RMR1_ORYSJ
ID RMR1_ORYSJ Reviewed; 533 AA.
AC Q10R93; Q10R92; Q8S7T8;
DT 22-JAN-2014, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Receptor homology region, transmembrane domain- and RING domain-containing protein 1;
DE Short=OsRMR1;
DE Flags: Precursor;
GN OrderedLocusNames=Os03g0167500, LOC_Os03g07130; ORFNames=OSJNBa0091P11.36;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=21493745; DOI=10.1093/mp/ssr025;
RA Shen Y., Wang J., Ding Y., Lo S.W., Gouzerh G., Neuhaus J.M., Jiang L.;
RT "The rice RMR1 associates with a distinct prevacuolar compartment for the
RT protein storage vacuole pathway.";
RL Mol. Plant 4:854-868(2011).
CC -!- FUNCTION: Involved in the trafficking of vacuolar proteins. Functions
CC probably as a sorting receptor for protein trafficking to the protein
CC storage vacuole (PSV) by binding the C-terminal vacuolar sorting
CC determinant (VSD) of vacuolar-sorted proteins.
CC {ECO:0000269|PubMed:21493745}.
CC -!- SUBCELLULAR LOCATION: Prevacuolar compartment membrane
CC {ECO:0000269|PubMed:21493745}. Protein storage vacuole membrane
CC {ECO:0000269|PubMed:21493745}. Golgi apparatus membrane
CC {ECO:0000305|PubMed:21493745}; Single-pass type I membrane protein
CC {ECO:0000305|PubMed:21493745}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q10R93-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q10R93-2; Sequence=VSP_053580;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL84300.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC073556; AAL84300.1; ALT_SEQ; Genomic_DNA.
DR EMBL; DP000009; ABF94172.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF94173.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF10996.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS82487.1; -; Genomic_DNA.
DR EMBL; AK070468; BAG91973.1; -; mRNA.
DR RefSeq; XP_015632382.1; XM_015776896.1. [Q10R93-1]
DR RefSeq; XP_015632383.1; XM_015776897.1. [Q10R93-1]
DR RefSeq; XP_015632384.1; XM_015776898.1. [Q10R93-2]
DR AlphaFoldDB; Q10R93; -.
DR SMR; Q10R93; -.
DR STRING; 4530.OS03T0167500-01; -.
DR PaxDb; Q10R93; -.
DR PRIDE; Q10R93; -.
DR EnsemblPlants; Os03t0167500-01; Os03t0167500-01; Os03g0167500. [Q10R93-2]
DR EnsemblPlants; Os03t0167500-02; Os03t0167500-02; Os03g0167500. [Q10R93-1]
DR GeneID; 4331745; -.
DR Gramene; Os03t0167500-01; Os03t0167500-01; Os03g0167500. [Q10R93-2]
DR Gramene; Os03t0167500-02; Os03t0167500-02; Os03g0167500. [Q10R93-1]
DR KEGG; osa:4331745; -.
DR eggNOG; KOG4628; Eukaryota.
DR OMA; FMIVRCI; -.
DR OrthoDB; 1487241at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0032586; C:protein storage vacuole membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0044260; P:cellular macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd02123; PA_C_RZF_like; 1.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR044744; ZNRF4/RNF13/RNF167_PA.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Disulfide bond; Glycoprotein; Golgi apparatus;
KW Membrane; Metal-binding; Protein transport; Reference proteome; Signal;
KW Transmembrane; Transmembrane helix; Transport; Vacuole; Zinc; Zinc-finger.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..533
FT /note="Receptor homology region, transmembrane domain- and
FT RING domain-containing protein 1"
FT /id="PRO_0000425114"
FT TOPO_DOM 27..167
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 189..533
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 84..145
FT /note="PA"
FT ZN_FING 236..278
FT /note="RING-type; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT REGION 309..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 34
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 68..91
FT /evidence="ECO:0000255"
FT VAR_SEQ 395..428
FT /note="RYASPHMSHSGYASPSPHVSSSYVSNSGYGSSSY -> SY (in isoform
FT 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_053580"
SQ SEQUENCE 533 AA; 57168 MW; 7B04C66FA33DB434 CRC64;
MNRRRTMLLL ICLCATFCLM TQLGAANVVL MGTNLTLSFD DVEASFAPGV KGSGFEGVVY
TAEPLDACSP LTSKAEKGPP SPFALIIRGG CTFDEKVKNA QDAGFKAAIV YDNENSGVLI
SMAGSSGGIH IYAVFISKAS GEVLKKFSGH TDVEVWILPA FENSAWSIMA ISFISLLAMS
AVLATCFFVR RHHIRRDRPR IPEAREFHGM SSQLVKAMPS LIFTKVQEDN CTSSMCAICL
EDYNVGEKLR VLPCRHKFHA ACVDLWLTTW RTFCPVCKRD ASTGIPDPPA SETTPLLSSA
VRLPSQSSSF RSSVAASPPR PISRRPSSQS ISRIYAASGT PNSPNPIRSF TNSTAMSISR
SNVDLSNMSS RPRASHLASA HSLVGSHLSP PINIRYASPH MSHSGYASPS PHVSSSYVSN
SGYGSSSYYL GSSSQHRSYL RRCGESGPSL STMAPQSPQQ SQLRHGGESD LNLAGASSGQ
SFRQSYLRHC ADSEVNLAGA SSGQSFRQSY LRHCADSDAS LSAMASAQSL PGC
