RLP21_ARATH
ID RLP21_ARATH Reviewed; 978 AA.
AC Q9SKK2; A0A1P8B265;
DT 28-MAR-2018, integrated into UniProtKB/Swiss-Prot.
DT 28-MAR-2018, sequence version 2.
DT 25-MAY-2022, entry version 126.
DE RecName: Full=Receptor like protein 21 {ECO:0000303|PubMed:18434605};
DE Short=AtRLP21 {ECO:0000303|PubMed:18434605};
DE Flags: Precursor;
GN Name=RLP21 {ECO:0000303|PubMed:18434605};
GN OrderedLocusNames=At2g25470 {ECO:0000312|Araport:AT2G25470};
GN ORFNames=F13B15.13 {ECO:0000312|EMBL:AAD20706.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=15955925; DOI=10.1104/pp.104.054452;
RA Fritz-Laylin L.K., Krishnamurthy N., Toer M., Sjoelander K.V., Jones J.D.;
RT "Phylogenomic analysis of the receptor-like proteins of rice and
RT Arabidopsis.";
RL Plant Physiol. 138:611-623(2005).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18434605; DOI=10.1104/pp.108.119487;
RA Wang G., Ellendorff U., Kemp B., Mansfield J.W., Forsyth A., Mitchell K.,
RA Bastas K., Liu C.-M., Woods-Toer A., Zipfel C., de Wit P.J.G.M.,
RA Jones J.D.G., Toer M., Thomma B.P.H.J.;
RT "A genome-wide functional investigation into the roles of receptor-like
RT proteins in Arabidopsis.";
RL Plant Physiol. 147:503-517(2008).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RLP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD20706.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006300; AAD20706.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; ANM62952.1; -; Genomic_DNA.
DR PIR; G84648; G84648.
DR RefSeq; NP_001325073.1; NM_001335999.1.
DR AlphaFoldDB; Q9SKK2; -.
DR SMR; Q9SKK2; -.
DR STRING; 3702.AT2G25470.1; -.
DR EnsemblPlants; AT2G25470.3; AT2G25470.3; AT2G25470.
DR GeneID; 817085; -.
DR Gramene; AT2G25470.3; AT2G25470.3; AT2G25470.
DR KEGG; ath:AT2G25470; -.
DR Araport; AT2G25470; -.
DR OrthoDB; 826997at2759; -.
DR PhylomeDB; Q9SKK2; -.
DR PRO; PR:Q9SKK2; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SKK2; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.80.10.10; -; 6.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR SMART; SM00369; LRR_TYP; 12.
DR PROSITE; PS51450; LRR; 19.
PE 3: Inferred from homology;
KW Cell membrane; Glycoprotein; Leucine-rich repeat; Membrane; Receptor;
KW Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..978
FT /note="Receptor like protein 21"
FT /id="PRO_5010159029"
FT TOPO_DOM 28..930
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 931..951
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 952..978
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REPEAT 141..167
FT /note="LRR 1"
FT /evidence="ECO:0000255"
FT REPEAT 169..189
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 190..213
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 214..237
FT /note="LRR 4"
FT /evidence="ECO:0000255"
FT REPEAT 238..262
FT /note="LRR 5"
FT /evidence="ECO:0000255"
FT REPEAT 264..287
FT /note="LRR 6"
FT /evidence="ECO:0000255"
FT REPEAT 288..310
FT /note="LRR 7"
FT /evidence="ECO:0000255"
FT REPEAT 312..335
FT /note="LRR 8"
FT /evidence="ECO:0000255"
FT REPEAT 337..361
FT /note="LRR 9"
FT /evidence="ECO:0000255"
FT REPEAT 362..385
FT /note="LRR 10"
FT /evidence="ECO:0000255"
FT REPEAT 386..409
FT /note="LRR 11"
FT /evidence="ECO:0000255"
FT REPEAT 410..432
FT /note="LRR 12"
FT /evidence="ECO:0000255"
FT REPEAT 433..455
FT /note="LRR 13"
FT /evidence="ECO:0000255"
FT REPEAT 457..480
FT /note="LRR 14"
FT /evidence="ECO:0000255"
FT REPEAT 481..504
FT /note="LRR 15"
FT /evidence="ECO:0000255"
FT REPEAT 506..529
FT /note="LRR 16"
FT /evidence="ECO:0000255"
FT REPEAT 530..553
FT /note="LRR 17"
FT /evidence="ECO:0000255"
FT REPEAT 554..577
FT /note="LRR 18"
FT /evidence="ECO:0000255"
FT REPEAT 579..601
FT /note="LRR 19"
FT /evidence="ECO:0000255"
FT REPEAT 602..625
FT /note="LRR 20"
FT /evidence="ECO:0000255"
FT REPEAT 627..646
FT /note="LRR 21"
FT /evidence="ECO:0000255"
FT REPEAT 647..671
FT /note="LRR 22"
FT /evidence="ECO:0000255"
FT REPEAT 673..693
FT /note="LRR 23"
FT /evidence="ECO:0000255"
FT REPEAT 694..716
FT /note="LRR 24"
FT /evidence="ECO:0000255"
FT REPEAT 788..811
FT /note="LRR 25"
FT /evidence="ECO:0000255"
FT REPEAT 812..835
FT /note="LRR 26"
FT /evidence="ECO:0000255"
FT REPEAT 837..859
FT /note="LRR 27"
FT /evidence="ECO:0000255"
FT REPEAT 860..885
FT /note="LRR 28"
FT /evidence="ECO:0000255"
FT REGION 902..922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 64
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 79
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 102
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 116
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 155
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 204
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 335
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 397
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 420
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 463
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 482
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 492
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 552
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 636
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 681
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 716
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 819
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 872
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 978 AA; 109593 MW; 21ED68739D387710 CRC64;
MLLAMEGKLF LCQYLIWVML LLGQLHGCTS CIEKEREALL ELKKYLMSRS RESGLDYVLP
TWTNDTKSDC CQWDGIKCNR TSGRVIELSV GDMYFKESSP LNLSLLHPFE EVRSLNLSTE
GYNEFNGFFD DVEGYRSLSG LRNLKIMDLS TNYFNYSTFP FLNAATSLTT LILTYNEMDG
PFPIKGLKDL TNLELLDLRA NKLNGSMQEL IHLKKLKALD LSSNKFSSSM ELQELQNLIN
LEVLGLAQNH VDGPIPIEVF CKLKNLRDLD LKGNHFVGQI PLCLGSLKKL RVLDLSSNQL
SGDLPSSFSS LESLEYLSLS DNNFDGSFSL NPLTNLTNLK LFKLSSRSHT IQVKMESTWQ
PNFQLSVVVL RFCSLEKIPS FLLYQKKLRL VDLSSNNLSG NIPTWLLTNN PELEVLQLQN
NSFTIFPIPT MVHNLQIFDF SANNIGKFPD KMDHALPNLV RLNGSNNGFQ GYFPTSIGEM
KNISFLDLSY NNFSGKLPRS FVTGCVSIMF LKLSHNKFSG RFLPRETNFP SLDVLRMDNN
LFTGNIGGGL SNSTMLRILD MSNNGLSGAI PRWLFEFPYL DYVLISNNFL EGTIPPSLLG
MPFLSFLDLS GNQFSGALPS HVDSELGIYM FLHNNNFTGP IPDTLLKSVQ ILDLRNNKLS
GSIPQFDDTQ SINILLLKGN NLTGSIPREL CDLSNVRLLD LSDNKLNGVI PSCLSNLSFG
RLQEDAMALN IPPSFLQTSL EMELYKSTFL VDKIEVDRST YQETEIKFAA KQRYDSYSGR
SEFSEGILRL MYGMDLSNNE LSGVIPTELG DLLKLRTLNL SHNSLLGSIP SSFSKLIDVE
SLDLSHNMLQ GSIPQLLSSL TSLAVFDVSS NNLSGIIPQG RQFNTFEEES YLGNPLLCGP
PTSRSCETNK SPEEADNGQE EEDDKAAIDM MVFYFSTASI YVTALIGVLV LMCFDCPWRR
AWLRIVDAFI ASAKHVLP
