RLP22_ARATH
ID RLP22_ARATH Reviewed; 771 AA.
AC O48851; Q0WRZ8; Q84WI9;
DT 28-MAR-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Receptor like protein 22 {ECO:0000303|PubMed:18434605};
DE Short=AtRLP22 {ECO:0000303|PubMed:18434605};
DE Flags: Precursor;
GN Name=RLP22 {ECO:0000303|PubMed:18434605};
GN OrderedLocusNames=At2g32660 {ECO:0000312|Araport:AT2G32660};
GN ORFNames=F24L7.20 {ECO:0000312|EMBL:AAC04497.1},
GN T26B15 {ECO:0000312|EMBL:AAM14989.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 35-771.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 183-771.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=15955925; DOI=10.1104/pp.104.054452;
RA Fritz-Laylin L.K., Krishnamurthy N., Toer M., Sjoelander K.V., Jones J.D.;
RT "Phylogenomic analysis of the receptor-like proteins of rice and
RT Arabidopsis.";
RL Plant Physiol. 138:611-623(2005).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18434605; DOI=10.1104/pp.108.119487;
RA Wang G., Ellendorff U., Kemp B., Mansfield J.W., Forsyth A., Mitchell K.,
RA Bastas K., Liu C.-M., Woods-Toer A., Zipfel C., de Wit P.J.G.M.,
RA Jones J.D.G., Toer M., Thomma B.P.H.J.;
RT "A genome-wide functional investigation into the roles of receptor-like
RT proteins in Arabidopsis.";
RL Plant Physiol. 147:503-517(2008).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RLP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AEC08713.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAF00101.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC003974; AAC04497.1; -; Genomic_DNA.
DR EMBL; AC004681; AAM14989.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08713.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002685; ANM61731.1; -; Genomic_DNA.
DR EMBL; AK228145; BAF00101.1; ALT_INIT; mRNA.
DR EMBL; BT003164; AAO24596.1; -; mRNA.
DR PIR; T02565; T02565.
DR RefSeq; NP_001323933.1; NM_001336409.1.
DR RefSeq; NP_180825.2; NM_128825.3.
DR AlphaFoldDB; O48851; -.
DR SMR; O48851; -.
DR STRING; 3702.AT2G32660.1; -.
DR PRIDE; O48851; -.
DR ProteomicsDB; 227981; -.
DR EnsemblPlants; AT2G32660.2; AT2G32660.2; AT2G32660.
DR GeneID; 817826; -.
DR Gramene; AT2G32660.2; AT2G32660.2; AT2G32660.
DR KEGG; ath:AT2G32660; -.
DR Araport; AT2G32660; -.
DR TAIR; locus:2046397; AT2G32660.
DR eggNOG; KOG0619; Eukaryota.
DR OMA; FHINAPT; -.
DR OrthoDB; 351526at2759; -.
DR PRO; PR:O48851; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O48851; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.80.10.10; -; 4.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR045273; RLP23-like.
DR PANTHER; PTHR27004; PTHR27004; 1.
DR Pfam; PF13516; LRR_6; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00369; LRR_TYP; 9.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; Leucine-rich repeat; Membrane; Receptor;
KW Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..771
FT /note="Receptor like protein 22"
FT /id="PRO_5013530149"
FT TOPO_DOM 21..729
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 730..750
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 751..771
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REPEAT 86..110
FT /note="LRR 1"
FT /evidence="ECO:0000255"
FT REPEAT 112..135
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 136..159
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 160..183
FT /note="LRR 4"
FT /evidence="ECO:0000255"
FT REPEAT 185..206
FT /note="LRR 5"
FT /evidence="ECO:0000255"
FT REPEAT 207..230
FT /note="LRR 6"
FT /evidence="ECO:0000255"
FT REPEAT 232..254
FT /note="LRR 7"
FT /evidence="ECO:0000255"
FT REPEAT 255..281
FT /note="LRR 8"
FT /evidence="ECO:0000255"
FT REPEAT 283..303
FT /note="LRR 9"
FT /evidence="ECO:0000255"
FT REPEAT 304..327
FT /note="LRR 10"
FT /evidence="ECO:0000255"
FT REPEAT 329..350
FT /note="LRR 11"
FT /evidence="ECO:0000255"
FT REPEAT 353..377
FT /note="LRR 12"
FT /evidence="ECO:0000255"
FT REPEAT 378..397
FT /note="LRR 13; degenerate"
FT /evidence="ECO:0000305"
FT REPEAT 398..419
FT /note="LRR 14"
FT /evidence="ECO:0000255"
FT REPEAT 420..443
FT /note="LRR 15"
FT /evidence="ECO:0000255"
FT REPEAT 445..467
FT /note="LRR 16"
FT /evidence="ECO:0000255"
FT REPEAT 469..491
FT /note="LRR 17"
FT /evidence="ECO:0000255"
FT REPEAT 492..516
FT /note="LRR 18"
FT /evidence="ECO:0000255"
FT REPEAT 519..543
FT /note="LRR 19"
FT /evidence="ECO:0000255"
FT REPEAT 588..612
FT /note="LRR 20"
FT /evidence="ECO:0000255"
FT REPEAT 613..636
FT /note="LRR 21"
FT /evidence="ECO:0000255"
FT REPEAT 637..660
FT /note="LRR 22"
FT /evidence="ECO:0000255"
FT REPEAT 662..685
FT /note="LRR 23"
FT /evidence="ECO:0000255"
FT CARBOHYD 46
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 58
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 80
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 93
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 134
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 158
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 204
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 242
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 292
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 337
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 344
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 353
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 379
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 384
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 397
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 410
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 421
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 466
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 481
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 543
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 619
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 622
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 635
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CONFLICT 430
FT /note="N -> S (in Ref. 4; AAO24596)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 771 AA; 85762 MW; B61D59E9D091497A CRC64;
MSNLRLRLLS LVSILYCIAA LRCRPDQTET IKRFKNEFAF SSICRNDTNF FSGVVCDNTT
GAVTVLELPG GCLRGTLRPN SSLFELSHLR YLNLSFNNFD SSPLSSAFGQ LNNLEVLLLS
SNGFTGQVPS SIRNLTKLTQ LNLPHNKLTG DLPSLVQNLT KLLALDLSYN QFSGTIPSSF
FTMPFLSYLD LSENHLTGSF EISNSSSKLE NLNLGNNHFE TEIIDPVLRL VNLRYLSLSF
LNTSHPIDLS IFSPLQSLTH LDLHGNSLTL TSVYSDIDFP KNMEILLLSG CNISEFPRFL
KSLKKLWYLD LSSNRIKGNV PDWIWSLPLL VSLDLSNNSF TGFNGSLDHV LANSSVQVLD
IALNSFKGSF PNPPVSIINL SAWNNSFTGD IPLSVCNRTS LDVLDLSYNN FTGSIPPCMG
NFTIVNLRKN KLEGNIPDEF YSGALTQTLD VGYNQLTGEL PRSLLNCSFI RFLSVDHNRI
NDSFPLWLKA LPNLKVLTLR SNSFHGPMSP PDDQSSLAFP KLQILEISHN RFTGSLPTNY
FANWSVKSLK MYDEERLYMG DYSSDRFVYE DTLDLQYKGL YMEQGKVLTF YSAIDFSGNK
LEGEIPESIG LLKTLIALNL SNNSFTGHIP MSFANVTELE SLDLSGNKLS GEIPQELGRL
SYLAYIDVSD NQLTGKIPQG TQIIGQPKSS FEGNSGLCGL PLEESCLRED APSTQEPEEE
EEEILEWRAA AIGYGPGVLF GLAIGHVVAL YKPGWFIKNN GQNRLRGIRH P
