RLR11_PLAHL
ID RLR11_PLAHL Reviewed; 160 AA.
AC A0A0P1ATM7;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2016, sequence version 1.
DT 25-MAY-2022, entry version 18.
DE RecName: Full=Secreted RxLR effector protein RXLR-C11 {ECO:0000303|PubMed:30422341};
DE Flags: Precursor;
GN Name=RXLR-C11 {ECO:0000303|PubMed:30422341};
OS Plasmopara halstedii (Downy mildew of sunflower).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=4781;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26438312; DOI=10.1186/s12864-015-1904-7;
RA Sharma R., Xia X., Cano L.M., Evangelisti E., Kemen E., Judelson H.,
RA Oome S., Sambles C., van den Hoogen D.J., Kitner M., Klein J., Meijer H.J.,
RA Spring O., Win J., Zipper R., Bode H.B., Govers F., Kamoun S.,
RA Schornack S., Studholme D.J., Van den Ackerveken G., Thines M.;
RT "Genome analyses of the sunflower pathogen Plasmopara halstedii provide
RT insights into effector evolution in downy mildews and Phytophthora.";
RL BMC Genomics 16:741-741(2015).
RN [2]
RP DOMAIN, INDUCTION, FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=30422341; DOI=10.1111/tpj.14157;
RA Pecrix Y., Buendia L., Penouilh-Suzette C., Marechaux M., Legrand L.,
RA Bouchez O., Rengel D., Gouzy J., Cottret L., Vear F., Godiard L.;
RT "Sunflower resistance to multiple downy mildew pathotypes revealed by
RT recognition of conserved effectors of the oomycete Plasmopara halstedii.";
RL Plant J. 97:730-748(2019).
CC -!- FUNCTION: Secreted effector that suppresses pattern-triggered immunity
CC (PTI) in plant host. {ECO:0000269|PubMed:30422341}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:30422341}. Host cell
CC membrane {ECO:0000269|PubMed:30422341}. Host nucleus
CC {ECO:0000269|PubMed:30422341}.
CC -!- INDUCTION: Expression is up-regulated in spores.
CC {ECO:0000269|PubMed:30422341}.
CC -!- DOMAIN: The RxLR-dEER motif acts to carry the protein into the host
CC cell cytoplasm through binding to cell surface phosphatidylinositol-3-
CC phosphate. {ECO:0000305|PubMed:30422341}.
CC -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR EMBL; CCYD01001204; CEG44407.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P1ATM7; -.
DR EnsemblProtists; CEG44407; CEG44407; CEG44407.
DR Proteomes; UP000054928; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR031825; RXLR.
DR Pfam; PF16810; RXLR; 1.
PE 2: Evidence at transcript level;
KW Host cell membrane; Host membrane; Host nucleus; Membrane;
KW Reference proteome; Secreted; Signal; Virulence.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..160
FT /note="Secreted RxLR effector protein RXLR-C11"
FT /id="PRO_5006058918"
FT MOTIF 58..75
FT /note="RxLR-dEER"
FT /evidence="ECO:0000305|PubMed:30422341"
SQ SEQUENCE 160 AA; 18187 MW; 6CDE4D11EB457528 CRC64;
MHFSLVLLVF AAIVIPICAD TSTTKDYDDK KSLQTSNFGT AAVANMLHVL QSSDNSKRLL
RMNDKAVISD HEEERSSLVK NKQKKLSYRI KKGWENVKKP FKKSAKIIEK PLKKGSKIII
EPFKKVSKII KKFAIKGAKI VKKPFKKSAR IIKKSFKNLN