ID   RLPA_NOSS1              Reviewed;         371 AA.
AC   Q8YSZ4;
DT   05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   05-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Probable endolytic peptidoglycan transglycosylase RlpA {ECO:0000255|HAMAP-Rule:MF_02071};
DE            EC=4.2.2.- {ECO:0000255|HAMAP-Rule:MF_02071};
DE   Flags: Precursor;
GN   Name=rlpA {ECO:0000255|HAMAP-Rule:MF_02071}; OrderedLocusNames=alr2935;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: Lytic transglycosylase with a strong preference for naked
CC       glycan strands that lack stem peptides. {ECO:0000255|HAMAP-
CC       Rule:MF_02071}.
CC   -!- SIMILARITY: Belongs to the RlpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_02071}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000019; BAB74634.1; -; Genomic_DNA.
DR   PIR; AH2172; AH2172.
DR   RefSeq; WP_010997086.1; NZ_RSCN01000003.1.
DR   AlphaFoldDB; Q8YSZ4; -.
DR   SMR; Q8YSZ4; -.
DR   STRING; 103690.17132029; -.
DR   PRIDE; Q8YSZ4; -.
DR   EnsemblBacteria; BAB74634; BAB74634; BAB74634.
DR   KEGG; ana:alr2935; -.
DR   eggNOG; COG0797; Bacteria.
DR   OMA; MNQRHLW; -.
DR   OrthoDB; 2027419at2; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008932; F:lytic endotransglycosylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0000270; P:peptidoglycan metabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.40.10; -; 1.
DR   HAMAP; MF_02071; RlpA; 1.
DR   InterPro; IPR034718; RlpA.
DR   InterPro; IPR009009; RlpA-like_DPBB.
DR   InterPro; IPR036908; RlpA-like_sf.
DR   InterPro; IPR012997; RplA.
DR   Pfam; PF03330; DPBB_1; 1.
DR   SUPFAM; SSF50685; SSF50685; 1.
DR   TIGRFAMs; TIGR00413; rlpA; 1.
PE   3: Inferred from homology;
KW   Cell wall biogenesis/degradation; Lyase; Reference proteome; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02071"
FT   CHAIN           26..371
FT                   /note="Probable endolytic peptidoglycan transglycosylase
FT                   RlpA"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_02071"
FT                   /id="PRO_0000190004"
FT   REGION          177..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   371 AA;  39812 MW;  367B32063991B79C CRC64;
     MNQRHLWTIV ALSVTVLGTP AVGRTQTTKA TAPAQQILAS DAVKVGEFQS SEGKRTSDAV
     ITSIHPHNLG GRRAATLFIR KIPVLTFVSS NPVASVETKV GAIGDNEGVQ PYALNTEKSV
     QVASLGNLAD ARIQNRSQND DPVKRASLVA AKINQLIRDN VKADQITVSW KGADSSLVAS
     QSQNKSSSSQ QKSERYTIKV KNQELVEINQ NTRLADSTNN LANDALQATN RLRRLVGNAS
     PLKEIANLPA RSPKRSSNPI ANLPQRIASS IRLSFQGIAS FYGRGDGFAG RPTATGERFN
     PEAMTAAHRS LPFGTRVRVT NTRNGRSVVV RINDRGPFTR GRVIDLSTGA ARVLGMIGSG
     VAPVRIEVLG R