ID   RM52_DROME              Reviewed;         126 AA.
AC   Q7JWG9; A1Z732;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=39S ribosomal protein L52, mitochondrial;
DE            Short=L52mt;
DE            Short=MRP-L52;
DE   Flags: Precursor;
GN   Name=mRpL52; ORFNames=CG1577;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley; TISSUE=Head;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins.
CC       {ECO:0000250|UniProtKB:Q86TS9}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q86TS9}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mL52 family. {ECO:0000305}.
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DR   EMBL; AE013599; AAF59209.1; -; Genomic_DNA.
DR   EMBL; AY113553; AAM29558.1; -; mRNA.
DR   RefSeq; NP_610313.1; NM_136469.4.
DR   AlphaFoldDB; Q7JWG9; -.
DR   SMR; Q7JWG9; -.
DR   BioGRID; 61585; 1.
DR   IntAct; Q7JWG9; 1.
DR   STRING; 7227.FBpp0088016; -.
DR   PaxDb; Q7JWG9; -.
DR   PRIDE; Q7JWG9; -.
DR   DNASU; 35711; -.
DR   EnsemblMetazoa; FBtr0088942; FBpp0088016; FBgn0033208.
DR   GeneID; 35711; -.
DR   KEGG; dme:Dmel_CG1577; -.
DR   CTD; 122704; -.
DR   FlyBase; FBgn0033208; mRpL52.
DR   VEuPathDB; VectorBase:FBgn0033208; -.
DR   eggNOG; ENOG502S4I0; Eukaryota.
DR   GeneTree; ENSGT00390000005763; -.
DR   HOGENOM; CLU_135844_1_0_1; -.
DR   InParanoid; Q7JWG9; -.
DR   OMA; PLGANQK; -.
DR   OrthoDB; 1623574at2759; -.
DR   PhylomeDB; Q7JWG9; -.
DR   Reactome; R-DME-5389840; Mitochondrial translation elongation.
DR   Reactome; R-DME-5419276; Mitochondrial translation termination.
DR   SignaLink; Q7JWG9; -.
DR   BioGRID-ORCS; 35711; 1 hit in 1 CRISPR screen.
DR   GenomeRNAi; 35711; -.
DR   PRO; PR:Q7JWG9; -.
DR   Proteomes; UP000000803; Chromosome 2R.
DR   Bgee; FBgn0033208; Expressed in ovary and 34 other tissues.
DR   ExpressionAtlas; Q7JWG9; baseline and differential.
DR   Genevisible; Q7JWG9; DM.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0032543; P:mitochondrial translation; TAS:FlyBase.
DR   GO; GO:0006412; P:translation; ISS:UniProtKB.
DR   InterPro; IPR034596; MRPL52.
DR   PANTHER; PTHR34090; PTHR34090; 1.
DR   Pfam; PF18699; MRPL52; 1.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   Transit peptide.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..126
FT                   /note="39S ribosomal protein L52, mitochondrial"
FT                   /id="PRO_0000273096"
SQ   SEQUENCE   126 AA;  14187 MW;  6D111B9AF1FADCD0 CRC64;
     MLKITKICLA SSATSTAQRS IALTAPRAID QKWRAAKGLP ENPNAFGPLT NLPDYTYLDG
     RPTPLGANQK RRLIKQQEIA TRIVELSGEL EFAKQRHERL KANAESEKQR LIRSKLKPKG
     HFLLKK