ID   RN150_DANRE             Reviewed;         419 AA.
AC   Q566M8;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=RING finger protein 150;
DE   Flags: Precursor;
GN   Name=rnf150; ORFNames=zgc:92168;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
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DR   EMBL; BC093448; AAH93448.1; -; mRNA.
DR   RefSeq; NP_001017554.1; NM_001017554.2.
DR   AlphaFoldDB; Q566M8; -.
DR   SMR; Q566M8; -.
DR   STRING; 7955.ENSDARP00000013248; -.
DR   PaxDb; Q566M8; -.
DR   Ensembl; ENSDART00000024313; ENSDARP00000013248; ENSDARG00000009524.
DR   GeneID; 792211; -.
DR   KEGG; dre:792211; -.
DR   CTD; 792211; -.
DR   ZFIN; ZDB-GENE-050417-470; rnf150b.
DR   eggNOG; KOG0800; Eukaryota.
DR   GeneTree; ENSGT00940000156171; -.
DR   HOGENOM; CLU_049885_2_1_1; -.
DR   InParanoid; Q566M8; -.
DR   OMA; QDYHNPD; -.
DR   OrthoDB; 1487241at2759; -.
DR   PhylomeDB; Q566M8; -.
DR   TreeFam; TF317486; -.
DR   PRO; PR:Q566M8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 23.
DR   Bgee; ENSDARG00000009524; Expressed in mature ovarian follicle and 20 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Metal-binding; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix; Zinc; Zinc-finger.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000255"
FT   CHAIN           35..419
FT                   /note="RING finger protein 150"
FT                   /id="PRO_0000280699"
FT   TOPO_DOM        35..197
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        219..419
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          70..172
FT                   /note="PA"
FT   ZN_FING         267..308
FT                   /note="RING-type; atypical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          374..419
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..409
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   419 AA;  46350 MW;  A7CB322F34FEA72C CRC64;
     MALSVIQACR SLALSTWLLS FCFVHLLCLD FTVAEKEEWY TAFVNITYVD PDTAEVRTEK
     TECGRYGEHS LKREARGVLA MPAAPHDRHA CDPSGRFTPR AHGAWIALIS RGNCTYKDKI
     RHAVGHNASA VVIFNVGSSN PNETITMPHQ GISDVVAIMI PEPKGRELVL LMERNITVHM
     HITIGTRNLQ KYVSRTSVVF VSISFIILMI ISLAWLVFYY IQRFRYANAR DRNQRRLGDA
     AKKAISQLQV RTIRKGDQET ESDFDNCAVC IEGYKPNDVV RILPCRHLFH KCCVDPWLVD
     HRTCPMCKMN ILKALGLTSS AECLNELPLD YELAVGGVAL NAMVMSDDVM AGDVGGARDP
     GVRMGGLPQV LLDSEPLSQD TMPTEQSELQ PIASGSSDVS LTTGAGHSDI DTPTDDPKC