ID   RLPA_SYNY3              Reviewed;         321 AA.
AC   Q55752;
DT   05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Probable endolytic peptidoglycan transglycosylase RlpA {ECO:0000255|HAMAP-Rule:MF_02071};
DE            EC=4.2.2.- {ECO:0000255|HAMAP-Rule:MF_02071};
GN   Name=rlpA {ECO:0000255|HAMAP-Rule:MF_02071}; OrderedLocusNames=slr0423;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27184 / PCC 6803 / N-1;
RX   PubMed=8590279; DOI=10.1093/dnares/2.4.153;
RA   Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N.,
RA   Sugiura M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region
RT   from map positions 64% to 92% of the genome.";
RL   DNA Res. 2:153-166(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Lytic transglycosylase with a strong preference for naked
CC       glycan strands that lack stem peptides. {ECO:0000255|HAMAP-
CC       Rule:MF_02071}.
CC   -!- SIMILARITY: Belongs to the RlpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_02071}.
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DR   EMBL; BA000022; BAA10397.1; -; Genomic_DNA.
DR   PIR; S76551; S76551.
DR   AlphaFoldDB; Q55752; -.
DR   SMR; Q55752; -.
DR   IntAct; Q55752; 6.
DR   STRING; 1148.1001663; -.
DR   PaxDb; Q55752; -.
DR   EnsemblBacteria; BAA10397; BAA10397; BAA10397.
DR   KEGG; syn:slr0423; -.
DR   eggNOG; COG0797; Bacteria.
DR   InParanoid; Q55752; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008932; F:lytic endotransglycosylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   GO; GO:0000270; P:peptidoglycan metabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.40.10; -; 1.
DR   HAMAP; MF_02071; RlpA; 1.
DR   InterPro; IPR034718; RlpA.
DR   InterPro; IPR009009; RlpA-like_DPBB.
DR   InterPro; IPR036908; RlpA-like_sf.
DR   InterPro; IPR012997; RplA.
DR   Pfam; PF03330; DPBB_1; 1.
DR   SUPFAM; SSF50685; SSF50685; 1.
DR   TIGRFAMs; TIGR00413; rlpA; 1.
PE   3: Inferred from homology;
KW   Cell wall biogenesis/degradation; Lyase; Reference proteome.
FT   CHAIN           1..321
FT                   /note="Probable endolytic peptidoglycan transglycosylase
FT                   RlpA"
FT                   /id="PRO_0000190007"
SQ   SEQUENCE   321 AA;  33769 MW;  E1E1AAFC29772941 CRC64;
     MKGINVCRSI AGVIGTASLT TLVWGNCPSG LLALNAITQA DAPTAVSENN SSLAPLESSV
     TATSSTPAPA FQDTELISLV PHQGPENRLA VTLRVNQIPV VTFLGTATEL AALSNDQVTD
     TMERAQTVAR RLDELSGAEF FDPSTIKVGL DATTRQLVVK SEDEILLTIN KNTVLPEKKL
     SAPETALQTA NRLRRLLGGA EPIVALPAAL QVARVNTFDA AATIKRIKGG IASWYGPGFH
     GRRTANGERF NQNALTAAHR TLPFGTRVKV TNLRNGQSVV VRINDRGPFT GGRVIDLSAG
     AARAIGIHSS GVGNVALDIV Q