ID   RMD1_BOVIN              Reviewed;         317 AA.
AC   Q32KL4;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Regulator of microtubule dynamics protein 1;
DE            Short=RMD-1;
DE   AltName: Full=Protein FAM82B;
GN   Name=RMDN1; Synonyms=FAM82B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts with microtubules. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm,
CC       cytoskeleton, spindle {ECO:0000250}. Cytoplasm, cytoskeleton, spindle
CC       pole {ECO:0000250}. Note=In interphase localizes in the cytoplasm, and
CC       during mitosis localizes to the spindle microtubules and spindle poles.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RMDN family. {ECO:0000305}.
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DR   EMBL; BC110037; AAI10038.1; -; mRNA.
DR   RefSeq; NP_001032689.1; NM_001037600.2.
DR   AlphaFoldDB; Q32KL4; -.
DR   SMR; Q32KL4; -.
DR   STRING; 9913.ENSBTAP00000020889; -.
DR   PaxDb; Q32KL4; -.
DR   PRIDE; Q32KL4; -.
DR   Ensembl; ENSBTAT00000020889; ENSBTAP00000020889; ENSBTAG00000015734.
DR   GeneID; 513788; -.
DR   KEGG; bta:513788; -.
DR   CTD; 51115; -.
DR   VEuPathDB; HostDB:ENSBTAG00000015734; -.
DR   eggNOG; ENOG502QSJV; Eukaryota.
DR   GeneTree; ENSGT00950000182992; -.
DR   HOGENOM; CLU_046369_1_1_1; -.
DR   InParanoid; Q32KL4; -.
DR   OMA; KDVEILW; -.
DR   OrthoDB; 1380644at2759; -.
DR   TreeFam; TF315854; -.
DR   Proteomes; UP000009136; Chromosome 14.
DR   Bgee; ENSBTAG00000015734; Expressed in oocyte and 104 other tissues.
DR   ExpressionAtlas; Q32KL4; baseline.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0097431; C:mitotic spindle pole; IBA:GO_Central.
DR   GO; GO:0005876; C:spindle microtubule; IBA:GO_Central.
DR   GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoskeleton; Microtubule; Reference proteome; Repeat;
KW   TPR repeat.
FT   CHAIN           1..317
FT                   /note="Regulator of microtubule dynamics protein 1"
FT                   /id="PRO_0000346794"
FT   REPEAT          171..207
FT                   /note="TPR 1"
FT   REPEAT          225..261
FT                   /note="TPR 2"
FT   MOD_RES         168
FT                   /note="N6-succinyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9DCV4"
SQ   SEQUENCE   317 AA;  35923 MW;  6AA5DD7E9F704B0F CRC64;
     MALAVRFWCL FPVGRSAAWG LRLPAGAAGS RGQRVPWRLG ASEAMGNSGT FKRSLLFSAL
     SYLGFETYQV ISQAVLVHAA AKVFEIEEVL EQADYLYESG ETEKLYQLLT QYKESEDAEL
     LWRLARASRD VAQLSGTSEE EKKFLVYEAL EYAKRALEKN ESSCAAHKWY AICIGDVGDY
     EGIKAKIANA YIIKEHFEKA IELNPKDATS IHLMGIWCYT VAEMPWYQRR IAKVLFATPP
     GSTYEEALGY FHRAEQVDPN FYSKNLLLLG KTYLKLHNKK LAAFWLTKAK DYPAHTEEDK
     QIQTEAAQLL RGFSDKN