RM25_SCHPO
ID RM25_SCHPO Reviewed; 145 AA.
AC Q9UUJ5;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 18-APR-2012, sequence version 2.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=54S ribosomal protein L25, mitochondrial;
DE Flags: Precursor;
GN Name=mrpl25; ORFNames=SPAC1952.14c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP REVISION OF GENE MODEL.
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBUNIT: Component of the mitochondrial large ribosomal subunit. Mature
CC mitochondrial ribosomes consist of a small (37S) and a large (54S)
CC subunit. The 37S subunit contains at least 33 different proteins and 1
CC molecule of RNA (15S). The 54S subunit contains at least 45 different
CC proteins and 1 molecule of RNA (21S).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mL59 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB52578.2; -; Genomic_DNA.
DR PIR; T37942; T37942.
DR RefSeq; NP_594816.2; NM_001020245.2.
DR AlphaFoldDB; Q9UUJ5; -.
DR SMR; Q9UUJ5; -.
DR MaxQB; Q9UUJ5; -.
DR PaxDb; Q9UUJ5; -.
DR EnsemblFungi; SPAC1952.14c.1; SPAC1952.14c.1:pep; SPAC1952.14c.
DR GeneID; 2542604; -.
DR KEGG; spo:SPAC1952.14c; -.
DR PomBase; SPAC1952.14c; mrpl25.
DR VEuPathDB; FungiDB:SPAC1952.14c; -.
DR HOGENOM; CLU_076154_2_0_1; -.
DR InParanoid; Q9UUJ5; -.
DR OMA; VISKEVW; -.
DR PRO; PR:Q9UUJ5; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:PomBase.
DR GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR GO; GO:0003735; F:structural constituent of ribosome; ISS:PomBase.
DR GO; GO:0032543; P:mitochondrial translation; ISS:PomBase.
DR InterPro; IPR037507; MrpL25.
DR InterPro; IPR040922; MRPL25_dom.
DR PANTHER; PTHR28041; PTHR28041; 1.
DR Pfam; PF18126; Mitoc_mL59; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW Transit peptide.
FT TRANSIT 1..?
FT /note="Mitochondrion"
FT CHAIN ?..145
FT /note="54S ribosomal protein L25, mitochondrial"
FT /id="PRO_0000351440"
FT REGION 123..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 145 AA; 17044 MW; CD93105C21842008 CRC64;
MPVFTKEALE RLPIQLGNFF KKFPPENPNA WTTNPNRQNP FLATRNPQNG LVINPYYSNR
RQAEIYKEAR LQNLDNLLPQ QMSWQKDSTR HILKGLLNPK GKISERKRDE ILENRRLKLS
ESLKKTSKFK NERQKASKIA KPSPF
