ID   RM19_DROME              Reviewed;         306 AA.
AC   Q9VHN6;
DT   26-JUL-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 145.
DE   RecName: Full=39S ribosomal protein L19, mitochondrial;
DE            Short=L19mt;
DE            Short=MRP-L19;
DE   Flags: Precursor;
GN   Name=mRpL19; ORFNames=CG8039;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins.
CC       {ECO:0000250|UniProtKB:P49406}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:P49406}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL19 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE014297; AAF54266.1; -; Genomic_DNA.
DR   EMBL; AY061413; AAL28961.1; -; mRNA.
DR   RefSeq; NP_524284.1; NM_079560.5.
DR   AlphaFoldDB; Q9VHN6; -.
DR   SMR; Q9VHN6; -.
DR   BioGRID; 66203; 1.
DR   DIP; DIP-23691N; -.
DR   STRING; 7227.FBpp0081384; -.
DR   PaxDb; Q9VHN6; -.
DR   PRIDE; Q9VHN6; -.
DR   DNASU; 41028; -.
DR   EnsemblMetazoa; FBtr0081901; FBpp0081384; FBgn0037608.
DR   GeneID; 41028; -.
DR   KEGG; dme:Dmel_CG8039; -.
DR   CTD; 9801; -.
DR   FlyBase; FBgn0037608; mRpL19.
DR   VEuPathDB; VectorBase:FBgn0037608; -.
DR   eggNOG; KOG1698; Eukaryota.
DR   GeneTree; ENSGT00390000009415; -.
DR   HOGENOM; CLU_076988_0_0_1; -.
DR   InParanoid; Q9VHN6; -.
DR   OMA; IDHQGME; -.
DR   OrthoDB; 1387536at2759; -.
DR   PhylomeDB; Q9VHN6; -.
DR   Reactome; R-DME-5389840; Mitochondrial translation elongation.
DR   Reactome; R-DME-5419276; Mitochondrial translation termination.
DR   BioGRID-ORCS; 41028; 0 hits in 1 CRISPR screen.
DR   GenomeRNAi; 41028; -.
DR   PRO; PR:Q9VHN6; -.
DR   Proteomes; UP000000803; Chromosome 3R.
DR   Bgee; FBgn0037608; Expressed in eye disc (Drosophila) and 40 other tissues.
DR   Genevisible; Q9VHN6; DM.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:FlyBase.
DR   GO; GO:0032543; P:mitochondrial translation; TAS:FlyBase.
DR   Gene3D; 2.30.30.790; -; 1.
DR   InterPro; IPR038657; L19_sf.
DR   InterPro; IPR001857; Ribosomal_L19.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR15680; PTHR15680; 1.
DR   Pfam; PF01245; Ribosomal_L19; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..306
FT                   /note="39S ribosomal protein L19, mitochondrial"
FT                   /id="PRO_0000030475"
FT   REGION          34..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   306 AA;  36193 MW;  1A575360C6E7744E CRC64;
     MNLSTRVMLN RLTQQCVYKR IVTFSTKTAE HVIENQEEQK KEAPPTTPTS PVNRKTIIPA
     NYRFVYPEFL PDPKVEWRNL VREKLERLDM LDRRKQIDLP EFYVGSVLAV TSSDPHAAGK
     TSRFVGICIN RDRCGLRARF ILRNVIDHQG MEVVYELYDP TILKIEVLRL EKRLDDSLFY
     LRDALPEYST FDENMEAEPL EEGAPVPVND IKVVLRPRPW LERWERQNLR GVANIDEYLK
     DKHRLSAAKV QKPWEKYDMM KDYRSSIPEE EQTEIFAEVH TELHALELQR KRNKRKRTFI
     KPKQLA