ID   RNA14_ASHGO             Reviewed;         661 AA.
AC   Q759Y6;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=mRNA 3'-end-processing protein RNA14;
GN   Name=RNA14; OrderedLocusNames=ADR137W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Component of the cleavage factor IA (CFIA) complex, which is
CC       involved in the endonucleolytic cleavage during polyadenylation-
CC       dependent pre-mRNA 3'-end formation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Nucleus and/or cytoplasm. {ECO:0000250}.
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DR   EMBL; AE016817; AAS52057.1; -; Genomic_DNA.
DR   RefSeq; NP_984233.1; NM_209586.1.
DR   AlphaFoldDB; Q759Y6; -.
DR   SMR; Q759Y6; -.
DR   STRING; 33169.AAS52057; -.
DR   PRIDE; Q759Y6; -.
DR   EnsemblFungi; AAS52057; AAS52057; AGOS_ADR137W.
DR   GeneID; 4620394; -.
DR   KEGG; ago:AGOS_ADR137W; -.
DR   eggNOG; KOG1914; Eukaryota.
DR   HOGENOM; CLU_007630_0_1_1; -.
DR   OMA; PKRQYFK; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005739; C:mitochondrion; IEA:EnsemblFungi.
DR   GO; GO:0005849; C:mRNA cleavage factor complex; IEA:EnsemblFungi.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0006378; P:mRNA polyadenylation; IEA:EnsemblFungi.
DR   GO; GO:0098789; P:pre-mRNA cleavage required for polyadenylation; IEA:EnsemblFungi.
DR   GO; GO:0072423; P:response to DNA damage checkpoint signaling; IEA:EnsemblFungi.
DR   GO; GO:0031123; P:RNA 3'-end processing; IBA:GO_Central.
DR   InterPro; IPR003107; HAT.
DR   InterPro; IPR045243; Rna14-like.
DR   InterPro; IPR008847; Suf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR19980; PTHR19980; 1.
DR   Pfam; PF05843; Suf; 1.
DR   SMART; SM00386; HAT; 8.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; mRNA processing; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..661
FT                   /note="mRNA 3'-end-processing protein RNA14"
FT                   /id="PRO_0000238517"
FT   REPEAT          67..99
FT                   /note="HAT 1"
FT   REPEAT          101..135
FT                   /note="HAT 2"
FT   REPEAT          149..181
FT                   /note="HAT 3"
FT   REPEAT          192..225
FT                   /note="HAT 4"
FT   REPEAT          262..298
FT                   /note="HAT 5"
FT   REPEAT          307..339
FT                   /note="HAT 6"
FT   REPEAT          513..548
FT                   /note="HAT 7"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   661 AA;  78068 MW;  A4FFCA2A07C84343 CRC64;
     MSGNETPDAG TVKSVSPSSG GSSLPARPTL RERDPNDIEN RLRDQIEEDP TQILLYIELI
     KYYVGKQQVA EIREVFGQLH ELFPLESFLW TIHLNWELEQ EESGQVETLL AKCLSGELMN
     NDIYLWSTYL GYVRRKNNTV TGGEEARGTV LKAYELVMEK CAVFEPRSMQ FWQDYLQFLE
     QWKPVSKWEE QSRVEILRKL YKRLLCLPVE SLERYWEKYT QWEQEVNQLT ARKFIGELSA
     SYMNARSLYQ EWSNLTKGLR RSLPTKLNQA TQQNLPAPGQ YDEYQLQIWT KWIQWELDNK
     LDLPEVVLRQ RVEYVHRQAV QHMCFAPEIW YNYAMFVDEN EHEKVLEIAV RCNPGSLSLT
     FKLAEYLELN NKIEALEERF QHCIARISME LQVMNDTTMD PDKILRQTRK LTFAYCVYMT
     TMKRVTGLSA ARKVFSKCRK LKKDISYEIY VENAYMEYYN NSDVTTPCRV LEFGLKYFQD
     NGNYINKYLD FLILVKQDAQ IKSLFESCID KIYNLDQLKE IYKKVINYES KFGNLNNVYE
     LERRFFEKFP EAEKIEVFTD RYQLQGENLL KRLEFPYLMD EYGIPVLSGY AVKRSLHSAG
     IVFDDNGSSK RQRQEQTEAV PMEIIELLKV LPKRQYFKTI VLDPHKLADF LSDKVTIPPC
     D