RLR1_PLAVT
ID RLR1_PLAVT Reviewed; 134 AA.
AC A0A172M419;
DT 08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT 07-SEP-2016, sequence version 1.
DT 25-MAY-2022, entry version 13.
DE RecName: Full=Secreted RxLR effector protein 1 {ECO:0000303|Ref.2};
DE Flags: Precursor;
GN Name=RxLR1 {ECO:0000303|Ref.2};
OS Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=143451;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], INDUCTION, FUNCTION, AND SUBCELLULAR LOCATION.
RC STRAIN=ZJ-1-1;
RX PubMed=27242731; DOI=10.3389/fmicb.2016.00709;
RA Xiang J., Li X., Wu J., Yin L., Zhang Y., Lu J.;
RT "Studying the mechanism of Plasmopara viticola RxLR effectors on
RT suppressing plant immunity.";
RL Front. Microbiol. 7:709-709(2016).
RN [2]
RP IDENTIFICATION, INDUCTION, FUNCTION, AND DOMAIN.
RX DOI=10.1016/j.pmpp.2015.05.002;
RA Yin L., Li X., Xiang J., Qu J., Zhang Y., Dry I.B., Lu J.;
RT "Characterization of the secretome of Plasmopara viticola by de novo
RT transcriptome analysis.";
RL Physiol. Mol. Plant Pathol. 91:1-10(2015).
CC -!- FUNCTION: Effector that acts as a broad suppressor of cell death to
CC interrupt plant immunity. Inhibits cell death induced by cell death-
CC inducing proteins, including the PAMP elicitor INF1 from P.infestans.
CC {ECO:0000269|PubMed:27242731, ECO:0000269|Ref.2}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:27242731}. Host
CC nucleus {ECO:0000269|PubMed:27242731}.
CC -!- INDUCTION: Expression is up-regulated at the earlier infection stages.
CC {ECO:0000269|PubMed:27242731, ECO:0000269|Ref.2}.
CC -!- DOMAIN: The RxLR-dEER motif acts to carry the protein into the host
CC cell cytoplasm through binding to cell surface phosphatidylinositol-3-
CC phosphate. {ECO:0000305|Ref.2}.
CC -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR EMBL; KX010946; ANC73366.1; -; mRNA.
DR AlphaFoldDB; A0A172M419; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
PE 2: Evidence at transcript level;
KW Host nucleus; Secreted; Signal; Virulence.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..134
FT /note="Secreted RxLR effector protein 1"
FT /id="PRO_5007999416"
FT REGION 32..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 57..79
FT /note="RxLR-dEER"
FT /evidence="ECO:0000305|Ref.2"
FT COMPBIAS 32..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 134 AA; 14981 MW; 736494214897A9A8 CRC64;
MFCRSPLVAV ILLVLATHIV LALGDATRIA ASETVPSDSS QTTRKSTRRT TSVDNKRRLR
QQIMGKDGPV VNDVHAEERG FLNNKLAYKM FGDGLDMQEK IIKSGGKGLK NVLRKRLYNK
VSRAEHRQVP ATRH