RLP53_ARATH
ID RLP53_ARATH Reviewed; 957 AA.
AC Q9S9U3; A0A1R7T3K3;
DT 23-MAY-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 157.
DE RecName: Full=Receptor-like protein 53 {ECO:0000303|PubMed:18434605};
DE Short=AtRLP53 {ECO:0000303|PubMed:18434605};
DE Flags: Precursor;
GN Name=RLP53 {ECO:0000303|PubMed:18434605};
GN OrderedLocusNames=At5g27060 {ECO:0000312|Araport:AT5G27060};
GN ORFNames=F15P11.4 {ECO:0000312|EMBL:AAD48937.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=15955925; DOI=10.1104/pp.104.054452;
RA Fritz-Laylin L.K., Krishnamurthy N., Toer M., Sjoelander K.V., Jones J.D.;
RT "Phylogenomic analysis of the receptor-like proteins of rice and
RT Arabidopsis.";
RL Plant Physiol. 138:611-623(2005).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=18434605; DOI=10.1104/pp.108.119487;
RA Wang G., Ellendorff U., Kemp B., Mansfield J.W., Forsyth A., Mitchell K.,
RA Bastas K., Liu C.-M., Woods-Toer A., Zipfel C., de Wit P.J.G.M.,
RA Jones J.D.G., Toer M., Thomma B.P.H.J.;
RT "A genome-wide functional investigation into the roles of receptor-like
RT proteins in Arabidopsis.";
RL Plant Physiol. 147:503-517(2008).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9S9U3-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9S9U3-2; Sequence=VSP_059574;
CC -!- SIMILARITY: Belongs to the RLP family. {ECO:0000305}.
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DR EMBL; AF160760; AAD48937.1; -; Genomic_DNA.
DR EMBL; CP002688; AED93645.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM71208.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM71209.1; -; Genomic_DNA.
DR RefSeq; NP_001318660.1; NM_001343990.1. [Q9S9U3-1]
DR RefSeq; NP_001332753.1; NM_001343991.1. [Q9S9U3-2]
DR RefSeq; NP_198058.1; NM_122588.1. [Q9S9U3-1]
DR AlphaFoldDB; Q9S9U3; -.
DR SMR; Q9S9U3; -.
DR IntAct; Q9S9U3; 5.
DR STRING; 3702.AT5G27060.1; -.
DR PaxDb; Q9S9U3; -.
DR PRIDE; Q9S9U3; -.
DR EnsemblPlants; AT5G27060.1; AT5G27060.1; AT5G27060. [Q9S9U3-1]
DR EnsemblPlants; AT5G27060.2; AT5G27060.2; AT5G27060. [Q9S9U3-2]
DR EnsemblPlants; AT5G27060.3; AT5G27060.3; AT5G27060. [Q9S9U3-1]
DR GeneID; 832764; -.
DR Gramene; AT5G27060.1; AT5G27060.1; AT5G27060. [Q9S9U3-1]
DR Gramene; AT5G27060.2; AT5G27060.2; AT5G27060. [Q9S9U3-2]
DR Gramene; AT5G27060.3; AT5G27060.3; AT5G27060. [Q9S9U3-1]
DR KEGG; ath:AT5G27060; -.
DR Araport; AT5G27060; -.
DR TAIR; locus:2144392; AT5G27060.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_000288_18_3_1; -.
DR InParanoid; Q9S9U3; -.
DR OMA; LCELFEL; -.
DR OrthoDB; 826997at2759; -.
DR PhylomeDB; Q9S9U3; -.
DR PRO; PR:Q9S9U3; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9S9U3; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.80.10.10; -; 3.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR045273; RLP23-like.
DR PANTHER; PTHR27004; PTHR27004; 3.
DR Pfam; PF00560; LRR_1; 3.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR SMART; SM00369; LRR_TYP; 8.
DR PROSITE; PS51450; LRR; 18.
PE 3: Inferred from homology;
KW Alternative splicing; Cell membrane; Glycoprotein; Leucine-rich repeat;
KW Membrane; Receptor; Reference proteome; Repeat; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..30
FT /evidence="ECO:0000255"
FT CHAIN 31..957
FT /note="Receptor-like protein 53"
FT /id="PRO_5014108341"
FT TOPO_DOM 31..910
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 911..931
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 932..957
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REPEAT 120..143
FT /note="LRR 1"
FT /evidence="ECO:0000255"
FT REPEAT 144..170
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 172..192
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 193..216
FT /note="LRR 4"
FT /evidence="ECO:0000255"
FT REPEAT 217..240
FT /note="LRR 5"
FT /evidence="ECO:0000255"
FT REPEAT 241..266
FT /note="LRR 6"
FT /evidence="ECO:0000255"
FT REPEAT 268..287
FT /note="LRR 7"
FT /evidence="ECO:0000255"
FT REPEAT 288..312
FT /note="LRR 8"
FT /evidence="ECO:0000255"
FT REPEAT 313..336
FT /note="LRR 9"
FT /evidence="ECO:0000255"
FT REPEAT 338..360
FT /note="LRR 10"
FT /evidence="ECO:0000255"
FT REPEAT 361..384
FT /note="LRR 11"
FT /evidence="ECO:0000255"
FT REPEAT 386..409
FT /note="LRR 12"
FT /evidence="ECO:0000255"
FT REPEAT 412..433
FT /note="LRR 13; degenerate"
FT /evidence="ECO:0000305"
FT REPEAT 434..458
FT /note="LRR 14"
FT /evidence="ECO:0000255"
FT REPEAT 460..483
FT /note="LRR 15"
FT /evidence="ECO:0000255"
FT REPEAT 486..509
FT /note="LRR 16"
FT /evidence="ECO:0000255"
FT REPEAT 510..533
FT /note="LRR 17"
FT /evidence="ECO:0000255"
FT REPEAT 535..556
FT /note="LRR 18"
FT /evidence="ECO:0000255"
FT REPEAT 558..580
FT /note="LRR 19"
FT /evidence="ECO:0000255"
FT REPEAT 581..604
FT /note="LRR 20"
FT /evidence="ECO:0000255"
FT REPEAT 605..629
FT /note="LRR 21"
FT /evidence="ECO:0000255"
FT REPEAT 631..651
FT /note="LRR 22"
FT /evidence="ECO:0000255"
FT REPEAT 652..674
FT /note="LRR 23"
FT /evidence="ECO:0000255"
FT REPEAT 675..697
FT /note="LRR 24"
FT /evidence="ECO:0000255"
FT REPEAT 698..721
FT /note="LRR 25"
FT /evidence="ECO:0000255"
FT REPEAT 765..789
FT /note="LRR 26"
FT /evidence="ECO:0000255"
FT REPEAT 790..813
FT /note="LRR 27"
FT /evidence="ECO:0000255"
FT REPEAT 814..837
FT /note="LRR 28"
FT /evidence="ECO:0000255"
FT REPEAT 839..862
FT /note="LRR 29"
FT /evidence="ECO:0000255"
FT CARBOHYD 78
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 114
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 143
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 167
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 191
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 239
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 242
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 252
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 263
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 311
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 332
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 381
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 441
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 446
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 477
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 540
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 543
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 594
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 665
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 711
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 812
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 844
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 864
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT VAR_SEQ 1
FT /note="M -> MM (in isoform 2)"
FT /id="VSP_059574"
SQ SEQUENCE 957 AA; 106675 MW; 0B05553E992A9543 CRC64;
MEGFWNSKSI IRITLSFIFL FICHFLDVLA APTRNLCRPE QRDALLAFKN EFEIGKPSPD
HCKIYGIESP RKTDSWGNNS DCCNWEGVTC NAKSGEVIEL DLSCSSLHGR FHSNSSIRNL
HFLTTLDLSF NDFKGQITSS IENLSHLTYL DLSSNHFSGQ ILNSIGNLSR LTYLNLFDNQ
FSGQAPSSIC NLSHLTFLDL SYNRFFGQFP SSIGGLSHLT TLSLFSNKFS GQIPSSIGNL
SNLTTLDLSN NNFSGQIPSF IGNLSQLTFL GLFSNNFVGE IPSSFGNLNQ LTRLYVDDNK
LSGNFPNVLL NLTGLSLLSL SNNKFTGTLP PNITSLSNLM DFDASDNAFT GTFPSFLFTI
PSLTYIRLNG NQLKGTLEFG NISSPSNLYE LDIGNNNFIG PIPSSISKLV KLFRLDISHL
NTQGPVDFSI FSHLKSLLDL NISHLNTTTR IDLNYFLSYF KRLLLLDLSG NHVSATNKSS
VSDPPSQLIQ SLYLSGCGIT EFPEFVRTQH ELGFLDISNN KIKGQVPDWL WRLPILYYVN
LSNNTLIGFQ RPSKPEPSLL YLLGSNNNFI GKIPSFICGL RSLNTLDLSD NNFNGSIPRC
MGHLKSTLSV LNLRQNHLSG GLPKQIFEIL RSLDVGHNQL VGKLPRSLSF FSTLEVLNVE
SNRINDTFPF WLSSLPKLQV LVLRSNAFHG PIHEATFPEL RIIDISHNRF NGTLPTEYFV
KWSAMSSLGK NEDQSNEKYM GSGLYYQDSM VLMNKGVAME LVRILTIYTA VDFSGNRFEG
EIPKSIGLLK ELLVLSLSNN AFSGHMPSSM GNLTALESLD VSKNKLTGEI PQELGDLSFL
AYMNFSHNQL AGLVPGGQQF LTQNCSAFED NLGLFGSSLE EVCRDIHTPA SHQQFETPET
EEEDEDLISW IAAAIGFGPG IAFGLMFGYI LVSYKPEWFM NPFDRNNRRQ KRHKTTH
