ID   RLR85_PLAVT             Reviewed;         276 AA.
AC   P0CV30;
DT   18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2019, sequence version 1.
DT   25-MAY-2022, entry version 9.
DE   RecName: Full=Secreted RxLR effector protein 85 {ECO:0000303|PubMed:29706971};
DE   Flags: Precursor;
GN   Name=RXLR85 {ECO:0000303|PubMed:29706971};
OS   Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Plasmopara.
OX   NCBI_TaxID=143451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DOMAIN, FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=29706971; DOI=10.3389/fpls.2018.00286;
RA   Liu Y., Lan X., Song S., Yin L., Dry I.B., Qu J., Xiang J., Lu J.;
RT   "In planta functional analysis and subcellular localization of the oomycete
RT   pathogen Plasmopara viticola candidate RXLR effector repertoire.";
RL   Front. Plant Sci. 9:286-286(2018).
CC   -!- FUNCTION: Secreted effector that partially suppresses the host cell
CC       death induced by cell death-inducing proteins.
CC       {ECO:0000269|PubMed:29706971}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29706971}. Host cell
CC       membrane {ECO:0000269|PubMed:29706971}.
CC   -!- DOMAIN: Has the canonical translocation RxLR motif, but lacks the
CC       canonical EER motif, which characterizes most oomycete effectors
CC       identified so far. {ECO:0000305|PubMed:29706971}.
CC   -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR   AlphaFoldDB; P0CV30; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Host cell membrane; Host membrane; Membrane; Secreted; Signal; Virulence.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..276
FT                   /note="Secreted RxLR effector protein 85"
FT                   /id="PRO_0000447939"
FT   MOTIF           110..113
FT                   /note="RxLR"
FT                   /evidence="ECO:0000305|PubMed:29706971"
SQ   SEQUENCE   276 AA;  31478 MW;  D3AACDC4A8E49EF2 CRC64;
     MRYCAFRLGL FFIGYSCCVL LSTPTLASSL EKSDAESTQT EQWNSNGKRI LEADDPKLSL
     EGERGITPEV VPAFEAIGKA KTPEKAVPRM SLRSKLNPVN WAKGLWFKLR QLRARYRAWR
     LRRIIADKRG LGPALLNGLT PLHVKNVKDE TIRYSKFGPD AINQIEKDYD SFVKLYFAQF
     DGLHKDPPIV KMDILDKMVK EMSSIERLAV RTSLDRVRLT VDAGYSFEKL ISLDVSPLLY
     MRLLDAEGAF SDVDKNRDAI NHLKGYVKAY YKHITL