RMD2_HUMAN
ID RMD2_HUMAN Reviewed; 410 AA.
AC Q96LZ7; A9UMZ7; A9UN00; Q4ZG33; Q6UXN4; Q8N657; Q8N9A2; Q8NCV6; Q8NHM0;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 2.
DT 03-AUG-2022, entry version 154.
DE RecName: Full=Regulator of microtubule dynamics protein 2;
DE Short=RMD-2;
DE Short=hRMD-2;
DE AltName: Full=Protein FAM82A1;
GN Name=RMDN2; Synonyms=FAM82A, FAM82A1; ORFNames=BLOCK18, UNQ9371/PRO34163;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3), AND VARIANT
RP ASP-259.
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RX PubMed=12975309; DOI=10.1101/gr.1293003;
RA Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J.,
RA Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P.,
RA Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A.,
RA Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D.,
RA Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L.,
RA Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C.,
RA Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J.,
RA Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.;
RT "The secreted protein discovery initiative (SPDI), a large-scale effort to
RT identify novel human secreted and transmembrane proteins: a bioinformatics
RT assessment.";
RL Genome Res. 13:2265-2270(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
RA Guo J.H., Yu L.;
RL Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [7]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 152-410.
RA Gorry M.C., Zhang Y., Marks J.J., Suppe B., Hart P.S., Cortelli J.R.,
RA Pallos D., Hart T.C.;
RT "Physical/genetic map of the 2p22-2p21 region on chromosome 2.";
RL Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP IDENTIFICATION (ISOFORM 1), INTERACTION WITH MICROTUBULES, AND SUBCELLULAR
RP LOCATION.
RX PubMed=18070910; DOI=10.1083/jcb.200705108;
RA Oishi K., Okano H., Sawa H.;
RT "RMD-1, a novel microtubule-associated protein, functions in chromosome
RT segregation in Caenorhabditis elegans.";
RL J. Cell Biol. 179:1149-1162(2007).
RN [9]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-139; TYR-152; THR-154 AND
RP THR-157, AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Liver;
RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L.,
RA Ye M., Zou H.;
RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver
RT phosphoproteome.";
RL J. Proteomics 96:253-262(2014).
CC -!- SUBUNIT: Interacts with microtubules. {ECO:0000269|PubMed:18070910}.
CC -!- INTERACTION:
CC Q96LZ7; Q6RW13: AGTRAP; NbExp=3; IntAct=EBI-2806908, EBI-741181;
CC Q96LZ7; Q6RW13-2: AGTRAP; NbExp=3; IntAct=EBI-2806908, EBI-11522760;
CC Q96LZ7; Q96DZ9: CMTM5; NbExp=3; IntAct=EBI-2806908, EBI-2548702;
CC Q96LZ7; Q96DZ9-2: CMTM5; NbExp=3; IntAct=EBI-2806908, EBI-11522780;
CC Q96LZ7; Q9NR28: DIABLO; NbExp=3; IntAct=EBI-2806908, EBI-517508;
CC Q96LZ7; Q8NBQ5: HSD17B11; NbExp=3; IntAct=EBI-2806908, EBI-1052304;
CC Q96LZ7; Q8IZV5: RDH10; NbExp=3; IntAct=EBI-2806908, EBI-11913715;
CC Q96LZ7; O95197-3: RTN3; NbExp=3; IntAct=EBI-2806908, EBI-11525735;
CC Q96LZ7; Q9NR31: SAR1A; NbExp=3; IntAct=EBI-2806908, EBI-3920694;
CC Q96LZ7; Q16623: STX1A; NbExp=3; IntAct=EBI-2806908, EBI-712466;
CC Q96LZ7; Q8WY91: THAP4; NbExp=3; IntAct=EBI-2806908, EBI-726691;
CC Q96LZ7; Q9UBN6: TNFRSF10D; NbExp=3; IntAct=EBI-2806908, EBI-1044859;
CC Q96LZ7; Q9P0L0: VAPA; NbExp=3; IntAct=EBI-2806908, EBI-1059156;
CC Q96LZ7; O95292: VAPB; NbExp=4; IntAct=EBI-2806908, EBI-1188298;
CC Q96LZ7; Q53XM7: VAPB; NbExp=3; IntAct=EBI-2806908, EBI-10178947;
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:18070910}.
CC Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18070910}.
CC Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:18070910}.
CC Note=In interphase localizes in the cytoplasm, and during mitosis
CC localizes to the spindle microtubules and spindle poles. Also detected
CC as large dots in the perinuclear region.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=4;
CC Name=1;
CC IsoId=Q96LZ7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q96LZ7-2; Sequence=VSP_025524, VSP_025527;
CC Name=3;
CC IsoId=Q96LZ7-3; Sequence=VSP_025525, VSP_025526;
CC Name=4;
CC IsoId=Q96LZ7-4; Sequence=VSP_025525;
CC -!- SIMILARITY: Belongs to the RMDN family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM81211.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AK057516; BAB71517.1; -; mRNA.
DR EMBL; AK095462; BAC04551.1; -; mRNA.
DR EMBL; AY358269; AAQ88636.1; -; mRNA.
DR EMBL; AF435956; AAM20907.1; -; mRNA.
DR EMBL; AC009229; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC016689; AAX88865.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00385.1; -; Genomic_DNA.
DR EMBL; CH471053; EAX00387.1; -; Genomic_DNA.
DR EMBL; BC024243; AAH24243.3; -; mRNA.
DR EMBL; AH011736; AAM81211.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BR000689; FAA00414.1; -; mRNA.
DR EMBL; BR000692; FAA00417.1; -; mRNA.
DR CCDS; CCDS1792.1; -. [Q96LZ7-2]
DR CCDS; CCDS54351.1; -. [Q96LZ7-1]
DR CCDS; CCDS54352.1; -. [Q96LZ7-4]
DR RefSeq; NP_001164262.1; NM_001170791.2. [Q96LZ7-1]
DR RefSeq; NP_001164263.1; NM_001170792.2. [Q96LZ7-1]
DR RefSeq; NP_001164264.1; NM_001170793.2. [Q96LZ7-4]
DR RefSeq; NP_001309140.1; NM_001322211.1. [Q96LZ7-1]
DR RefSeq; NP_653314.3; NM_144713.4.
DR RefSeq; XP_016858964.1; XM_017003475.1.
DR AlphaFoldDB; Q96LZ7; -.
DR SMR; Q96LZ7; -.
DR BioGRID; 127373; 34.
DR IntAct; Q96LZ7; 22.
DR STRING; 9606.ENSP00000234195; -.
DR iPTMnet; Q96LZ7; -.
DR PhosphoSitePlus; Q96LZ7; -.
DR BioMuta; RMDN2; -.
DR DMDM; 147643051; -.
DR EPD; Q96LZ7; -.
DR jPOST; Q96LZ7; -.
DR MassIVE; Q96LZ7; -.
DR MaxQB; Q96LZ7; -.
DR PaxDb; Q96LZ7; -.
DR PeptideAtlas; Q96LZ7; -.
DR PRIDE; Q96LZ7; -.
DR ProteomicsDB; 77272; -. [Q96LZ7-1]
DR ProteomicsDB; 77273; -. [Q96LZ7-2]
DR ProteomicsDB; 77274; -. [Q96LZ7-3]
DR ProteomicsDB; 77275; -. [Q96LZ7-4]
DR Antibodypedia; 29456; 165 antibodies from 22 providers.
DR DNASU; 151393; -.
DR Ensembl; ENST00000354545.8; ENSP00000346549.3; ENSG00000115841.21. [Q96LZ7-1]
DR Ensembl; ENST00000406384.5; ENSP00000386004.1; ENSG00000115841.21. [Q96LZ7-1]
DR Ensembl; ENST00000417700.6; ENSP00000392977.2; ENSG00000115841.21. [Q96LZ7-4]
DR GeneID; 151393; -.
DR KEGG; hsa:151393; -.
DR MANE-Select; ENST00000354545.8; ENSP00000346549.3; NM_001170791.3; NP_001164262.1.
DR UCSC; uc002rql.4; human. [Q96LZ7-1]
DR CTD; 151393; -.
DR DisGeNET; 151393; -.
DR GeneCards; RMDN2; -.
DR HGNC; HGNC:26567; RMDN2.
DR HPA; ENSG00000115841; Tissue enhanced (adrenal).
DR MIM; 611872; gene.
DR neXtProt; NX_Q96LZ7; -.
DR OpenTargets; ENSG00000115841; -.
DR PharmGKB; PA162387925; -.
DR VEuPathDB; HostDB:ENSG00000115841; -.
DR eggNOG; ENOG502QS2U; Eukaryota.
DR GeneTree; ENSGT00950000182992; -.
DR HOGENOM; CLU_046369_0_0_1; -.
DR InParanoid; Q96LZ7; -.
DR OMA; DLGQKNN; -.
DR OrthoDB; 1380644at2759; -.
DR PhylomeDB; Q96LZ7; -.
DR TreeFam; TF315854; -.
DR PathwayCommons; Q96LZ7; -.
DR SignaLink; Q96LZ7; -.
DR BioGRID-ORCS; 151393; 8 hits in 1073 CRISPR screens.
DR ChiTaRS; RMDN2; human.
DR GenomeRNAi; 151393; -.
DR Pharos; Q96LZ7; Tbio.
DR PRO; PR:Q96LZ7; -.
DR Proteomes; UP000005640; Chromosome 2.
DR RNAct; Q96LZ7; protein.
DR Bgee; ENSG00000115841; Expressed in adrenal tissue and 133 other tissues.
DR ExpressionAtlas; Q96LZ7; baseline and differential.
DR Genevisible; Q96LZ7; HS.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IDA:HPA.
DR GO; GO:0005794; C:Golgi apparatus; IDA:HPA.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0072686; C:mitotic spindle; IDA:HPA.
DR GO; GO:0097431; C:mitotic spindle pole; IDA:UniProtKB.
DR GO; GO:0005876; C:spindle microtubule; IDA:UniProtKB.
DR GO; GO:0008017; F:microtubule binding; IDA:UniProtKB.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR SUPFAM; SSF48452; SSF48452; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Cytoplasm; Cytoskeleton; Membrane;
KW Microtubule; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..410
FT /note="Regulator of microtubule dynamics protein 2"
FT /id="PRO_0000287504"
FT TRANSMEM 9..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 122..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 68..110
FT /evidence="ECO:0000255"
FT COMPBIAS 132..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 51
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8BSE0"
FT MOD_RES 121
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q498D5"
FT MOD_RES 139
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:24275569"
FT MOD_RES 152
FT /note="Phosphotyrosine"
FT /evidence="ECO:0007744|PubMed:24275569"
FT MOD_RES 154
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:24275569"
FT MOD_RES 157
FT /note="Phosphothreonine"
FT /evidence="ECO:0007744|PubMed:24275569"
FT VAR_SEQ 1..151
FT /note="MPYSTNKELILGIMVGTAGISLLLLWYHKVRKPGIAMKLPEFLSLGNTFNSI
FT TLQDEIHDDQGTTVIFQERQLQILEKLNELLTNMEELKEEIRFLKEAIPKLEEYIQDEL
FT GGKITVHKISPQHRARKRRLPTIQSSATSNSSEEAESEGG -> MGKCLSCCKEDQSFQ
FT RCSPEDQVSTDAQHRGASSISQPSISLGHKTSYSPVTHKVNAAKASRRLLSVSSPSFSE
FT RRYSLFVGFQKRNASPYWQQSRANFDSEEDTGFTDIKSSSDHCGSFISRRRRFSSRKLS
FT IVSYYKSAIFFDPQASGQNVFNLNEIEIFSKTSSNTDAKKHITISAPEYNTKNFKNFET
FT NTTSPAFGNTIDTASYQQSTSSFFSLASDISSPDQQNGIANDIQQRGQLCKDLKDFLHP
FT RPESYSTGHSPIMIPQHPSQSGTFPFLHKAGFSSSYKNSGCFIPPQSELTSGLFEDEDF
FT AVLFQDEDRSSPIEIPKIR (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_025524"
FT VAR_SEQ 1..151
FT /note="MPYSTNKELILGIMVGTAGISLLLLWYHKVRKPGIAMKLPEFLSLGNTFNSI
FT TLQDEIHDDQGTTVIFQERQLQILEKLNELLTNMEELKEEIRFLKEAIPKLEEYIQDEL
FT GGKITVHKISPQHRARKRRLPTIQSSATSNSSEEAESEGG -> MGKCLR (in
FT isoform 3 and isoform 4)"
FT /evidence="ECO:0000303|PubMed:14702039, ECO:0000303|Ref.3"
FT /id="VSP_025525"
FT VAR_SEQ 349..410
FT /note="AEELCPGYSNPNYMYLAKCYTDLEENQNALKFCNLALLLPTVTKEDKEAQKE
FT MQKIMTSLKR -> VHFVYPLF (in isoform 3)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_025526"
FT VAR_SEQ 394..410
FT /note="DKEAQKEMQKIMTSLKR -> EL (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_025527"
FT VARIANT 259
FT /note="G -> D (in dbSNP:rs4670800)"
FT /evidence="ECO:0000269|PubMed:14702039"
FT /id="VAR_032316"
FT CONFLICT Q96LZ7-2:259
FT /note="G -> D (in Ref. 1; BAB71517)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 410 AA; 47399 MW; DE5249E5808CA42A CRC64;
MPYSTNKELI LGIMVGTAGI SLLLLWYHKV RKPGIAMKLP EFLSLGNTFN SITLQDEIHD
DQGTTVIFQE RQLQILEKLN ELLTNMEELK EEIRFLKEAI PKLEEYIQDE LGGKITVHKI
SPQHRARKRR LPTIQSSATS NSSEEAESEG GYITANTDTE EQSFPVPKAF NTRVEELNLD
VLLQKVDHLR MSESGKSESF ELLRDHKEKF RDEIEFMWRF ARAYGDMYEL STNTQEKKHY
ANIGKTLSER AINRAPMNGH CHLWYAVLCG YVSEFEGLQN KINYGHLFKE HLDIAIKLLP
EEPFLYYLKG RYCYTVSKLS WIEKKMAATL FGKIPSSTVQ EALHNFLKAE ELCPGYSNPN
YMYLAKCYTD LEENQNALKF CNLALLLPTV TKEDKEAQKE MQKIMTSLKR
