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RM44_PONAB
ID   RM44_PONAB              Reviewed;         332 AA.
AC   Q5REY8;
DT   21-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=39S ribosomal protein L44, mitochondrial;
DE            Short=L44mt;
DE            Short=MRP-L44;
DE            EC=3.1.26.-;
DE   Flags: Precursor;
GN   Name=MRPL44;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the 39S subunit of mitochondrial ribosome. May
CC       have a function in the assembly/stability of nascent mitochondrial
CC       polypeptides exiting the ribosome. {ECO:0000250|UniProtKB:Q9H9J2}.
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins.
CC       {ECO:0000250|UniProtKB:Q9H9J2}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9H9J2}.
CC   -!- SIMILARITY: Belongs to the ribonuclease III family. Mitochondrion-
CC       specific ribosomal protein mL44 subfamily. {ECO:0000305}.
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DR   EMBL; CR857375; CAH89669.1; -; mRNA.
DR   RefSeq; NP_001127183.1; NM_001133711.1.
DR   AlphaFoldDB; Q5REY8; -.
DR   SMR; Q5REY8; -.
DR   STRING; 9601.ENSPPYP00000014783; -.
DR   GeneID; 100174237; -.
DR   KEGG; pon:100174237; -.
DR   CTD; 65080; -.
DR   eggNOG; KOG3769; Eukaryota.
DR   InParanoid; Q5REY8; -.
DR   OrthoDB; 877695at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0070125; P:mitochondrial translational elongation; ISS:UniProtKB.
DR   GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR   CDD; cd19874; DSRM_MRPL44; 1.
DR   Gene3D; 1.10.1520.10; -; 1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR044444; MRPL44_DSRM.
DR   InterPro; IPR011907; RNase_III.
DR   InterPro; IPR036389; RNase_III_sf.
DR   PANTHER; PTHR11207; PTHR11207; 1.
DR   SUPFAM; SSF69065; SSF69065; 1.
DR   PROSITE; PS50137; DS_RBD; 1.
PE   2: Evidence at transcript level;
KW   Endonuclease; Hydrolase; Mitochondrion; Nuclease; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein; RNA-binding; Transit peptide.
FT   TRANSIT         1..30
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250"
FT   CHAIN           31..332
FT                   /note="39S ribosomal protein L44, mitochondrial"
FT                   /id="PRO_0000030823"
FT   DOMAIN          86..228
FT                   /note="RNase III"
FT   DOMAIN          236..306
FT                   /note="DRBM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00266"
SQ   SEQUENCE   332 AA;  37549 MW;  3B59F08D643460D0 CRC64;
     MASGLVRLLQ QGPRCLLAPV APKLVPPVRG VKRGFRAAFR FQKELERQRL LRCPPPPVRR
     SEKPNWDYHA EIQAFGHRLQ ENFSLDLLKT AFVNSCYIKS EEAKRQQLGI EKEAVLLNLK
     SNQELSEQGT SFSQTCLTQF LEDEYPDLPT EGIKNLVEFL TGEDVVCHVA RNLAVEQLTL
     SEEFPVPPTV LQQTFFAVIG ALLQSSGPER TALFIRDFLI TQMTGKELFE MWKIINPMGL
     LVEELKKRNI SAPESRLTRQ SGGTTALPLY FVGLYCDKKL IAEGPGETVL VAEEEAARVA
     LRKLYGFTEN RRPWNYSKPK ETLRAEKSIT AS
 
 
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