RLP8X_ARATH
ID RLP8X_ARATH Reviewed; 1009 AA.
AC Q9SLI6; A0A1P8ANW0; Q3ECQ0;
DT 28-FEB-2018, integrated into UniProtKB/Swiss-Prot.
DT 28-FEB-2018, sequence version 2.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Putative receptor-like protein 8 {ECO:0000305};
DE Short=AtRLP8 {ECO:0000305};
DE Flags: Precursor;
GN Name=RLP8 {ECO:0000305};
GN OrderedLocusNames=At1g54470/At1g54475 {ECO:0000312|Araport:AT1G54470};
GN ORFNames=F20D21.29 {ECO:0000312|EMBL:AAD25626.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=20565641; DOI=10.1111/j.1364-3703.2004.00264.x;
RA Kruijt M., de Kock M.J., de Wit P.J.;
RT "Receptor-like proteins involved in plant disease resistance.";
RL Mol. Plant Pathol. 6:85-97(2005).
RN [4]
RP GENE FAMILY.
RX PubMed=15955925; DOI=10.1104/pp.104.054452;
RA Fritz-Laylin L.K., Krishnamurthy N., Toer M., Sjoelander K.V., Jones J.D.;
RT "Phylogenomic analysis of the receptor-like proteins of rice and
RT Arabidopsis.";
RL Plant Physiol. 138:611-623(2005).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18434605; DOI=10.1104/pp.108.119487;
RA Wang G., Ellendorff U., Kemp B., Mansfield J.W., Forsyth A., Mitchell K.,
RA Bastas K., Liu C.-M., Woods-Toer A., Zipfel C., de Wit P.J.G.M.,
RA Jones J.D.G., Toer M., Thomma B.P.H.J.;
RT "A genome-wide functional investigation into the roles of receptor-like
RT proteins in Arabidopsis.";
RL Plant Physiol. 147:503-517(2008).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RLP family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. In strain cv. Columbia,
CC a naturally occurring variation results in the deletion of 35 amino
CC acids in the middle part of the protein. Lacks part of the
CC extracellular leucine-rich repeats that are required for the
CC specificity of the elicitor protein recognition. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD25626.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AEE33107.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes At1g54470 and At1g54475.; Evidence={ECO:0000305};
CC Sequence=ANM58320.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes At1g54470 and At1g54475.; Evidence={ECO:0000305};
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DR EMBL; AC005287; AAD25626.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE33107.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; ANM58320.1; ALT_SEQ; Genomic_DNA.
DR PIR; F96586; F96586.
DR RefSeq; NP_001320765.1; NM_001333651.1.
DR RefSeq; NP_175849.2; NM_104325.3.
DR AlphaFoldDB; Q9SLI6; -.
DR SMR; Q9SLI6; -.
DR STRING; 3702.AT1G54470.2; -.
DR PRIDE; Q9SLI6; -.
DR GeneID; 28717354; -.
DR GeneID; 841889; -.
DR KEGG; ath:AT1G54470; -.
DR KEGG; ath:AT1G54475; -.
DR Araport; AT1G54470; -.
DR eggNOG; KOG0619; Eukaryota.
DR OrthoDB; 172467at2759; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SLI6; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.80.10.10; -; 4.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR SMART; SM00369; LRR_TYP; 8.
DR PROSITE; PS51450; LRR; 16.
PE 5: Uncertain;
KW Cell membrane; Glycoprotein; Leucine-rich repeat; Membrane; Receptor;
KW Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..1009
FT /note="Putative receptor-like protein 8"
FT /id="PRO_5004332646"
FT TOPO_DOM 23..961
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 962..982
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 983..1009
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REPEAT 204..231
FT /note="LRR 1; degenerate"
FT /evidence="ECO:0000305"
FT REPEAT 232..255
FT /note="LRR 2"
FT /evidence="ECO:0000255"
FT REPEAT 257..281
FT /note="LRR 3"
FT /evidence="ECO:0000255"
FT REPEAT 282..305
FT /note="LRR 4"
FT /evidence="ECO:0000255"
FT REPEAT 306..329
FT /note="LRR 5"
FT /evidence="ECO:0000255"
FT REPEAT 331..354
FT /note="LRR 6"
FT /evidence="ECO:0000255"
FT REPEAT 355..377
FT /note="LRR 7"
FT /evidence="ECO:0000255"
FT REPEAT 379..402
FT /note="LRR 8"
FT /evidence="ECO:0000255"
FT REPEAT 404..427
FT /note="LRR 9"
FT /evidence="ECO:0000255"
FT REPEAT 442..465
FT /note="LRR 10"
FT /evidence="ECO:0000255"
FT REPEAT 466..490
FT /note="LRR 11"
FT /evidence="ECO:0000255"
FT REPEAT 492..514
FT /note="LRR 12"
FT /evidence="ECO:0000255"
FT REPEAT 515..538
FT /note="LRR 13"
FT /evidence="ECO:0000255"
FT REPEAT 540..565
FT /note="LRR 14"
FT /evidence="ECO:0000255"
FT REPEAT 567..587
FT /note="LRR 15"
FT /evidence="ECO:0000255"
FT REPEAT 588..612
FT /note="LRR 16"
FT /evidence="ECO:0000255"
FT REPEAT 613..636
FT /note="LRR 17"
FT /evidence="ECO:0000255"
FT REPEAT 638..660
FT /note="LRR 18"
FT /evidence="ECO:0000255"
FT REPEAT 662..681
FT /note="LRR 19"
FT /evidence="ECO:0000255"
FT REPEAT 682..705
FT /note="LRR 20"
FT /evidence="ECO:0000255"
FT REPEAT 707..728
FT /note="LRR 21"
FT /evidence="ECO:0000255"
FT REPEAT 729..752
FT /note="LRR 22"
FT /evidence="ECO:0000255"
FT REPEAT 819..842
FT /note="LRR 23"
FT /evidence="ECO:0000255"
FT REPEAT 843..866
FT /note="LRR 24"
FT /evidence="ECO:0000255"
FT REPEAT 867..891
FT /note="LRR 25"
FT /evidence="ECO:0000255"
FT REPEAT 893..916
FT /note="LRR 26"
FT /evidence="ECO:0000255"
FT REGION 934..955
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 159
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 197
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 267
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 390
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 402
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 497
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 516
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 526
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 551
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 588
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 611
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 716
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 751
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 850
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 890
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 903
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 934
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 1009 AA; 112780 MW; 41F2707BA7A0C0D8 CRC64;
MKTNFVILLL LLCVFAISPS QQEEINQHNP GIYHQKLLYK VQQWRTSLKE SNSVELKLSL
AAIVAGVLYF LAALISSACG IGSGGLFIPI TTLVSRLDLK TGKRFLGQYL IWVILLLGQL
HECKSCIEKE RVALLDFKKY WMSITQESDL DYVFPTWNND TKSDCCQWES IMCNPTSGRL
IRLHVGASNL KENSLLNISL LHPFEEVRSL ELSAGLNGFV DNVEGYKSLR KLKNLEILDL
SYNNRFNNNI LPFINAATSL TSLSLQNNSM EGPFPFEEIK DLTNLKLLDL SRNILKGPMQ
GLTHLKKLKA LDLSNNVFSS IMELQVVCEM KNLWELDLRE NKFVGQLPLC LGRLNKLRVL
DLSSNQLNGN LPSTFNRLES LEYLSLLDNN FTGFFSFDPL ANLTKLKVFK LSSTSDMLQI
KTESEPKYQF QLSVVVIRVC SLEKIPSFLL QDNLFTIFQM PATIVHELQF LDFSVNDISG
LLPDNIGYAL PNLLRMNGSR NGFQGHLPSS MGEMVNITSL DLSYNNFSGK LPRRFVTGCF
SLKHLKLSHN NFSGHFLPRE TSFTSLEELR VDSNSFTGKI GVGLLSSNTT LSVLDMSNNF
LTGDIPSWMS NLSGLTILSI SNNFLEGTIP PSLLAIGFLS LIDLSGNLLS GSLPSRVGGE
FGIKLFLHDN MLTGPIPDTL LEKVQILDLR YNQLSGSIPQ FVNTESIYIL LMKGNNLTGS
MSRQLCDLRN IRLLDLSDNK LNGFIPSCLY NLSFGPEDTN SYVGTAITKI TPFKFYESTF
VVEDFVVISS SFQEIEIKFS MKRRYDSYFG ATEFNNDVLD YMYGMDLSSN ELSGVIPAEL
GSLSKLRVMN LSCNFLSSSI PSSFSNLKDI ESLDLSHNML QGSIPQQLTN LSSLVVFDVS
YNNLSGIIPQ GRQFNTFDEK SYLGNPLLCG PPTNRSCDAK KTSDESENGG EEEDDEAPVD
MLAFYFSSAS TYVTTLIGIF ILMCFDCPLR RAWLRIVDAS IASVKSMLP
