RLR13_PLAHL
ID RLR13_PLAHL Reviewed; 125 AA.
AC A0A0P1AM89;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2016, sequence version 1.
DT 25-MAY-2022, entry version 18.
DE RecName: Full=Secreted RxLR effector protein RXLR-C13 {ECO:0000303|PubMed:30422341};
DE Flags: Precursor;
GN Name=RXLR-C131 {ECO:0000303|PubMed:30422341};
OS Plasmopara halstedii (Downy mildew of sunflower).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=4781;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=26438312; DOI=10.1186/s12864-015-1904-7;
RA Sharma R., Xia X., Cano L.M., Evangelisti E., Kemen E., Judelson H.,
RA Oome S., Sambles C., van den Hoogen D.J., Kitner M., Klein J., Meijer H.J.,
RA Spring O., Win J., Zipper R., Bode H.B., Govers F., Kamoun S.,
RA Schornack S., Studholme D.J., Van den Ackerveken G., Thines M.;
RT "Genome analyses of the sunflower pathogen Plasmopara halstedii provide
RT insights into effector evolution in downy mildews and Phytophthora.";
RL BMC Genomics 16:741-741(2015).
RN [2]
RP DOMAIN, INDUCTION, FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=30422341; DOI=10.1111/tpj.14157;
RA Pecrix Y., Buendia L., Penouilh-Suzette C., Marechaux M., Legrand L.,
RA Bouchez O., Rengel D., Gouzy J., Cottret L., Vear F., Godiard L.;
RT "Sunflower resistance to multiple downy mildew pathotypes revealed by
RT recognition of conserved effectors of the oomycete Plasmopara halstedii.";
RL Plant J. 97:730-748(2019).
CC -!- FUNCTION: Secreted effector that does not suppress pattern-triggered
CC immunity (PTI) in plant host. {ECO:0000269|PubMed:30422341}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:30422341}. Host
CC endoplasmic reticulum membrane {ECO:0000269|PubMed:30422341}; Single-
CC pass membrane protein {ECO:0000255}.
CC -!- INDUCTION: Expression is up-regulated during the early plant infection
CC stages. {ECO:0000269|PubMed:30422341}.
CC -!- DOMAIN: Has the canonical translocation RxLR motif, but lacks the
CC canonical EER motif, which characterizes most oomycete effectors
CC identified so far. {ECO:0000305|PubMed:30422341}.
CC -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR EMBL; CCYD01000610; CEG42169.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0P1AM89; -.
DR SMR; A0A0P1AM89; -.
DR EnsemblProtists; CEG42169; CEG42169; CEG42169.
DR OrthoDB; 1492852at2759; -.
DR Proteomes; UP000054928; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW Glycoprotein; Host endoplasmic reticulum; Host membrane; Membrane;
KW Reference proteome; Secreted; Signal; Transmembrane; Transmembrane helix;
KW Virulence.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..125
FT /note="Secreted RxLR effector protein RXLR-C13"
FT /id="PRO_5006058771"
FT TRANSMEM 106..123
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOTIF 43..73
FT /note="RxLR-dEER"
FT /evidence="ECO:0000305|PubMed:30422341"
FT CARBOHYD 85
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 125 AA; 13911 MW; AB130AED39C9A945 CRC64;
MVNSLTFTLV VVCLVRSCDG VAAVSSDMID STNNRISRNM IRRVLQETAT ANDDVKKLST
STKVDSKLNQ EIKTKPDQLV KAEKNSSKIG AWLKRMNVIS SKRDKFFILA TILLFPIAAY
MVASR
