ID   RMI1_ORYSJ              Reviewed;         817 AA.
AC   Q7XRV0; Q0JDM9;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2004, sequence version 2.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=RecQ-mediated genome instability protein 1;
DE   AltName: Full=BLM-associated protein of 75 kDa homolog;
DE            Short=BLAP75;
GN   Name=RMI1; OrderedLocusNames=Os04g0391000; ORFNames=OSJNBa0055C08.4;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
CC   -!- FUNCTION: Essential component of the RMI complex, a complex that plays
CC       an important role in the resolution step of homologous recombination,
CC       in a process called Holliday Junction dissolution, to limit DNA
CC       crossover formation in cells. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the RMI complex, containing at least TOP3A and
CC       RMI1. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RMI1 family. {ECO:0000305}.
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DR   EMBL; AL731600; CAE02280.2; -; Genomic_DNA.
DR   EMBL; AP008210; BAF14558.2; -; Genomic_DNA.
DR   EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_015633696.1; XM_015778210.1.
DR   RefSeq; XP_015633697.1; XM_015778211.1.
DR   RefSeq; XP_015633698.1; XM_015778212.1.
DR   AlphaFoldDB; Q7XRV0; -.
DR   SMR; Q7XRV0; -.
DR   STRING; 4530.OS04T0391000-00; -.
DR   PaxDb; Q7XRV0; -.
DR   PRIDE; Q7XRV0; -.
DR   GeneID; 4335680; -.
DR   KEGG; osa:4335680; -.
DR   eggNOG; ENOG502QPJ3; Eukaryota.
DR   HOGENOM; CLU_664610_0_0_1; -.
DR   InParanoid; Q7XRV0; -.
DR   OrthoDB; 531291at2759; -.
DR   Proteomes; UP000000763; Chromosome 4.
DR   Proteomes; UP000059680; Chromosome 4.
DR   Genevisible; Q7XRV0; OS.
DR   GO; GO:0016604; C:nuclear body; IBA:GO_Central.
DR   GO; GO:0031422; C:RecQ family helicase-topoisomerase III complex; IBA:GO_Central.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR   GO; GO:0000712; P:resolution of meiotic recombination intermediates; IBA:GO_Central.
DR   Gene3D; 2.40.50.770; -; 1.
DR   InterPro; IPR033472; DUF1767.
DR   InterPro; IPR039215; RMI1.
DR   InterPro; IPR032199; RMI1_C.
DR   InterPro; IPR013894; RMI1_N.
DR   InterPro; IPR042470; RMI1_N_C_sf.
DR   PANTHER; PTHR14790; PTHR14790; 1.
DR   Pfam; PF16099; RMI1_C; 1.
DR   Pfam; PF08585; RMI1_N; 1.
DR   SMART; SM01161; DUF1767; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..817
FT                   /note="RecQ-mediated genome instability protein 1"
FT                   /id="PRO_0000429783"
FT   REGION          1..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          595..639
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        57..76
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..117
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..198
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        595..613
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   817 AA;  88117 MW;  75CECE66AA68836C CRC64;
     MRRRNLIITS DSDSDDGGGG GGAATASTPA SASASASFPS VSGGGCGDGW PSPQNPRSVP
     VQFPSPSSPP PSPPIEISDE EEAEAEVVVE EEEVVVVEDE EEEYEEVEEI EDPDGDSPFV
     DAPEHISPPP PPPPPARTPM PTPTPTPTPT PTRPPVPVWA APLPARTPTP TPSAPPRAAA
     PSPAGTPSPS PIPPSSTPVS ALSGPLRQVD EFLRGLGLRL RPEWLESCAA GVPGFYGLGG
     VEAMARRCFE QFLFADMNAC GAGVLPEGVG SMHNAVLDGP LVLQVDEIVN LSAPLRERYR
     DAHAGPKRCL KLSMTDGIQR IYGMEYRPIK DLEVLAPAGF KIVIRNVHIR RGLFMLVPEV
     IEILGGVDDE LDEARNRLVS EVNKPPRGKR KQGGLPLSSR ATLAAWPTNA NATNDAEQGA
     SVPRTVNTPH PTRLGNASHA SQVGRTTQPM VDNLIPHVVV SNAQEQSRHI QEITMQGQPT
     SLNRHNKEAS ASYRYNAQCS ISGTTRAMAD EHVLVSNAQE QSPHIQEITM QDQSTSLNGR
     NKEASASTSY RYNAQCSISG TTRAMADERV DPSFVGNNVH EQMQRVQGIT MQDHISASSE
     SKRELSVTTP SGYDSRLAPH GVGNTGTRSG EATRSSNVDD GINNIGHPIS LCGENEKPFT
     YIFNMLADWG VQQDTVPYIQ GKIKGLITSV KRFQYKQSMQ YDLYVYIDDG SFITEAFVDR
     DIVQNMIGLS AEELAAALSS GGPAQANIRK TMKAFEHFLV NFEGTILIEL NRDSSVPIVR
     EMNKGCSSSD AWQLLRRVKT FSGQGYMRSL DFMDTTP