ID   RLR55_PLAVT             Reviewed;         125 AA.
AC   A0A182BSS3;
DT   08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT   07-SEP-2016, sequence version 1.
DT   25-MAY-2022, entry version 12.
DE   RecName: Full=Secreted RxLR effector protein 55 {ECO:0000303|PubMed:27242731};
DE   Flags: Precursor;
GN   Name=RxLR55 {ECO:0000303|PubMed:27242731};
OS   Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Plasmopara.
OX   NCBI_TaxID=143451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], INDUCTION, FUNCTION, SUBCELLULAR LOCATION, AND
RP   DOMAIN.
RC   STRAIN=ZJ-1-1;
RX   PubMed=27242731; DOI=10.3389/fmicb.2016.00709;
RA   Xiang J., Li X., Wu J., Yin L., Zhang Y., Lu J.;
RT   "Studying the mechanism of Plasmopara viticola RxLR effectors on
RT   suppressing plant immunity.";
RL   Front. Microbiol. 7:709-709(2016).
CC   -!- FUNCTION: Effector that acts as a broad suppressor of cell death to
CC       interrupt plant immunity. Inhibits cell death induced by cell death-
CC       inducing proteins, including the PAMP elicitor INF1 from P.infestans.
CC       {ECO:0000269|PubMed:27242731}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:27242731}. Host cell
CC       membrane {ECO:0000269|PubMed:27242731}; Single-pass membrane protein
CC       {ECO:0000255}.
CC   -!- INDUCTION: Expression is up-regulated at later stages of infection.
CC       {ECO:0000269|PubMed:27242731}.
CC   -!- DOMAIN: Has a conserved RxLR motif that acts to carry the protein into
CC       the host cell cytoplasm. Lacks the 'so-called' EER motif, which is
CC       found closely behind the RxLR motif in most of RxLR effector family
CC       members, but the presence of an EER motif is not always essential for
CC       the translocation of every RxLR effector into host cells, or for
CC       inducing a hypersensitive response. {ECO:0000305|PubMed:27242731}.
CC   -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR   EMBL; KX010962; ANC73382.1; -; mRNA.
DR   AlphaFoldDB; A0A182BSS3; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Host cell membrane; Host membrane; Membrane; Secreted;
KW   Signal; Transmembrane; Transmembrane helix; Virulence.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..125
FT                   /note="Secreted RxLR effector protein 55"
FT                   /id="PRO_5008116088"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          51..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           35..38
FT                   /note="RxLR"
FT                   /evidence="ECO:0000305|PubMed:27242731"
FT   COMPBIAS        51..83
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        74
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ   SEQUENCE   125 AA;  12700 MW;  23784A26F21C9DEA CRC64;
     MAASRSSITT LLLLIVAVAL GYGILPISAK TSVARQLREQ VDFVDAAALS ESATSSSSSS
     ALDHKSSAPG EATNASETEH SAASTASEPK HEGPTMMSFV GPAAAGVLAI LLIGAVIAFK
     KRMNK