ID   RMD6_YEAST              Reviewed;         231 AA.
AC   P39975; D3DLH9; Q6B1N5;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Sporulation protein RMD6;
DE   AltName: Full=Required for meiotic nuclear division protein 6;
GN   Name=RMD6; OrderedLocusNames=YEL072W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169868;
RA   Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA   Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA   Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA   Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA   Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA   Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA   Botstein D., Davis R.W.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL   Nature 387:78-81(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   FUNCTION.
RX   PubMed=12586695; DOI=10.1093/genetics/163.1.47;
RA   Enyenihi A.H., Saunders W.S.;
RT   "Large-scale functional genomic analysis of sporulation and meiosis in
RT   Saccharomyces cerevisiae.";
RL   Genetics 163:47-54(2003).
CC   -!- FUNCTION: Required for sporulation. Required for meiotic nuclear
CC       division. {ECO:0000269|PubMed:12586695}.
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DR   EMBL; U18795; AAB65015.1; -; Genomic_DNA.
DR   EMBL; AY693045; AAT93064.1; -; Genomic_DNA.
DR   EMBL; BK006939; DAA07583.1; -; Genomic_DNA.
DR   PIR; S50517; S50517.
DR   RefSeq; NP_010842.1; NM_001178887.1.
DR   AlphaFoldDB; P39975; -.
DR   BioGRID; 36659; 27.
DR   DIP; DIP-4097N; -.
DR   IntAct; P39975; 1.
DR   STRING; 4932.YEL072W; -.
DR   MaxQB; P39975; -.
DR   PaxDb; P39975; -.
DR   PRIDE; P39975; -.
DR   EnsemblFungi; YEL072W_mRNA; YEL072W; YEL072W.
DR   GeneID; 856637; -.
DR   KEGG; sce:YEL072W; -.
DR   SGD; S000000798; RMD6.
DR   VEuPathDB; FungiDB:YEL072W; -.
DR   eggNOG; ENOG502S44U; Eukaryota.
DR   HOGENOM; CLU_107283_0_0_1; -.
DR   InParanoid; P39975; -.
DR   OMA; CHERAFF; -.
DR   BioCyc; YEAST:G3O-30186-MON; -.
DR   PRO; PR:P39975; -.
DR   Proteomes; UP000002311; Chromosome V.
DR   RNAct; P39975; protein.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Meiosis; Reference proteome; Sporulation.
FT   CHAIN           1..231
FT                   /note="Sporulation protein RMD6"
FT                   /id="PRO_0000202600"
FT   CONFLICT        28
FT                   /note="Y -> D (in Ref. 3; AAT93064)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   231 AA;  26815 MW;  1C6A1A3CE19D5B1C CRC64;
     MSACPCNIVI LPVEILKNSS KDTKYSLYTT INRGYDVPRL KYGIIVSPRV HSLETLFSDL
     GFDKNIEKSS LYLLLNDPTL AYPNFHEHFE QLKGETNKDL SLPTYYIPKV QFLTEAFDSE
     HTLATIGYKP NNKESYEITG FTSMGNGYGI KLFNYSVIHM MRSHKCKRVV ADIIMEHDLL
     GYYEKKLGFV EVQRFKVLKE QHQVKVFDDK VDFTKDFHVI KMIKELGNHR L