ID   RM54_MOUSE              Reviewed;         135 AA.
AC   Q9CPW3;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=39S ribosomal protein L54, mitochondrial;
DE            Short=L54mt;
DE            Short=MRP-L54;
DE   Flags: Precursor;
GN   Name=Mrpl54;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Embryo, and Tongue;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas,
RC   Spleen, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins.
CC       {ECO:0000250|UniProtKB:Q6P161}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q6P161}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mL54 family. {ECO:0000305}.
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DR   EMBL; AK003225; BAB22654.1; -; mRNA.
DR   EMBL; AK009657; BAB26421.1; -; mRNA.
DR   EMBL; BC056985; AAH56985.1; -; mRNA.
DR   CCDS; CCDS24049.1; -.
DR   RefSeq; NP_079593.1; NM_025317.2.
DR   AlphaFoldDB; Q9CPW3; -.
DR   SMR; Q9CPW3; -.
DR   BioGRID; 211175; 9.
DR   ComplexPortal; CPX-5302; 39S mitochondrial large ribosomal subunit.
DR   STRING; 10090.ENSMUSP00000039951; -.
DR   PhosphoSitePlus; Q9CPW3; -.
DR   EPD; Q9CPW3; -.
DR   MaxQB; Q9CPW3; -.
DR   PaxDb; Q9CPW3; -.
DR   PeptideAtlas; Q9CPW3; -.
DR   PRIDE; Q9CPW3; -.
DR   ProteomicsDB; 299912; -.
DR   Antibodypedia; 23347; 178 antibodies from 23 providers.
DR   DNASU; 66047; -.
DR   Ensembl; ENSMUST00000046114; ENSMUSP00000039951; ENSMUSG00000034932.
DR   GeneID; 66047; -.
DR   KEGG; mmu:66047; -.
DR   UCSC; uc007ggy.1; mouse.
DR   CTD; 116541; -.
DR   MGI; MGI:1913297; Mrpl54.
DR   VEuPathDB; HostDB:ENSMUSG00000034932; -.
DR   eggNOG; KOG3435; Eukaryota.
DR   GeneTree; ENSGT00390000001201; -.
DR   HOGENOM; CLU_143073_1_1_1; -.
DR   InParanoid; Q9CPW3; -.
DR   OMA; WLFQMNV; -.
DR   OrthoDB; 1538612at2759; -.
DR   PhylomeDB; Q9CPW3; -.
DR   TreeFam; TF314007; -.
DR   Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR   Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR   BioGRID-ORCS; 66047; 14 hits in 73 CRISPR screens.
DR   ChiTaRS; Mrpl54; mouse.
DR   PRO; PR:Q9CPW3; -.
DR   Proteomes; UP000000589; Chromosome 10.
DR   RNAct; Q9CPW3; protein.
DR   Bgee; ENSMUSG00000034932; Expressed in right kidney and 273 other tissues.
DR   Genevisible; Q9CPW3; MM.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IC:ComplexPortal.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0032543; P:mitochondrial translation; IC:ComplexPortal.
DR   InterPro; IPR013870; Ribosomal_L37_mit.
DR   PANTHER; PTHR28595; PTHR28595; 1.
DR   Pfam; PF08561; Ribosomal_L37; 1.
PE   1: Evidence at protein level;
KW   Mitochondrion; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW   Transit peptide.
FT   TRANSIT         1..14
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           15..135
FT                   /note="39S ribosomal protein L54, mitochondrial"
FT                   /id="PRO_0000278281"
SQ   SEQUENCE   135 AA;  15422 MW;  F0A200D5BD74334C CRC64;
     MAAAHLLRAS RVWARWHPRA LPVLRRPGGF SIREYAKKPV GKGGKGGVAA EALKDPEVCT
     DPTQLTTHAM GVNIYKEGQD VALKADSEYP TWLFQVNLGP PKKLEELEPE SREYWRLLRK
     QNIWRHNRLS KNKKL