RM42_RAT
ID RM42_RAT Reviewed; 141 AA.
AC P0C2B9;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=28S ribosomal protein L42, mitochondrial;
DE Short=L42mt;
DE Short=MRP-L42;
DE AltName: Full=28S ribosomal protein S32, mitochondrial;
DE Short=MRP-S32;
DE Short=S32mt;
DE Flags: Precursor;
GN Name=Mrpl42; Synonyms=Mrps32;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway;
RX PubMed=15057822; DOI=10.1038/nature02426;
RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA Mockrin S., Collins F.S.;
RT "Genome sequence of the Brown Norway rat yields insights into mammalian
RT evolution.";
RL Nature 428:493-521(2004).
RN [2]
RP PROTEIN SEQUENCE OF 32-54, AND SUBCELLULAR LOCATION.
RX PubMed=9857009; DOI=10.1074/jbc.273.52.34828;
RA Goldschmidt-Reisin S., Kitakawa M., Herfurth E., Wittmann-Liebold B.,
RA Grohmann L., Graack H.-R.;
RT "Mammalian mitochondrial ribosomal proteins. N-terminal amino acid
RT sequencing, characterization, and identification of corresponding gene
RT sequences.";
RL J. Biol. Chem. 273:34828-34836(1998).
CC -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC which comprises a 16S rRNA and about 50 distinct proteins. Component of
CC the mitochondrial ribosome small subunit (28S) which comprises a 12S
CC rRNA and about 30 distinct proteins. {ECO:0000250|UniProtKB:Q9Y6G3}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:9857009}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mL42 family. {ECO:0000305}.
CC -!- CAUTION: Has been found in the mitochondrial ribosome large and small
CC subunits. {ECO:0000305}.
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DR EMBL; AABR03088058; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_008760533.1; XM_008762311.2.
DR RefSeq; XP_008767800.1; XM_008769578.2.
DR AlphaFoldDB; P0C2B9; -.
DR SMR; P0C2B9; -.
DR STRING; 10116.ENSRNOP00000061916; -.
DR jPOST; P0C2B9; -.
DR PaxDb; P0C2B9; -.
DR PRIDE; P0C2B9; -.
DR Ensembl; ENSRNOT00000011332; ENSRNOP00000089938; ENSRNOG00000025964.
DR GeneID; 103691922; -.
DR UCSC; RGD:1304915; rat.
DR RGD; 1304915; Mrpl42.
DR eggNOG; KOG4106; Eukaryota.
DR GeneTree; ENSGT00390000010491; -.
DR InParanoid; P0C2B9; -.
DR OrthoDB; 1604174at2759; -.
DR PhylomeDB; P0C2B9; -.
DR TreeFam; TF324368; -.
DR Reactome; R-RNO-5389840; Mitochondrial translation elongation.
DR Reactome; R-RNO-5419276; Mitochondrial translation termination.
DR PRO; PR:P0C2B9; -.
DR Proteomes; UP000002494; Chromosome 13.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; ISO:RGD.
DR InterPro; IPR019346; MRPL42.
DR PANTHER; PTHR13450; PTHR13450; 1.
DR Pfam; PF10210; MRP-S32; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Mitochondrion; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein; Transit peptide.
FT TRANSIT 1..31
FT /note="Mitochondrion"
FT /evidence="ECO:0000269|PubMed:9857009"
FT CHAIN 32..141
FT /note="28S ribosomal protein L42, mitochondrial"
FT /id="PRO_0000273238"
SQ SEQUENCE 141 AA; 16469 MW; BEB183B198A67662 CRC64;
MTAAVKWAVS HRTIWRHLFP IQNGAISSAC HKSTYSSLPD DYNCKVELAL TSDGRTIVCY
HPSVDVPYEH TKPIPHPDLL HNNEETHEQI LRTKLEGNHK HLEQGPMIEQ LSKVFFTTKH
RWYPHGQYHR CRKKLNPPKD R
