RMD2_XENTR
ID RMD2_XENTR Reviewed; 412 AA.
AC Q0P4W3;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Regulator of microtubule dynamics protein 2;
DE Short=RMD-2;
DE AltName: Full=Protein FAM82A1;
GN Name=rmdn2; Synonyms=fam82a, fam82a1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RMDN family. {ECO:0000305}.
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DR EMBL; BC121878; AAI21879.1; -; mRNA.
DR RefSeq; NP_001072467.1; NM_001078999.1.
DR RefSeq; XP_017949431.1; XM_018093942.1.
DR AlphaFoldDB; Q0P4W3; -.
DR SMR; Q0P4W3; -.
DR STRING; 8364.ENSXETP00000063799; -.
DR PaxDb; Q0P4W3; -.
DR DNASU; 779922; -.
DR Ensembl; ENSXETT00000040010; ENSXETP00000040010; ENSXETG00000018480.
DR GeneID; 779922; -.
DR KEGG; xtr:779922; -.
DR CTD; 151393; -.
DR Xenbase; XB-GENE-951448; rmdn2.
DR eggNOG; ENOG502QS2U; Eukaryota.
DR InParanoid; Q0P4W3; -.
DR OrthoDB; 1380644at2759; -.
DR PhylomeDB; Q0P4W3; -.
DR Proteomes; UP000008143; Chromosome 5.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000018480; Expressed in liver and 11 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0097431; C:mitotic spindle pole; IBA:GO_Central.
DR GO; GO:0005876; C:spindle microtubule; IBA:GO_Central.
DR GO; GO:0008017; F:microtubule binding; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR SUPFAM; SSF48452; SSF48452; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..412
FT /note="Regulator of microtubule dynamics protein 2"
FT /id="PRO_0000287508"
FT TRANSMEM 9..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 106..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 157..184
FT /evidence="ECO:0000255"
SQ SEQUENCE 412 AA; 46623 MW; AC8244407512576E CRC64;
MSHSENKTLF LGVLAGAAGL SLTLLLLKRN RPRYLLGFSE IWSSAKETSA VQDNQGAVLI
LQGRQLQMLD KLGSLLKSVE ELKEEVKFLK DTLPKLEEQI RDELRGKNDA RKISPQHKGI
KRKKSETTKG AVEYPSSEEA ESEGGYITAH TDTELESDEE RGLKHLNAEN AKVTEEKAEL
LSVLYQADTG HCGSEPDKQD TFRMMLDNKE KYGNKVEFLW RLARAYGDMF DMTSDVEEKK
NYAANGKSIA GKAIQLEDCS AESHRWFAIM CGYLSEYESV QDKIKNGYLF KEHLDKAIEL
DPKDPLQYYL LGRWCYAVSQ LSWIERKVAA ALFGNPPTAT IQEALQNFLK VEEMHPGYSK
YNYVFLAKCY KDLGQKSVAL KYCDEASAMT AANKEDKDAQ KEMDTLMVSL KQ