RLR06_PLAHL
ID RLR06_PLAHL Reviewed; 168 AA.
AC A0A0P1AXF0;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2016, sequence version 1.
DT 25-MAY-2022, entry version 20.
DE RecName: Full=Secreted RxLR effector protein RXLR-C06 {ECO:0000303|PubMed:30422341};
DE Flags: Precursor;
GN Name=RXLR-C06 {ECO:0000303|PubMed:30422341};
OS Plasmopara halstedii (Downy mildew of sunflower).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=4781;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26438312; DOI=10.1186/s12864-015-1904-7;
RA Sharma R., Xia X., Cano L.M., Evangelisti E., Kemen E., Judelson H.,
RA Oome S., Sambles C., van den Hoogen D.J., Kitner M., Klein J., Meijer H.J.,
RA Spring O., Win J., Zipper R., Bode H.B., Govers F., Kamoun S.,
RA Schornack S., Studholme D.J., Van den Ackerveken G., Thines M.;
RT "Genome analyses of the sunflower pathogen Plasmopara halstedii provide
RT insights into effector evolution in downy mildews and Phytophthora.";
RL BMC Genomics 16:741-741(2015).
RN [2]
RP DOMAIN, INDUCTION, FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=30422341; DOI=10.1111/tpj.14157;
RA Pecrix Y., Buendia L., Penouilh-Suzette C., Marechaux M., Legrand L.,
RA Bouchez O., Rengel D., Gouzy J., Cottret L., Vear F., Godiard L.;
RT "Sunflower resistance to multiple downy mildew pathotypes revealed by
RT recognition of conserved effectors of the oomycete Plasmopara halstedii.";
RL Plant J. 97:730-748(2019).
CC -!- FUNCTION: Secreted effector that suppresses pattern-triggered immunity
CC (PTI) in plant host. {ECO:0000269|PubMed:30422341}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:30422341}. Host
CC Golgi apparatus {ECO:0000269|PubMed:30422341}.
CC -!- INDUCTION: Expression is up-regulated in spores.
CC {ECO:0000269|PubMed:30422341}.
CC -!- DOMAIN: The RxLR-dEER motif acts to carry the protein into the host
CC cell cytoplasm through binding to cell surface phosphatidylinositol-3-
CC phosphate. {ECO:0000305|PubMed:30422341}.
CC -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR EMBL; CCYD01001640; CEG45744.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P1AXF0; -.
DR EnsemblProtists; CEG45744; CEG45744; CEG45744.
DR Proteomes; UP000054928; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR PROSITE; PS50096; IQ; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Host Golgi apparatus; Reference proteome; Secreted; Signal;
KW Virulence.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..168
FT /note="Secreted RxLR effector protein RXLR-C06"
FT /id="PRO_5006059009"
FT DOMAIN 78..107
FT /note="IQ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00116"
FT REGION 25..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 46..63
FT /note="RxLR-dEER"
FT /evidence="ECO:0000305|PubMed:30422341"
FT COMPBIAS 25..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 37
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 42
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 105
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 168 AA; 19129 MW; 335E67152B5C115C CRC64;
MRIQLLWLSF AVLSTILSTC DATSDKLDPQ RVQPNQNGSG HNQSIRSALK TSHGKTIADD
EERFISLSGM SEKIAKYYKA IVAKLSKYFR DYHERREIRK QRILNKSFAE MMAGQKSVED
IGRNQDASFM SSSFLWTPEA FKSILHKYAL FLYKYGNGHL ATVPVKTG
