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RLP7_KLULA
ID   RLP7_KLULA              Reviewed;         318 AA.
AC   P32102; Q6CS12;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2004, sequence version 2.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Ribosome biogenesis protein RLP7;
GN   Name=RLP7; OrderedLocusNames=KLLA0D04884g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 136-318.
RC   STRAIN=ATCC 76492 / CBS 2359/152 / CLIB 210;
RX   PubMed=1441757; DOI=10.1002/yea.320080914;
RA   Zhang Y.-P., Chen X.J., Li Y.Y., Fukuhara H.;
RT   "LEU2 gene homolog in Kluyveromyces lactis.";
RL   Yeast 8:801-804(1992).
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit. May
CC       act as a specificity factor that binds precursor rRNAs and tethers the
CC       enzymes that carry out the early 5' to 3' exonucleolytic reactions that
CC       generate the mature rRNAs (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL30 family.
CC       {ECO:0000305}.
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DR   EMBL; CR382124; CAH00373.1; -; Genomic_DNA.
DR   EMBL; X65545; CAA46513.1; -; Genomic_DNA.
DR   PIR; S25368; S25368.
DR   RefSeq; XP_453277.1; XM_453277.1.
DR   AlphaFoldDB; P32102; -.
DR   SMR; P32102; -.
DR   STRING; 28985.XP_453277.1; -.
DR   EnsemblFungi; CAH00373; CAH00373; KLLA0_D04884g.
DR   GeneID; 2892740; -.
DR   KEGG; kla:KLLA0_D04884g; -.
DR   eggNOG; KOG3184; Eukaryota.
DR   HOGENOM; CLU_055156_1_0_1; -.
DR   InParanoid; P32102; -.
DR   OMA; CMEDIIH; -.
DR   Proteomes; UP000000598; Chromosome D.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IEA:EnsemblFungi.
DR   GO; GO:0042134; F:rRNA primary transcript binding; IEA:EnsemblFungi.
DR   GO; GO:0000465; P:exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   CDD; cd01657; Ribosomal_L7_archeal_euk; 1.
DR   Gene3D; 3.30.1390.20; -; 1.
DR   InterPro; IPR036919; L30_ferredoxin-like_sf.
DR   InterPro; IPR018038; Ribosomal_L30_CS.
DR   InterPro; IPR016082; Ribosomal_L30_ferredoxin-like.
DR   InterPro; IPR039699; Ribosomal_L7/L30.
DR   InterPro; IPR035808; Ribosomal_L7_euk_arc.
DR   PANTHER; PTHR11524; PTHR11524; 1.
DR   Pfam; PF00327; Ribosomal_L30; 1.
DR   SUPFAM; SSF55129; SSF55129; 1.
DR   PROSITE; PS00634; RIBOSOMAL_L30; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding.
FT   CHAIN           1..318
FT                   /note="Ribosome biogenesis protein RLP7"
FT                   /id="PRO_0000104656"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          101..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        13..49
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   318 AA;  36587 MW;  A684E7F83DA42117 CRC64;
     MSQPLNSNPE VLLRKRRNAD RTRLEKQELA KKRKEQEEKQ KRSKKNRFVR AETIVATTLA
     TEREKTRIRR VRDLENQKVK NDLSHIPSDR DFILRISERE AGSKATSESE LQDVDEEDEE
     DDGLIREKIV YDGEPSLLFV IRVKGPTAVK IPAKAYKVLS LLRLVELNTG VFIKLTKDVY
     PLLKLVSPYI VIGQPSLASI RSLIQKRSRI MWQRPEDKEP KEIILNDNNI VEEKLGDEGV
     ICIEDIIHEI STLGENFSKC TFFLLPFKLN REVSGFGAIS RLNKLKMREQ NKKTRQISNA
     ATAPVIQVDI DSMISKLN
 
 
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