ID   RM44_BOVIN              Reviewed;         332 AA.
AC   Q2KIS2;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=39S ribosomal protein L44, mitochondrial;
DE            Short=L44mt;
DE            Short=MRP-L44;
DE            EC=3.1.26.-;
DE   Flags: Precursor;
GN   Name=MRPL44;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Testis;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the 39S subunit of mitochondrial ribosome. May
CC       have a function in the assembly/stability of nascent mitochondrial
CC       polypeptides exiting the ribosome. {ECO:0000250|UniProtKB:Q9H9J2}.
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins.
CC       {ECO:0000250|UniProtKB:Q9H9J2}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9H9J2}.
CC   -!- SIMILARITY: Belongs to the ribonuclease III family. Mitochondrion-
CC       specific ribosomal protein mL44 subfamily. {ECO:0000305}.
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DR   EMBL; BC112531; AAI12532.1; -; mRNA.
DR   RefSeq; NP_001039786.1; NM_001046321.2.
DR   AlphaFoldDB; Q2KIS2; -.
DR   SMR; Q2KIS2; -.
DR   STRING; 9913.ENSBTAP00000015301; -.
DR   PaxDb; Q2KIS2; -.
DR   PRIDE; Q2KIS2; -.
DR   GeneID; 532389; -.
DR   KEGG; bta:532389; -.
DR   CTD; 65080; -.
DR   eggNOG; KOG3769; Eukaryota.
DR   HOGENOM; CLU_058895_0_0_1; -.
DR   InParanoid; Q2KIS2; -.
DR   OrthoDB; 877695at2759; -.
DR   TreeFam; TF324185; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0070125; P:mitochondrial translational elongation; ISS:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR   CDD; cd19874; DSRM_MRPL44; 1.
DR   Gene3D; 1.10.1520.10; -; 1.
DR   InterPro; IPR044444; MRPL44_DSRM.
DR   InterPro; IPR011907; RNase_III.
DR   InterPro; IPR036389; RNase_III_sf.
DR   PANTHER; PTHR11207; PTHR11207; 1.
DR   SUPFAM; SSF69065; SSF69065; 1.
PE   2: Evidence at transcript level;
KW   Endonuclease; Hydrolase; Mitochondrion; Nuclease; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein; RNA-binding; Transit peptide.
FT   TRANSIT         1..30
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..332
FT                   /note="39S ribosomal protein L44, mitochondrial"
FT                   /id="PRO_0000253620"
FT   DOMAIN          86..228
FT                   /note="RNase III"
FT   DOMAIN          236..306
FT                   /note="DRBM"
SQ   SEQUENCE   332 AA;  37412 MW;  B587B2C2C17F04F8 CRC64;
     MASGLTRLLL RGPRCLLATA GLTLIPPVRG VKKGFRAAFR FQKELERWRL LRCPPPPVRR
     SEKPNWDYHA EIQAFGPRLQ ETFSLDLLKT AFVNSCYIKS EEAKRQKLGI EKEAVLLNLK
     DNQELSEQGT SFSQTCLTQF FEDAFPDLPT EGVKSLVDYL TGEEVVCHVA RNLAVEQLTL
     SADFPVPPAV LRQTFFAVIG ALLHSSGPER TSLFIRDFLI TQMTGKELFE IWKIINPMGL
     LVQELKKRNI SVPESRLTRQ SGSTTALPVY FVGLYCDKKL IAEGPGETVL VAEEEAARVA
     LRKLYGFTEN RQPWDYSRPK EPVRAEKTIA AS