RM34_MOUSE
ID RM34_MOUSE Reviewed; 92 AA.
AC Q99N91; Q3TDJ8;
DT 31-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=39S ribosomal protein L34, mitochondrial;
DE Short=L34mt;
DE Short=MRP-L34;
DE Flags: Precursor;
GN Name=Mrpl34;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=11279069; DOI=10.1074/jbc.m100432200;
RA Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A.,
RA Watanabe K.;
RT "Structural compensation for the deficit of rRNA with proteins in the
RT mammalian mitochondrial ribosome. Systematic analysis of protein components
RT of the large ribosomal subunit from mammalian mitochondria.";
RL J. Biol. Chem. 276:21724-21736(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J, and NOD; TISSUE=Kidney;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Liver;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC which comprises a 16S rRNA and about 50 distinct proteins.
CC {ECO:0000250|UniProtKB:Q9BQ48}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9BQ48}.
CC -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL34 family.
CC {ECO:0000305}.
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DR EMBL; AB049653; BAB40858.1; -; mRNA.
DR EMBL; AK018724; BAC25562.1; -; mRNA.
DR EMBL; AK170156; BAE41603.1; -; mRNA.
DR EMBL; BC052086; AAH52086.1; -; mRNA.
DR EMBL; BC056979; AAH56979.1; -; mRNA.
DR CCDS; CCDS40383.1; -.
DR RefSeq; NP_444392.1; NM_053162.2.
DR AlphaFoldDB; Q99N91; -.
DR SMR; Q99N91; -.
DR BioGRID; 220437; 22.
DR ComplexPortal; CPX-5302; 39S mitochondrial large ribosomal subunit.
DR STRING; 10090.ENSMUSP00000044497; -.
DR PhosphoSitePlus; Q99N91; -.
DR EPD; Q99N91; -.
DR MaxQB; Q99N91; -.
DR PaxDb; Q99N91; -.
DR PeptideAtlas; Q99N91; -.
DR PRIDE; Q99N91; -.
DR ProteomicsDB; 260979; -.
DR Antibodypedia; 43756; 84 antibodies from 21 providers.
DR DNASU; 94065; -.
DR Ensembl; ENSMUST00000048914; ENSMUSP00000044497; ENSMUSG00000034880.
DR GeneID; 94065; -.
DR KEGG; mmu:94065; -.
DR UCSC; uc009mdh.1; mouse.
DR CTD; 64981; -.
DR MGI; MGI:2137227; Mrpl34.
DR VEuPathDB; HostDB:ENSMUSG00000034880; -.
DR eggNOG; KOG4612; Eukaryota.
DR GeneTree; ENSGT00390000012240; -.
DR HOGENOM; CLU_2372198_0_0_1; -.
DR InParanoid; Q99N91; -.
DR OMA; WLQPRVW; -.
DR OrthoDB; 1644259at2759; -.
DR PhylomeDB; Q99N91; -.
DR TreeFam; TF324478; -.
DR Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 94065; 21 hits in 72 CRISPR screens.
DR ChiTaRS; Mrpl34; mouse.
DR PRO; PR:Q99N91; -.
DR Proteomes; UP000000589; Chromosome 8.
DR RNAct; Q99N91; protein.
DR Bgee; ENSMUSG00000034880; Expressed in right kidney and 259 other tissues.
DR Genevisible; Q99N91; MM.
DR GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR GO; GO:0003735; F:structural constituent of ribosome; ISO:MGI.
DR GO; GO:0032543; P:mitochondrial translation; IC:ComplexPortal.
DR GO; GO:0006412; P:translation; ISO:MGI.
DR InterPro; IPR000271; Ribosomal_L34.
DR PANTHER; PTHR14503; PTHR14503; 1.
DR Pfam; PF00468; Ribosomal_L34; 1.
DR TIGRFAMs; TIGR01030; rpmH_bact; 1.
PE 1: Evidence at protein level;
KW Mitochondrion; Phosphoprotein; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein; Transit peptide.
FT TRANSIT 1..46
FT /note="Mitochondrion"
FT /evidence="ECO:0000250|UniProtKB:A8NN94"
FT CHAIN 47..92
FT /note="39S ribosomal protein L34, mitochondrial"
FT /id="PRO_0000030521"
FT MOD_RES 71
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9BQ48"
SQ SEQUENCE 92 AA; 10531 MW; 5AC81C0DBDE22906 CRC64;
MAFLARCFGC QACRSVALLS GRYLQSRVWM GLPDSWPLLS LQQARGRARG NEYQPSNIKR
KHKHGWVRRL STPAGVQVIL RRMLKGRKSL SH
