RLP4_ARATH
ID RLP4_ARATH Reviewed; 626 AA.
AC F4HWL3; Q9SGN1;
DT 28-FEB-2018, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Receptor-like protein 4 {ECO:0000303|PubMed:18434605};
DE Short=AtRLP4 {ECO:0000303|PubMed:18434605};
DE Flags: Precursor;
GN Name=RLP4 {ECO:0000303|PubMed:18434605};
GN OrderedLocusNames=At1g28340 {ECO:0000312|Araport:AT1G28340};
GN ORFNames=F3M18.23 {ECO:0000312|EMBL:AAF16758.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 487-626.
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=15955925; DOI=10.1104/pp.104.054452;
RA Fritz-Laylin L.K., Krishnamurthy N., Toer M., Sjoelander K.V., Jones J.D.;
RT "Phylogenomic analysis of the receptor-like proteins of rice and
RT Arabidopsis.";
RL Plant Physiol. 138:611-623(2005).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18434605; DOI=10.1104/pp.108.119487;
RA Wang G., Ellendorff U., Kemp B., Mansfield J.W., Forsyth A., Mitchell K.,
RA Bastas K., Liu C.-M., Woods-Toer A., Zipfel C., de Wit P.J.G.M.,
RA Jones J.D.G., Toer M., Thomma B.P.H.J.;
RT "A genome-wide functional investigation into the roles of receptor-like
RT proteins in Arabidopsis.";
RL Plant Physiol. 147:503-517(2008).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RLP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF16758.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC010155; AAF16758.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE30960.1; -; Genomic_DNA.
DR EMBL; BX816806; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_174156.1; NM_102600.2.
DR AlphaFoldDB; F4HWL3; -.
DR SMR; F4HWL3; -.
DR STRING; 3702.AT1G28340.1; -.
DR PaxDb; F4HWL3; -.
DR PRIDE; F4HWL3; -.
DR ProteomicsDB; 228009; -.
DR EnsemblPlants; AT1G28340.1; AT1G28340.1; AT1G28340.
DR GeneID; 839730; -.
DR Gramene; AT1G28340.1; AT1G28340.1; AT1G28340.
DR KEGG; ath:AT1G28340; -.
DR Araport; AT1G28340; -.
DR TAIR; locus:2032221; AT1G28340.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_000288_41_5_1; -.
DR InParanoid; F4HWL3; -.
DR OMA; YSVRVFF; -.
DR OrthoDB; 398783at2759; -.
DR PRO; PR:F4HWL3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4HWL3; baseline and differential.
DR GO; GO:0005768; C:endosome; HDA:TAIR.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005802; C:trans-Golgi network; HDA:TAIR.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR024788; Malectin-like_Carb-bd_dom.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF12819; Malectin_like; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; Leucine-rich repeat; Membrane; Receptor;
KW Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..626
FT /note="Receptor-like protein 4"
FT /id="PRO_5003316177"
FT TOPO_DOM 23..549
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 550..570
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 571..626
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REPEAT 420..444
FT /note="LRR 1"
FT /evidence="ECO:0000255"
FT REPEAT 445..468
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 470..492
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 493..516
FT /note="LRR 4"
FT /evidence="ECO:0000255"
FT REGION 603..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 61
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 282
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 333
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 417
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 451
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 482
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 524
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 626 AA; 68419 MW; 81621C0604EF7946 CRC64;
MMLRFILASL LLSSFSLYSS LARPAPYALR ISCGARKNVR TPPTYALWFK DIAYTGGVPA
NATTPTYITP PLKTLRYFPI SEGPNNCYNI VRVPKGHYSV RIFFGLVDQP SFDKEPLFDI
SIEGTQISSL KSGWSSQDDQ VFAEALIFLL GGTATICFHS TGHGDPAILS IEILQVDDKA
YSFGEGWGQG VILRTATRLT CGTGKSRFDE DYRGDHWGGD RFWNRMRSFG KSADSPRSTE
ETIKKASVSP NFYPEGLYQS ALVSTDDQPD LTYSLDVEPN RNYSVWLHFA EIDNTITAEG
KRVFDVVING DTFFEDVDII KMSGGRYAAL VLNATVTVSG RTLTVVLQPK AGGHAIINAI
EVFEIITAEF KTLRDEVSAL QKMKKALGLP SRFGWNGDPC VPPQHPWSGA NCQLDKNTSR
WFIDGLDLDN QGLKGFLPND ISKLKHLQSI NLSENNIRGG IPASLGSVTS LEVLDLSYNS
FNGSIPETLG ELTSLRILNL NGNSLSGKVP AAVGGRLLHR ASFNFTDNAG LCGIPGLPAC
GPHLSSGAKI GIAFGVSLAF LLIVACAMIW WKRRQNILRA QQIAARGAPY AKKRTHVSHD
IQMSRHGHNN HGQARTAVEN GPSLLS
