ID   RLR36_PLAVT             Reviewed;         399 AA.
AC   P0CV05;
DT   18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2019, sequence version 1.
DT   25-MAY-2022, entry version 9.
DE   RecName: Full=Secreted RxLR effector protein 36 {ECO:0000303|PubMed:29706971};
DE   Flags: Precursor;
GN   Name=RXLR36 {ECO:0000303|PubMed:29706971};
OS   Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Plasmopara.
OX   NCBI_TaxID=143451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DOMAIN, FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=29706971; DOI=10.3389/fpls.2018.00286;
RA   Liu Y., Lan X., Song S., Yin L., Dry I.B., Qu J., Xiang J., Lu J.;
RT   "In planta functional analysis and subcellular localization of the oomycete
RT   pathogen Plasmopara viticola candidate RXLR effector repertoire.";
RL   Front. Plant Sci. 9:286-286(2018).
CC   -!- FUNCTION: Secreted effector that completely suppresses the host cell
CC       death induced by cell death-inducing proteins.
CC       {ECO:0000269|PubMed:29706971}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29706971}. Host
CC       nucleus {ECO:0000269|PubMed:29706971}.
CC   -!- DOMAIN: The RxLR-dEER motif acts to carry the protein into the host
CC       cell cytoplasm through binding to cell surface phosphatidylinositol-3-
CC       phosphate. {ECO:0000305|PubMed:29706971}.
CC   -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR   AlphaFoldDB; P0CV05; -.
DR   SMR; P0CV05; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Host nucleus; Secreted; Signal; Virulence.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..399
FT                   /note="Secreted RxLR effector protein 36"
FT                   /id="PRO_0000447914"
FT   REGION          126..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           50..71
FT                   /note="RxLR-dEER"
FT                   /evidence="ECO:0000305|PubMed:29706971"
FT   CARBOHYD        75
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ   SEQUENCE   399 AA;  44095 MW;  87A2B55BCBEDB6A5 CRC64;
     MRGTIYVAIA ILVAASSRSS AESDQVEPQQ APNSDFVTSD DTIYEVLPTR ILRESRGSND
     KLAVGAGDEE RMMNNLSNGN SLSESLEQTT IKLTTDDVIA KAEEAIKNFK QLEPVLNMIR
     RKRQRIDPTP SNLGGQALHA PPNPDKSLVS VTENAPNVIA NRLEKSGPTV IMKNAVRSIT
     QHDYRPAPSG SSTTSAAATD IRLHEQPIAR KGSELFKNIY PNKMVSNSVE HPLHMLEGNE
     NSAHTVTVNG ITYLMAQGPA LGRKDTVNEE AKKIHEAFLK AFSLPFHQYP EETTHMLRLL
     RWSYNSSPNN INTATSLKDL ANSQDPDVIM NLLDMDLKKL LGDGRSAVKA TEKNLKEAYS
     VKLLIMYELF YDFCHGNRKL VGNLPSKSDR VDSILKVTT