ID   RMD1_PONAB              Reviewed;         314 AA.
AC   Q5R8E4;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Regulator of microtubule dynamics protein 1;
DE            Short=RMD-1;
DE   AltName: Full=Protein FAM82B;
GN   Name=RMDN1; Synonyms=FAM82B;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts with microtubules. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton,
CC       spindle {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole
CC       {ECO:0000250}. Note=In interphase localizes in the cytoplasm, and
CC       during mitosis localizes to the spindle microtubules and spindle poles.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RMDN family. {ECO:0000305}.
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DR   EMBL; CR859808; CAH91966.1; -; mRNA.
DR   RefSeq; NP_001126139.1; NM_001132667.1.
DR   AlphaFoldDB; Q5R8E4; -.
DR   SMR; Q5R8E4; -.
DR   PRIDE; Q5R8E4; -.
DR   GeneID; 100173097; -.
DR   KEGG; pon:100173097; -.
DR   CTD; 51115; -.
DR   eggNOG; ENOG502QSJV; Eukaryota.
DR   InParanoid; Q5R8E4; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoskeleton; Microtubule; Reference proteome; Repeat;
KW   TPR repeat.
FT   CHAIN           1..314
FT                   /note="Regulator of microtubule dynamics protein 1"
FT                   /id="PRO_0000187182"
FT   REPEAT          168..204
FT                   /note="TPR 1"
FT   REPEAT          222..258
FT                   /note="TPR 2"
FT   MOD_RES         165
FT                   /note="N6-succinyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9DCV4"
SQ   SEQUENCE   314 AA;  35709 MW;  3C1B390BBC1816AE CRC64;
     MALAARLWRF LPFRRGAAPG SLLSAGTSGS RGHCGPCRLR GFEVMGNPGT FKRGLLLSAL
     SYLGFETYQV ISQAAVVHAT AKVEEILEQA DYLCESGETE KLYQLLTQYK ESEDAELLWR
     LARASRDVAQ LSRTSEEEKK LLVYEALEYA KRALEKNESS FAAHKWYAIC LSDVGDYEGI
     KAKIANAYII KEHFEKAIEL NPKDATSIHL MGIWCYTFAE MPWYQRRIAK MLFATPPSST
     YEKALSYFHR AEQVDPNFYS KNLLLLGKTY LKLHNKKLAA FWLMKAKDYP AHTEEDKQIQ
     TEAAQLLTSF SEKN