ID   RM28_DROME              Reviewed;         302 AA.
AC   Q9VMX0; Q8SXZ1;
DT   19-SEP-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=39S ribosomal protein L28, mitochondrial;
DE            Short=L28mt;
DE            Short=MRP-L28;
DE   Flags: Precursor;
GN   Name=mRpL28; ORFNames=CG3782;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley; TISSUE=Embryo;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins.
CC       {ECO:0000250|UniProtKB:Q13084}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q13084}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL28 family.
CC       {ECO:0000305}.
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DR   EMBL; AE014134; AAF52188.1; -; Genomic_DNA.
DR   EMBL; AY075494; AAL68304.1; -; mRNA.
DR   RefSeq; NP_001260063.1; NM_001273134.1.
DR   RefSeq; NP_608887.1; NM_135043.4.
DR   AlphaFoldDB; Q9VMX0; -.
DR   SMR; Q9VMX0; -.
DR   BioGRID; 59899; 1.
DR   IntAct; Q9VMX0; 1.
DR   STRING; 7227.FBpp0303669; -.
DR   PaxDb; Q9VMX0; -.
DR   PRIDE; Q9VMX0; -.
DR   DNASU; 33715; -.
DR   EnsemblMetazoa; FBtr0078996; FBpp0078635; FBgn0031660.
DR   EnsemblMetazoa; FBtr0331227; FBpp0303669; FBgn0031660.
DR   GeneID; 33715; -.
DR   KEGG; dme:Dmel_CG3782; -.
DR   CTD; 10573; -.
DR   FlyBase; FBgn0031660; mRpL28.
DR   VEuPathDB; VectorBase:FBgn0031660; -.
DR   eggNOG; KOG3279; Eukaryota.
DR   GeneTree; ENSGT00390000017359; -.
DR   HOGENOM; CLU_078055_0_0_1; -.
DR   InParanoid; Q9VMX0; -.
DR   OMA; LKNRACD; -.
DR   OrthoDB; 1558223at2759; -.
DR   PhylomeDB; Q9VMX0; -.
DR   Reactome; R-DME-5389840; Mitochondrial translation elongation.
DR   Reactome; R-DME-5419276; Mitochondrial translation termination.
DR   SignaLink; Q9VMX0; -.
DR   BioGRID-ORCS; 33715; 1 hit in 1 CRISPR screen.
DR   GenomeRNAi; 33715; -.
DR   PRO; PR:Q9VMX0; -.
DR   Proteomes; UP000000803; Chromosome 2L.
DR   Bgee; FBgn0031660; Expressed in adult hindgut (Drosophila) and 24 other tissues.
DR   ExpressionAtlas; Q9VMX0; baseline and differential.
DR   Genevisible; Q9VMX0; DM.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:FlyBase.
DR   GO; GO:0032543; P:mitochondrial translation; TAS:FlyBase.
DR   InterPro; IPR034704; L28p-like.
DR   InterPro; IPR026569; Ribo_L28/L24.
DR   PANTHER; PTHR13528; PTHR13528; 1.
DR   SUPFAM; SSF143800; SSF143800; 1.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..302
FT                   /note="39S ribosomal protein L28, mitochondrial"
FT                   /id="PRO_0000030508"
FT   CONFLICT        86..87
FT                   /note="IW -> MG (in Ref. 3; AAL68304)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   302 AA;  34950 MW;  D6BDDE8B868062FE CRC64;
     MAHATPQGVK LLNGWKRPGR FDKGLGAQLP EAYRKFWREW KLTTPAAVHY IPKEQQWERD
     EVTHAIKPVQ NIPLPLIDTP ESHRGIWGGE AVIKGFQKRE QTKRRVPHFW VPNLRRSVVH
     SHVLDCYMSV VVTERTLEQI HECHGFDHYL LKNRACDLRS ALALKLKREV LQALQNGVPA
     LADEPERQQE VLKEYRRYLE PYTPEEIDWY GHTYLEAIRK LQKQLREAEK VVPHKLEFRG
     KLIEQLRQAG ISEAGKLEKP DALAAESSVE HKDSDIEALT KLESSPSSSW LSKINPFGKK
     ET