RLR15_PLAVT
ID RLR15_PLAVT Reviewed; 136 AA.
AC P0CU98;
DT 18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT 18-SEP-2019, sequence version 1.
DT 25-MAY-2022, entry version 8.
DE RecName: Full=Secreted RxLR effector protein 15 {ECO:0000303|PubMed:29706971};
DE Flags: Precursor;
GN Name=RXLR15 {ECO:0000303|PubMed:29706971};
OS Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=143451;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], DOMAIN, FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=29706971; DOI=10.3389/fpls.2018.00286;
RA Liu Y., Lan X., Song S., Yin L., Dry I.B., Qu J., Xiang J., Lu J.;
RT "In planta functional analysis and subcellular localization of the oomycete
RT pathogen Plasmopara viticola candidate RXLR effector repertoire.";
RL Front. Plant Sci. 9:286-286(2018).
CC -!- FUNCTION: Effector that completely suppresses the host cell death
CC induced by cell death-inducing proteins. {ECO:0000269|PubMed:29706971}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29706971}. Host
CC nucleus {ECO:0000269|PubMed:29706971}. Host cytoplasm
CC {ECO:0000269|PubMed:29706971}.
CC -!- DOMAIN: Has the canonical translocation RxLR motif, but lacks the
CC canonical EER motif, which characterizes most oomycete effectors
CC identified so far. {ECO:0000305|PubMed:29706971}.
CC -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR AlphaFoldDB; P0CU98; -.
DR SMR; P0CU98; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR031825; RXLR.
DR Pfam; PF16810; RXLR; 1.
PE 2: Evidence at transcript level;
KW Host cytoplasm; Host nucleus; Secreted; Signal; Virulence.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..136
FT /note="Secreted RxLR effector protein 15"
FT /id="PRO_0000447907"
FT MOTIF 47..50
FT /note="RxLR"
FT /evidence="ECO:0000305|PubMed:29706971"
SQ SEQUENCE 136 AA; 15476 MW; 46AF3A4CB02066BD CRC64;
MRGHSALMMA VVTLAAVSSG AAEVANTAAV SSDYLIGTIL TFAESDRLLR VNDVDDVPVY
HYPPEKGKRT TFFEDRMKKK LANPEKIRRL YWKWYSMGYS AREVVQHLDQ TDNRELKEIY
HNLGVGYAEF VAKMNV