ID   RM37_MOUSE              Reviewed;         423 AA.
AC   Q921S7;
DT   07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=39S ribosomal protein L37, mitochondrial;
DE            Short=L37mt;
DE            Short=MRP-L37;
DE   Flags: Precursor;
GN   Name=Mrpl37;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Liver, and Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=FVB/N; TISSUE=Colon, and Mammary tumor;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Pancreas, and
RC   Spleen;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins.
CC       {ECO:0000250|UniProtKB:Q9BZE1}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9BZE1}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mL37 family. {ECO:0000305}.
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DR   EMBL; AK161818; BAE36590.1; -; mRNA.
DR   EMBL; AK167461; BAE39546.1; -; mRNA.
DR   EMBL; BC011065; AAH11065.1; -; mRNA.
DR   EMBL; BC028257; AAH28257.1; -; mRNA.
DR   CCDS; CCDS18429.1; -.
DR   RefSeq; NP_079776.1; NM_025500.2.
DR   AlphaFoldDB; Q921S7; -.
DR   SMR; Q921S7; -.
DR   BioGRID; 207874; 33.
DR   ComplexPortal; CPX-5302; 39S mitochondrial large ribosomal subunit.
DR   STRING; 10090.ENSMUSP00000030365; -.
DR   iPTMnet; Q921S7; -.
DR   PhosphoSitePlus; Q921S7; -.
DR   SwissPalm; Q921S7; -.
DR   EPD; Q921S7; -.
DR   MaxQB; Q921S7; -.
DR   PaxDb; Q921S7; -.
DR   PeptideAtlas; Q921S7; -.
DR   PRIDE; Q921S7; -.
DR   ProteomicsDB; 260980; -.
DR   Antibodypedia; 19283; 80 antibodies from 23 providers.
DR   DNASU; 56280; -.
DR   Ensembl; ENSMUST00000030365; ENSMUSP00000030365; ENSMUSG00000028622.
DR   GeneID; 56280; -.
DR   KEGG; mmu:56280; -.
DR   UCSC; uc008tza.2; mouse.
DR   CTD; 51253; -.
DR   MGI; MGI:1926268; Mrpl37.
DR   VEuPathDB; HostDB:ENSMUSG00000028622; -.
DR   eggNOG; ENOG502QQAQ; Eukaryota.
DR   GeneTree; ENSGT00390000000867; -.
DR   HOGENOM; CLU_037022_1_0_1; -.
DR   InParanoid; Q921S7; -.
DR   OMA; TTWNRES; -.
DR   OrthoDB; 1281130at2759; -.
DR   PhylomeDB; Q921S7; -.
DR   TreeFam; TF323297; -.
DR   Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR   Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR   BioGRID-ORCS; 56280; 26 hits in 75 CRISPR screens.
DR   PRO; PR:Q921S7; -.
DR   Proteomes; UP000000589; Chromosome 4.
DR   RNAct; Q921S7; protein.
DR   Bgee; ENSMUSG00000028622; Expressed in undifferentiated genital tubercle and 255 other tissues.
DR   Genevisible; Q921S7; MM.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005761; C:mitochondrial ribosome; ISS:MGI.
DR   GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0032543; P:mitochondrial translation; IC:ComplexPortal.
DR   InterPro; IPR010793; Ribosomal_L37/S30.
DR   Pfam; PF07147; PDCD9; 1.
PE   1: Evidence at protein level;
KW   Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   Transit peptide.
FT   TRANSIT         1..29
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250"
FT   CHAIN           30..423
FT                   /note="39S ribosomal protein L37, mitochondrial"
FT                   /id="PRO_0000045906"
SQ   SEQUENCE   423 AA;  48341 MW;  1B16CCF356E8F685 CRC64;
     MALASGPALR ALAGSGRLGL GGYGTPKRGA YEWGVRSTRK PEPRPLDRVY EIPGLEPITY
     EGKKHFVPWL ARPIFPPWER GWNDPRFHRA APIHEQTLYK EEPCYIFHQR CRLLEGMKQA
     LWLTKTKLIE GLPKKVLSLV DDPANHIENQ EQRVLDIISH ARLWHSTEDI PKRETYCPLI
     VDSLIQLCKS QILKHPSLAR RTSAQNCTLA TTWNRESLLL QVRGTSSTIL SAKDPLPVIA
     SREEVEATRS HVLETFYPIS PTIDLQECHV YEVKDDTGFQ EGYPYPHPHT LYFLEKANLR
     PQRFLPEQLR AKMLLFAFAN ALAQARLLYG NTAKVLEQPI VVQSVGTDGR VFQFLVLQLN
     TTDLASSEGV KNLVWTDSDQ LLYRHFWCRP VIKKKVVVEP VGPVDFQPET FRKFLALYLH
     GVV