RM49_DROME
ID RM49_DROME Reviewed; 179 AA.
AC Q9VYI3;
DT 16-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Probable 39S ribosomal protein L49, mitochondrial;
DE Short=L49mt;
DE Short=MRP-L49;
GN Name=mRpL49; ORFNames=CG4647;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
CC -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC which comprises a 16S rRNA and about 50 distinct proteins.
CC {ECO:0000250|UniProtKB:Q13405}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q13405}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mL49 family. {ECO:0000305}.
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DR EMBL; AE014298; AAF48212.1; -; Genomic_DNA.
DR RefSeq; NP_001285170.1; NM_001298241.1.
DR RefSeq; NP_572839.1; NM_132611.3.
DR AlphaFoldDB; Q9VYI3; -.
DR SMR; Q9VYI3; -.
DR STRING; 7227.FBpp0073524; -.
DR PaxDb; Q9VYI3; -.
DR EnsemblMetazoa; FBtr0073691; FBpp0073524; FBgn0030433.
DR EnsemblMetazoa; FBtr0343185; FBpp0309878; FBgn0030433.
DR GeneID; 32242; -.
DR KEGG; dme:Dmel_CG4647; -.
DR CTD; 740; -.
DR FlyBase; FBgn0030433; mRpL49.
DR VEuPathDB; VectorBase:FBgn0030433; -.
DR eggNOG; KOG4034; Eukaryota.
DR GeneTree; ENSGT00390000017253; -.
DR HOGENOM; CLU_085757_2_0_1; -.
DR InParanoid; Q9VYI3; -.
DR OMA; NPPEWKY; -.
DR OrthoDB; 1534017at2759; -.
DR PhylomeDB; Q9VYI3; -.
DR Reactome; R-DME-5389840; Mitochondrial translation elongation.
DR Reactome; R-DME-5419276; Mitochondrial translation termination.
DR BioGRID-ORCS; 32242; 1 hit in 1 CRISPR screen.
DR GenomeRNAi; 32242; -.
DR PRO; PR:Q9VYI3; -.
DR Proteomes; UP000000803; Chromosome X.
DR Bgee; FBgn0030433; Expressed in mouthpart and 25 other tissues.
DR ExpressionAtlas; Q9VYI3; baseline and differential.
DR Genevisible; Q9VYI3; DM.
DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; ISS:FlyBase.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR GO; GO:0032543; P:mitochondrial translation; TAS:FlyBase.
DR InterPro; IPR007740; Ribosomal_L49/IMG2.
DR InterPro; IPR001950; SUI1.
DR PANTHER; PTHR13477; PTHR13477; 1.
DR Pfam; PF05046; Img2; 1.
DR PROSITE; PS50296; SUI1; 1.
PE 3: Inferred from homology;
KW Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT CHAIN 1..179
FT /note="Probable 39S ribosomal protein L49, mitochondrial"
FT /id="PRO_0000207669"
SQ SEQUENCE 179 AA; 20658 MW; 5B8BEAE6A3E5A9FF CRC64;
MATSAKLMLG SGLCQKLSQL TRQIHMQPAL MSSFRSSREV QELDKYPEVE VVANPPEWRF
VERLLPAKTV PQPVEKPKYP SGWQPQKEDG SELGYHVART KNHMVPVYLH TRFRGQRRIT
VVRRVQGDIW TLEKDLRAVV EQSRNGKVCA TRINELSGQI HFHGDHVDVL RDYLKEKGF
