ID   RM46_BOVIN              Reviewed;         277 AA.
AC   Q3SZ22;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=39S ribosomal protein L46, mitochondrial;
DE            Short=L46mt;
DE            Short=MRP-L46;
DE   Flags: Precursor;
GN   Name=MRPL46;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Heart ventricle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins.
CC       {ECO:0000250|UniProtKB:Q9H2W6}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q9H2W6}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mL46 family. {ECO:0000305}.
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DR   EMBL; BC103228; AAI03229.1; -; mRNA.
DR   RefSeq; NP_001029884.1; NM_001034712.1.
DR   AlphaFoldDB; Q3SZ22; -.
DR   SMR; Q3SZ22; -.
DR   STRING; 9913.ENSBTAP00000026420; -.
DR   PaxDb; Q3SZ22; -.
DR   PRIDE; Q3SZ22; -.
DR   Ensembl; ENSBTAT00000026420; ENSBTAP00000026420; ENSBTAG00000019830.
DR   GeneID; 540720; -.
DR   KEGG; bta:540720; -.
DR   CTD; 26589; -.
DR   VEuPathDB; HostDB:ENSBTAG00000019830; -.
DR   VGNC; VGNC:31641; MRPL46.
DR   eggNOG; KOG4548; Eukaryota.
DR   GeneTree; ENSGT00390000015400; -.
DR   InParanoid; Q3SZ22; -.
DR   OMA; NNMEAKF; -.
DR   OrthoDB; 1527405at2759; -.
DR   Proteomes; UP000009136; Chromosome 21.
DR   Bgee; ENSBTAG00000019830; Expressed in tongue muscle and 106 other tissues.
DR   GO; GO:0030054; C:cell junction; IEA:Ensembl.
DR   GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   CDD; cd04661; MRP_L46; 1.
DR   InterPro; IPR033650; MRP_L46_NUDIX.
DR   InterPro; IPR040008; MRPL46.
DR   InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR   InterPro; IPR021757; Ribosomal_L46_N.
DR   PANTHER; PTHR13124; PTHR13124; 1.
DR   Pfam; PF11788; MRP-L46; 1.
DR   SUPFAM; SSF55811; SSF55811; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Mitochondrion; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..277
FT                   /note="39S ribosomal protein L46, mitochondrial"
FT                   /id="PRO_0000273554"
FT   MOD_RES         228
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H2W6"
SQ   SEQUENCE   277 AA;  31726 MW;  E79071D60DCE9A82 CRC64;
     MAAPTRRTVL GLARCWRRFE SPWSLGSRSL TLAAAPSNSA SPWRLLGALC LQRPPLVSKQ
     LTPMQEEMAA LLQQMEIERS LYSDHELRAL DEAEQLEKKK SDLYEEKDEK NILLVQDLED
     MWEQKFLQFK PGARITDADV KNDRSSLHRK LDRNLILLVK DKLGDQDVWM LPQAEWQPGE
     TLRQTAERTL ATLSENNLEA KFLGNAPCGH YKFKFPQAVR AEGSLGAKIF FFKALLLTGD
     FSPAVEKGRH VWASKEELGD YLKPKYLAQV RRFLLDL