RM40_RAT
ID RM40_RAT Reviewed; 206 AA.
AC P83565; Q4V8A4;
DT 19-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=39S ribosomal protein L40, mitochondrial;
DE Short=L40mt;
DE Short=MRP-L40;
DE Flags: Precursor;
GN Name=Mrpl40;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000305};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2] {ECO:0000305}
RP PROTEIN SEQUENCE OF 47-75, AND SUBCELLULAR LOCATION.
RX PubMed=9857009; DOI=10.1074/jbc.273.52.34828;
RA Goldschmidt-Reisin S., Kitakawa M., Herfurth E., Wittmann-Liebold B.,
RA Grohmann L., Graack H.-R.;
RT "Mammalian mitochondrial ribosomal proteins. N-terminal amino acid
RT sequencing, characterization, and identification of corresponding gene
RT sequences.";
RL J. Biol. Chem. 273:34828-34836(1998).
CC -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC which comprises a 16S rRNA and about 50 distinct proteins.
CC {ECO:0000250|UniProtKB:Q9NQ50}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:9857009}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mL40 family. {ECO:0000305}.
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DR EMBL; BC097472; AAH97472.1; -; mRNA.
DR RefSeq; NP_001020036.1; NM_001024865.1.
DR AlphaFoldDB; P83565; -.
DR SMR; P83565; -.
DR STRING; 10116.ENSRNOP00000065376; -.
DR jPOST; P83565; -.
DR PaxDb; P83565; -.
DR PRIDE; P83565; -.
DR Ensembl; ENSRNOT00000071159; ENSRNOP00000065376; ENSRNOG00000049686.
DR GeneID; 287962; -.
DR KEGG; rno:287962; -.
DR CTD; 64976; -.
DR RGD; 1565444; Mrpl40.
DR eggNOG; KOG4778; Eukaryota.
DR GeneTree; ENSGT00390000010239; -.
DR HOGENOM; CLU_087493_0_0_1; -.
DR InParanoid; P83565; -.
DR OMA; ATPPIKD; -.
DR OrthoDB; 1524457at2759; -.
DR PhylomeDB; P83565; -.
DR Reactome; R-RNO-5389840; Mitochondrial translation elongation.
DR Reactome; R-RNO-5419276; Mitochondrial translation termination.
DR PRO; PR:P83565; -.
DR Proteomes; UP000002494; Chromosome 11.
DR Bgee; ENSRNOG00000049686; Expressed in heart and 20 other tissues.
DR Genevisible; P83565; RN.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005761; C:mitochondrial ribosome; IDA:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; ISO:RGD.
DR InterPro; IPR039145; MRPL40.
DR InterPro; IPR019192; Ribosomal_L28/L40_mit.
DR PANTHER; PTHR13359; PTHR13359; 1.
DR Pfam; PF09812; MRP-L28; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Mitochondrion; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein; Transit peptide.
FT TRANSIT 1..46
FT /note="Mitochondrion"
FT /evidence="ECO:0000269|PubMed:9857009"
FT CHAIN 47..206
FT /note="39S ribosomal protein L40, mitochondrial"
FT /id="PRO_0000087687"
FT REGION 170..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 56
FT /note="V -> Y (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 206 AA; 24397 MW; 500D285FBB8B1E71 CRC64;
MATAAMLCAA RALRPRSWIP GTCQAQVRHT HQRASLLSFW ELIPMRAEPL RKKKKVDPRK
DQAAKDRLKK RIRKLERASQ ELVPIEDFIT PVRFLDKSRQ RPQEEHSFEE SERRALLLKR
WALYKQQEHE MERDAIRAML EAQQEALEQL KLESTELYAE AIKRDTSLFP FEKEGPHYTP
PVPNYQAPEG RYNDITKVYT QVEFKR
