RLR73_PLAVT
ID RLR73_PLAVT Reviewed; 402 AA.
AC P0CV23;
DT 18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT 18-SEP-2019, sequence version 1.
DT 25-MAY-2022, entry version 9.
DE RecName: Full=Secreted RxLR effector protein 73 {ECO:0000303|PubMed:29706971};
DE Flags: Precursor;
GN Name=RXLR73 {ECO:0000303|PubMed:29706971};
OS Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Plasmopara.
OX NCBI_TaxID=143451;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], DOMAIN, FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=29706971; DOI=10.3389/fpls.2018.00286;
RA Liu Y., Lan X., Song S., Yin L., Dry I.B., Qu J., Xiang J., Lu J.;
RT "In planta functional analysis and subcellular localization of the oomycete
RT pathogen Plasmopara viticola candidate RXLR effector repertoire.";
RL Front. Plant Sci. 9:286-286(2018).
CC -!- FUNCTION: Secreted effector that completely suppresses the host cell
CC death induced by cell death-inducing proteins.
CC {ECO:0000269|PubMed:29706971}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29706971}. Host cell
CC {ECO:0000305|PubMed:29706971}.
CC -!- DOMAIN: Has the canonical translocation RxLR motif, but lacks the
CC canonical EER motif, which characterizes most oomycete effectors
CC identified so far. {ECO:0000305|PubMed:29706971}.
CC -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR AlphaFoldDB; P0CV23; -.
DR SMR; P0CV23; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0043657; C:host cell; IEA:UniProtKB-SubCell.
DR Gene3D; 2.40.10.10; -; 2.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR SUPFAM; SSF50494; SSF50494; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Secreted; Signal; Virulence.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..402
FT /note="Secreted RxLR effector protein 73"
FT /id="PRO_0000447932"
FT MOTIF 104..107
FT /note="RxLR"
FT /evidence="ECO:0000305|PubMed:29706971"
FT CARBOHYD 27
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 111
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 134
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 143
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 165
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 286
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 402 AA; 43062 MW; CB1FAC575BCE7D6F CRC64;
MRLLHVVVAT VSLTGAITSL IAAQHYNVSS DVIGGIEKED FGVGCNSRTK YPTAADTSKL
QPRFAYLITN SLADFIAVHF IKFNLPDNDF VQIRAADPSA VDNRVLRYRG NESNGVFFAD
ALSTKSVIVE LFTNASSSAQ KTNSSKCVGF AVDSYQYLGE GSTLNGSKEE VCGADNSREA
SCYSGYTNAF RASNAVVRLL IKKSTGSFFC TGWLIGSEGH LITNNHCIST QSHASNTEFE
FMAQGSSCSI NCEGARACFG SIRASYATLI YADATLDYAL VKLPINLSGQ YGYLRLRSSG
AVMNERVYVP QHPAGWGKRI AMKSDNGFGT VTSLTMGGCA PNQVAYYLDT QGGSSGSPVL
SWSDNAVVAL HHCGGCPNTA INSYKLVNDM KWRGILPANA CT