N., Toer M., Sjoelander K.V., Jones J.D.;
RT "Phylogenomic analysis of the receptor-like proteins of rice and
RT Arabidopsis.";
RL Plant Physiol. 138:611-623(2005).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18434605; DOI=10.1104/pp.108.119487;
RA Wang G., Ellendorff U., Kemp B., Mansfield J.W., Forsyth A., Mitchell K.,
RA Bastas K., Liu C.-M., Woods-Toer A., Zipfel C., de Wit P.J.G.M.,
RA Jones J.D.G., Toer M., Thomma B.P.H.J.;
RT "A genome-wide functional investigation into the roles of receptor-like
RT proteins in Arabidopsis.";
RL Plant Physiol. 147:503-517(2008).
RN [6]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=23898033; DOI=10.1105/tpc.113.110833;
RA Jehle A.K., Lipschis M., Albert M., Fallahzadeh-Mamaghani V., Fuerst U.,
RA Mueller K., Felix G.;
RT "The receptor-like protein ReMAX of Arabidopsis detects the microbe-
RT associated molecular pattern eMax from Xanthomonas.";
RL Plant Cell 25:2330-2340(2013).
RN [7]
RP FUNCTION.
RX PubMed=24384530; DOI=10.4161/psb.27408;
RA Jehle A.K., Fuerst U., Lipschis M., Albert M., Felix G.;
RT "Perception of the novel MAMP eMax from different Xanthomonas species
RT requires the Arabidopsis receptor-like protein ReMAX and the receptor
RT kinase SOBIR.";
RL Plant Signal. Behav. 8:E27408-E27408(2013).
RN [8]
RP REVIEW.
RX PubMed=25064074; DOI=10.1016/j.pbi.2014.07.007;
RA Gust A.A., Felix G.;
RT "Receptor like proteins associate with SOBIR1-type of adaptors to form
RT bimolecular receptor kinases.";
RL Curr. Opin. Plant Biol. 21:104-111(2014).
CC -!- FUNCTION: Involved in plant defense. Confers resistance to the
CC bacterial pathogen Xanthomonas through recognition of the microbe-
CC associated molecular pattern (MAMP) eMax (PubMed:23898033,
CC PubMed:24384530). Functionality seems to depend on the presence of the
CC receptor kinase SOBIR1 as an adapter protein (PubMed:24384530).
CC {ECO:0000269|PubMed:23898033, ECO:0000269|PubMed:24384530}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative initiation; Named isoforms=2;
CC Name=1;
CC IsoId=Q9LNV9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9LNV9-2; Sequence=VSP_059332;
CC -!- DISRUPTION PHENOTYPE: Lack of responsiveness to MAMP eMax from
CC Xanthomonas. {ECO:0000269|PubMed:23898033}.
CC -!- SIMILARITY: Belongs to the RLP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79567.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes.; Evidence={ECO:0000305};
CC Sequence=AAF79568.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes.; Evidence={ECO:0000305};
CC Sequence=BAE98877.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC022464; AAF79567.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC022464; AAF79568.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; ANM60456.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE28118.1; -; Genomic_DNA.
DR EMBL; AK226779; BAE98877.1; ALT_INIT; mRNA.
DR PIR; H86208; H86208.
DR RefSeq; NP_001154317.1; NM_001160845.2. [Q9LNV9-2]
DR RefSeq; NP_001322741.1; NM_001331697.1. [Q9LNV9-1]
DR AlphaFoldDB; Q9LNV9; -.
DR SMR; Q9LNV9; -.
DR STRING; 3702.AT1G07390.3; -.
DR iPTMnet; Q9LNV9; -.
DR PRIDE; Q9LNV9; -.
DR ProteomicsDB; 227994; -. [Q9LNV9-1]
DR EnsemblPlants; AT1G07390.2; AT1G07390.2; AT1G07390. [Q9LNV9-2]
DR EnsemblPlants; AT1G07390.4; AT1G07390.4; AT1G07390. [Q9LNV9-1]
DR GeneID; 837251; -.
DR Gramene; AT1G07390.2; AT1G07390.2; AT1G07390. [Q9LNV9-2]
DR Gramene; AT1G07390.4; AT1G07390.4; AT1G07390. [Q9LNV9-1]
DR KEGG; ath:AT1G07390; -.
DR Araport; AT1G07390; -.
DR PRO; PR:Q9LNV9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LNV9; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IDA:UniProtKB.
DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; -; 4.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF13855; LRR_8; 4.
DR Pfam; PF08263; LRRNT_2; 1.
DR SMART; SM00369; LRR_TYP; 11.
DR PROSITE; PS51450; LRR; 24.
PE 2: Evidence at transcript level;
KW Alternative initiation; Cell membrane; Glycoprotein; Immunity;
KW Innate immunity; Leucine-rich repeat; Membrane; Plant defense; Receptor;
KW Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..38
FT /evidence="ECO:0000255"
FT CHAIN 39..1077
FT /note="Receptor-like protein 1"
FT /id="PRO_0000443337"
FT TOPO_DOM 39..1024
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 1025..1045
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 1046..1077
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REPEAT 124..147
FT /note="LRR 1"
FT /evidence="ECO:0000255"
FT REPEAT 153..176
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 177..201
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 202..225
FT /note="LRR 4"
FT /evidence="ECO:0000255"
FT REPEAT 227..250
FT /note="LRR 5"
FT /evidence="ECO:0000255"
FT REPEAT 251..274
FT /note="LRR 6"
FT /evidence="ECO:0000255"
FT REPEAT 275..299
FT /note="LRR 7"
FT /evidence="ECO:0000255"
FT REPEAT 300..324
FT /note="LRR 8"
FT /evidence="ECO:0000255"
FT REPEAT 326..348
FT /note="LRR 9"
FT /evidence="ECO:0000255"
FT REPEAT 351..376
FT /note="LRR 10"
FT /evidence="ECO:0000255"
FT REPEAT 378..397
FT /note="LRR 11"
FT /evidence="ECO:0000255"
FT REPEAT 399..424
FT /note="LRR 12"
FT /evidence="ECO:0000255"
FT REPEAT 425..449
FT /note="LRR 13; degenerate"
FT /evidence="ECO:0000305"
FT REPEAT 450..473
FT /note="LRR 14"
FT /evidence="ECO:0000255"
FT REPEAT 474..498
FT /note="LRR 15"
FT /evidence="ECO:0000255"
FT REPEAT 499..522
FT /note="LRR 16"
FT /evidence="ECO:0000255"
FT REPEAT 524..545
FT /note="LRR 17"
FT /evidence="ECO:0000255"
FT REPEAT 546..570
FT /note="LRR 18"
FT /evidence="ECO:0000255"
FT REPEAT 572..594
FT /note="LRR 19"
FT /evidence="ECO:0000255"
FT REPEAT 595..621
FT /note="LRR 20"
FT /evidence="ECO:0000255"
FT REPEAT 623..643
FT /note="LRR 21"
FT /evidence="ECO:0000255"
FT REPEAT 644..666
FT /note="LRR 22"
FT /evidence="ECO:0000255"
FT REPEAT 667..694
FT /note="LRR 23"
FT /evidence="ECO:0000255"
FT REPEAT 696..713
FT /note="LRR 24"
FT /evidence="ECO:0000255"
FT REPEAT 714..737
FT /note="LRR 25"
FT /evidence="ECO:0000255"
FT REPEAT 739..761
FT /note="LRR 26"
FT /evidence="ECO:0000255"
FT REPEAT 762..785
FT /note="LRR 27"
FT /evidence="ECO:0000255"
FT REPEAT 786..808
FT /note="LRR 28"
FT /evidence="ECO:0000255"
FT REPEAT 877..901
FT /note="LRR 29"
FT /evidence="ECO:0000255"
FT REPEAT 902..925
FT /note="LRR 30"
FT /evidence="ECO:0000255"
FT REPEAT 927..949
FT /note="LRR 31"
FT /evidence="ECO:0000255"
FT REPEAT 951..970
FT /note="LRR 32"
FT /evidence="ECO:0000255"
FT REGION 39..120
FT /note="N-cap"
FT /evidence="ECO:0000305|PubMed:23898033"
FT REGION 971..1024
FT /note="C-cap/acidic domain"
FT /evidence="ECO:0000305|PubMed:23898033"
FT CARBOHYD 117
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 131
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 139
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 201
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 240
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 289
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 373
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 390
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 423
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 460
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 498
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 553
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 618
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 631
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 645
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 749
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 771
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 908
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 956
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 961
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT VAR_SEQ 1..164
FT /note="Missing (in isoform 2)"
FT /id="VSP_059332"
SQ SEQUENCE 1077 AA; 121495 MW; 024C256D27C888CF CRC64;
MRTDERRRWW VKPKKHITLV FITITMIIQF QMKGCVSCVE TERMGLLQLK SYLKNLVDAE
EEEEEGLSIL KSWTHHEGDC CRWERVKCSD AINGHVIGLS LDRLVPVAFE SQTRSLNLSL
LHSFPQLQSL NLSWNWFTNL SDHFLGFKSF GTLDKLTTLD FSHNMFDNSI VPFLNAATSI
RSLHLESNYM EGVFPPQELS NMTNLRVLNL KDNSFSFLSS QGLTDFRDLE VLDLSFNGVN
DSEASHSLST AKLKTLDLNF NPLSDFSQLK GLESLQELQV LKLRGNKFNH TLSTHVLKDL
KMLQELDLSD NGFTNLDHGR GLEIPTSLQV LDFKRNQLSL THEGYLGICR LMKLRELDLS
SNALTSLPYC LGNLTHLRTL DLSNNQLNGN LSSFVSGLPS VLEYLSLLDN NFDGSFLFNS
LVNQTRLTVF KLSSKVGVIQ VQTESSWAPL FQLKMLYLSN CSLGSTMLGF LVHQRDLCFV
DLSHNKLTGT FPTWLVKNNT RLQTILLSGN SLTKLQLPIL VHGLQVLDIS SNMIYDSIQE
DIGMVFPNLR FMNFSSNHFQ GTIPSSIGEM KSLQVLDMSS NGLYGQLPIM FLSGCYSLRV
LKLSNNQLQG KIFSKHANLT GLVGLFLDGN NFTGSLEEGL LKSKNLTLLD ISDNRFSGML
PLWIGRISRL SYLYMSGNQL KGPFPFLRQS PWVEVMDISH NSFSGSIPRN VNFPSLRELR
LQNNEFTGLV PGNLFKAAGL EVLDLRNNNF SGKILNTIDQ TSKLRILLLR NNSFQTYIPG
KICQLSEVGL LDLSHNQFRG PIPSCFSKMS FGAEQNDRTM SLVADFDFSY ITFLPHCQYG
SHLNLDDGVR NGYQPKPATV VDFLTKSRYE AYQGDILRYM HGLDLSSNEL SGEIPIEIGD
LQNIRSLNLS SNRLTGSIPD SISKLKGLES LDLSNNKLDG SIPPALADLN SLGYLNISYN
NLSGEIPFKG HLVTFDERSY IGNAHLCGLP TNKNCISQRV PEPPSVSTHA KEEENEEEGN
VIDMVWFYWT CAAVYISTSL ALFAFLYIDS RWSREWFYRV DLCVHHILQF KRSSVCN
