RM09_MOUSE
ID RM09_MOUSE Reviewed; 265 AA.
AC Q99N94; Q3TSJ0; Q8BQZ2;
DT 13-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=39S ribosomal protein L9, mitochondrial;
DE Short=L9mt;
DE Short=MRP-L9;
DE Flags: Precursor;
GN Name=Mrpl9;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Corpora quadrigemina, and Muellerian duct;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 10-265.
RX PubMed=11279069; DOI=10.1074/jbc.m100432200;
RA Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A.,
RA Watanabe K.;
RT "Structural compensation for the deficit of rRNA with proteins in the
RT mammalian mitochondrial ribosome. Systematic analysis of protein components
RT of the large ribosomal subunit from mammalian mitochondria.";
RL J. Biol. Chem. 276:21724-21736(2001).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, and Spleen;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC which comprises a 16S rRNA and about 50 distinct proteins.
CC {ECO:0000250|UniProtKB:Q9BYD2}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9BYD2}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL9 family.
CC {ECO:0000305}.
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DR EMBL; AK046099; BAC32604.1; -; mRNA.
DR EMBL; AK162023; BAE36685.1; -; mRNA.
DR EMBL; AB049637; BAB40842.1; -; mRNA.
DR CCDS; CCDS17593.1; -.
DR RefSeq; NP_084392.1; NM_030116.2.
DR AlphaFoldDB; Q99N94; -.
DR SMR; Q99N94; -.
DR BioGRID; 219457; 21.
DR ComplexPortal; CPX-5302; 39S mitochondrial large ribosomal subunit.
DR STRING; 10090.ENSMUSP00000029786; -.
DR iPTMnet; Q99N94; -.
DR PhosphoSitePlus; Q99N94; -.
DR EPD; Q99N94; -.
DR MaxQB; Q99N94; -.
DR PaxDb; Q99N94; -.
DR PRIDE; Q99N94; -.
DR ProteomicsDB; 301600; -.
DR Antibodypedia; 1667; 193 antibodies from 26 providers.
DR DNASU; 78523; -.
DR Ensembl; ENSMUST00000029786; ENSMUSP00000029786; ENSMUSG00000028140.
DR GeneID; 78523; -.
DR KEGG; mmu:78523; -.
DR UCSC; uc008qgi.1; mouse.
DR CTD; 65005; -.
DR MGI; MGI:2137211; Mrpl9.
DR VEuPathDB; HostDB:ENSMUSG00000028140; -.
DR eggNOG; KOG4607; Eukaryota.
DR GeneTree; ENSGT00390000008281; -.
DR HOGENOM; CLU_078938_0_0_1; -.
DR InParanoid; Q99N94; -.
DR OMA; KAGFHCK; -.
DR OrthoDB; 1036760at2759; -.
DR PhylomeDB; Q99N94; -.
DR TreeFam; TF300170; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 78523; 13 hits in 74 CRISPR screens.
DR ChiTaRS; Mrpl9; mouse.
DR PRO; PR:Q99N94; -.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; Q99N94; protein.
DR Bgee; ENSMUSG00000028140; Expressed in urinary bladder urothelium and 255 other tissues.
DR ExpressionAtlas; Q99N94; baseline and differential.
DR Genevisible; Q99N94; MM.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0032543; P:mitochondrial translation; IC:ComplexPortal.
DR Gene3D; 3.40.5.10; -; 1.
DR InterPro; IPR000244; Ribosomal_L9.
DR InterPro; IPR009027; Ribosomal_L9/RNase_H1_N.
DR InterPro; IPR020070; Ribosomal_L9_N.
DR InterPro; IPR036935; Ribosomal_L9_N_sf.
DR PANTHER; PTHR21368; PTHR21368; 1.
DR Pfam; PF01281; Ribosomal_L9_N; 1.
DR SUPFAM; SSF55658; SSF55658; 1.
PE 1: Evidence at protein level;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW Transit peptide.
FT TRANSIT 1..49
FT /note="Mitochondrion"
FT /evidence="ECO:0000250|UniProtKB:Q2TBK2"
FT CHAIN 50..265
FT /note="39S ribosomal protein L9, mitochondrial"
FT /id="PRO_0000030551"
SQ SEQUENCE 265 AA; 30244 MW; 9A14116C1834AE56 CRC64;
MAASVAPGVR TLWWAGAAWL RQGGIRELFR PRIEGSTPGR DFSLSHYQST VIVERWWKVP
LAGEGRKPHL HRRHRVYKLV EDTKHRPKDN LELILTQSVD EIGVRGDLVS VKKSVGRNKL
LSQGLAVYAS PENRKLFEEE KSLRREGKLE KIQTKAGEAT VKFLRSCHLE VGMKNNVKWE
LNPEIVARHF FKNLGVVVAP HALRLPEEPI TRWGEYWCDV TVNGLDTVRV PMSVVLFQKP
KTKRYKHWLA QQAAKSVAPT NPQAV
